Korean Journal of Gastrointestinal Endoscopy 2008;37(1): 65-70.
스테로이드 유지요법에도 급격히 악화된 자가면역 만성 췌장염 1예
황재철ㆍ유병무ㆍ고경현ㆍ김동훈ㆍ강창준ㆍ정재학*ㆍ박병준*ㆍ김진홍
아주대학교 의과대학 내과학교실, *목포한국병원 내과
A Case of Autoimmune Chronic Pancreatitis that was Rapidly AggravatedDespite Oral Steroid Maintenance Therapy
Jae Chul Hwang, M.D., Byung Moo Yoo, M.D., Kyung Hyun Koh, M.D., Dong Hoon Kim, M.D., Chang Joon Kang, M.D., Jai Hak Jeung, M.D.*, Byoung Joon Park, M.D.* and Jin Hong Kim, M.D.
Department of Internal Medicine, Ajou University School of Medicine, Suwon, *Department of Internal Medicine, Mokpo Hankook Hospital, Mokpo, Korea
Abstract
In a case of autoimmune chronic pancreatitis that relapsed despite maintenance therapy with low-dose steroid, high- dose steroid can induce remission of the disease, and maintenance therapy of steroid is usually recommended in that case. A 57-year-old man developed epigastric pain and jaundice. The patient was diagnosed with autoimmune chronic pancreatitis. The abnormalities in the clinical, laboratory and radiologic findings improved after oral steroid therapy. After two relapsed episodes, maintenance therapy of steroid with 5 mg prednisolone/day was administrated. In the studies for follow up, the level of serum IgG was increased and abdominal computed tomography showed calcification and pseudocyst in the pancreatic tail. To our knowledge, this is a rare case of autoimmune chronic pancreatitis aggravated rapidly despite oral steroid maintenance therapy. (Korean J Gastrointest Endosc 2008;37:65-70)
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