Korean Journal of Gastrointestinal Endoscopy 2008;36(5): 307-312.
고용량 스테로이드와 Azathioprine 병합요법으로 치료된 장 아밀로이드증 1예
김성규ㆍ권중구ㆍ조창호*ㆍ오지혜ㆍ김수경
대구가톨릭대학교 의과대학 내과학교실, *병리학교실
Intestinal Amyloidosis Treated with High-Dose Steroids and Azathioprine: A Case Report
Seong-Kyu Kim, M.D., Joong Goo Kwon, M.D., Chang Ho Cho, M.D.*, Ji-Hye Oh, M.D. and Soo-Kyung Kim, M.D.
Departments of Internal Medicine and *Pathology, Catholic University of Daegu School of Medicine, Daegu, Korea
Abstract
Amyloidosis is a rare disease characterized by deposition and accumulation of insoluble fibrils in various organs and tissues. Variations in the precursor proteins composing each fibril account for the diverse character of amyloidosis. Amyloidosis light chain (AL) and amyloid A amyloidosis (AA) are two clinical entities representative of this diversity. We present a case of a 58-year-old woman presenting with refractory diarrhea and abdominal pain. She was ultimately diagnosed with intestinal amyloidosis diffusely involving the small and large intestines. Even though a definitive therapeutic strategy has not been established for gastrointestinal amyloidosis, this particular patient has been successfully managed with high-dose steroids and azathioprine. (Korean J Gastrointest Endosc 2008; 36:307-312)
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