A 76-year-old woman presented to our department for the evaluation of multiple polyps in the stomach, incidentally detected during screening endoscopy. Endoscopy revealed multiple, reddish, nodular lesions with variable sizes in the background of atrophic gastritis in the gastric body and fundus (Fig. 1A). Magnifying endoscopy with narrow-band imaging (MENBI) of the reddish nodular lesions revealed small, round pits surrounded by honeycomb-type subepithelial capillary networks (SECNs) with a regular arrangement of collecting venules (Fig. 1B, Supplementary Video 1). However, ME-NBI of the surrounding atrophic mucosa revealed loss of the normal SECNs and round pits, with an irregular arrangement of the collecting venules (Fig. 1C). Rapid urease test and histological examination for Helicobacter pylori were negative. Endoscopic biopsy of the reddish nodular lesions revealed well-preserved oxyntic glands without evidence of atrophy or intestinal metaplasia, and pseudohypertrophy of parietal cells with protrusion into the gland lumen (Fig. 1D). On the contrary, endoscopic biopsy for surrounding flat mucosa revealed severe atrophic changes with hardly preserved oxyntic glands.