Korean Journal of Gastrointestinal Endoscopy 2006;32(3): 194-199.
상부 위장관 출혈로 발현된 위를 침범한 CD56+ NK/T 세포 림프종 1예
오희정·심기남·송지현·송현주·유금혜·이창배·김태헌·정성애·유권·문일환·이시내*
이화여자대학교 의과대학 내과학교실, *병리학교실, 의과학 연구소
A Case of Gastric CD56+ Extranodal NK/T-cell Lymphoma, Nasal Type
Hee Jung Oh, M.D., Ki-Nam Shim, M.D., Ji Hyun Song, M.D., Hyun Joo Song, M.D., Kum Hei Ryu, M.D., Chang Bai Lee, M.D., Tae Hun Kim, M.D., Sung-Ae Jung, M.D., Kwon Yoo, M.D., Il-Hwan Moon, M.D. and Shi Nae Lee, M.D.*
Departments of Internal Medicine and *Pathology, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea
Abstract
A NK/T cell lymphoma is highly aggressive lymphoma of a putative NK-cell origin with a predominant extranodal presentation and a rapidly fatal course. CD56 has been reported to be the most reliable marker for a NK/T cell lymphoma. A NK/T cell lymphoma is strongly associated with the Epstein-Barr virus. We report a case of an aggressive NK/T cell lymphoma presenting as a gastric ulcer. A 52-year-old female patient presented with hematochezia and fever. The endoscopic finding showed a gastric ulcer with a recent bleeding stigma. Histologically, the gastric biopsy showed a diffuse infiltration of small or medium sized lymphoma cells with an angiocentric growth pattern and necrosis. The lymphoma cells were CD56, CD3, CD20, which are consistent with a NK/T cell lymphoma. Unfortunately, the patient was discharged without treatment. We report this case with a review of the relevant literature. (Korean J Gastrointest Endosc 2006;32:194199)
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