Korean Journal of Gastrointestinal Endoscopy 2010;41(6): 385-389.
궤양성 대장염 진단과 동시에 발견된 거대세포바이러스 대장염 1예
이효근ㆍ배원기ㆍ류우선ㆍ송태준ㆍ김남훈ㆍ김경아ㆍ이준성ㆍ주 미*
인제대학교 의과대학 일산백병원 내과학교실, *병리학교실
Cytomegalovirus Colitis with Ulcerative Colitis in the Steroid Naïve Immunocompetent Patient
Hyo Keun Lee, M.D., Won Ki Bae, M.D., Woo Sun Rou, M.D., Tae Jun Song, M.D., Nam-Hoon Kim, M.D., Kyung-Ah Kim, M.D., June Sung Lee, M.D. and Mee Joo, M.D.*
Departments of Internal Medicine and *Pathology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea
Abstract
Ulcerative colitis is an idiopathic chronic inflammatory bowel disease that exclusively involves the colon. It is characterized by diffuse mucosal inflammation and a recurrent course of remission and relapse. Factors such as smoking, diet, genetic factors and miocrobial infection have all been suggested as causes of ulcerative colitis. One of the important issues in the treatment of ulcerative colitis is opportunistic infection associated with the usage of corticosteroid and immunosuppresant. In most cases, opportunistic cytomegalovirus infection after treatment with corticosteroid or immunosuppressant worsens the course of ulcerative colitis. However, cytomegalovirus infection is uncommon in immunocompetent patients and it is rare in immunocompetent patients with corticosteroid naive ulcerative colitis. We report here on a case in which an immunocompetent patient was newly diagnosed with ulcerative colitis and cytomegalovirus coinfection simultaneously. (Korean J Gastrointest Endosc 2010;41:385-389)