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Ahmed Youssef Altonbary 2 Articles
Role of Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Portal Vein Thrombus in the Diagnosis and Staging of Hepatocellular Carcinoma
Dina Eskandere, Hazem Hakim, Magdy Attwa, Wagdi Elkashef, Ahmed Youssef Altonbary
Clin Endosc 2021;54(5):745-753.   Published online March 15, 2021
DOI: https://doi.org/10.5946/ce.2020.240
AbstractAbstract PDFPubReaderePub
Background
/Aims: Malignant portal vein thrombus (PVT) is found in up to 44% of patients with hepatocellular carcinoma (HCC). The nature of the thrombus influences treatment selection. The aim of this study was to assess the safety and efficacy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in determining the nature of PVT in liver cirrhosis and/or HCC.
Methods
A prospective study was conducted in 34 patients with liver cirrhosis and/or HCC with PVT. Under EUS guidance, PVT was punctured using a 22 G FNA needle (Cook Medical, Bloomington, IN, USA) followed by monitoring of the puncture tract using color Doppler. Patients were followed for adverse events 2 hours after recovery.
Results
Throughout the 30-month study period, 34 patients, including 24 males with a mean age of 59±8 years, were enrolled. There were 8 patients with known HCC and 26 with no liver masses detected by computed tomography (CT). EUS-FNA from PVT was positive for malignancy in 3 patients (8.8%), of which only 1 patient was diagnosed with HCC by CT and 2 patients were newly diagnosed with HCC after EUS-FNA. No major complications were reported.
Conclusions
EUS-FNA is a safe and effective technique for determining the nature of PVT that does not fulfill the malignant criteria via imaging studies in patients with liver cirrhosis and/or HCC.

Citations

Citations to this article as recorded by  
  • Endoscopic ultrasound-guided vascular interventions: An overview of current and emerging techniques
    Ahmed Youssef Altonbary
    International Journal of Gastrointestinal Intervention.2023; 12(1): 16.     CrossRef
  • 3,834 View
  • 103 Download
  • 1 Web of Science
  • 1 Crossref
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Diagnostic Efficacy of Endoscopic Ultrasound Elastography in Differentiating Solid Pancreatic Lesions: A Single-Center Experience
Ahmed Youssef Altonbary, Hazem Hakim, Ahmed Mohamed El-Shamy
Clin Endosc 2019;52(4):360-364.   Published online January 8, 2019
DOI: https://doi.org/10.5946/ce.2018.160
AbstractAbstract PDFPubReaderePub
Background
/Aims: Endoscopic ultrasound (EUS) has a limited ability to determine the nature of solid pancreatic lesions (SPLs). Most recent ultrasound processors are provided with elastography software, which allows quantification of the tissue hardness. The aim of this study is to evaluate the effectiveness of the elasticity score (ES) and strain ratio (SR) in the differentiation of benign pancreatic lesions from malignant pancreatic lesions.
Methods
The study had a retrospective design; it included 97 patients with SPLs and 19 patients with inflammatory lesions. The ES and SR were determined during the examination; finally, EUS-guided fine needle aspiration was performed.
Results
In this 2-year study, 116 patients were enrolled (97 with malignant lesions and 19 with benign lesions). There were 69 men and 47 women. Their median age was 55.9 years. A cut-off point was detected at SR of 7.75 with a specificity of 99.9%, sensitivity of 90.7%, positive predictive value (PPV) of 99.9%, negative predictive value (NPV) of 67.9%, and accuracy of 92.2%. After adding the ES to the SR, the cut-off point at 7.75 resulted in a specificity of 94.6%, sensitivity of 99%, PPV of 98%, NPV of 98.5%, and accuracy of 97%.
Conclusions
The use of the ES combined with the SR increases the accuracy of differentiation between benign and malignant SPLs and is an effective method for the evaluation of pancreatic masses.

Citations

Citations to this article as recorded by  
  • Diagnostic performance of endoscopic ultrasound elastography for differential diagnosis of solid pancreatic lesions: A propensity score-matched analysis
    In Rae Cho, Seok-Hoo Jeong, Huapyong Kang, Eui Joo Kim, Yeon Suk Kim, Soyoung Jeon, Jae Hee Cho
    Pancreatology.2023; 23(1): 105.     CrossRef
  • The expanding role of endoscopic ultrasound elastography
    Jahnvi Dhar, Jayanta Samanta
    Clinical Journal of Gastroenterology.2022; 15(5): 841.     CrossRef
  • Endoscopic ultrasound elastography for malignant pancreatic masses and associated lymph nodes: Critical evaluation of strain ratio cutoff value
    Miguel Puga-Tejada, Raquel Del Valle, Roberto Oleas, Maria Egas-Izquierdo, Martha Arevalo-Mora, Jorge Baquerizo-Burgos, Jesenia Ospina, Miguel Soria-Alcivar, Hannah Pitanga-Lukashok, Carlos Robles-Medranda
    World Journal of Gastrointestinal Endoscopy.2022; 14(9): 524.     CrossRef
  • Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Pancreatic Cancer
    Yasutaka Ishii, Masahiro Serikawa, Tomofumi Tsuboi, Ryota Kawamura, Ken Tsushima, Shinya Nakamura, Tetsuro Hirano, Ayami Fukiage, Takeshi Mori, Juri Ikemoto, Yusuke Kiyoshita, Sho Saeki, Yosuke Tamura, Sayaka Miyamoto, Kazuaki Chayama
    Diagnostics.2021; 11(2): 238.     CrossRef
  • Impact of endoscopic ultrasound elastography in pancreatic lesion evaluation
    Cosmas Rinaldi Adithya Lesmana, Maria Satya Paramitha
    Artificial Intelligence in Gastrointestinal Endoscopy.2021; 2(4): 168.     CrossRef
  • Utilidad de la elastografía cuantitativa por ultrasonografía endoscópica (USE), para el diagnóstico de las lesiones sólidas del páncreas (LSP).
    Martín Alonso Gómez Zuleta, Oscar Fernando Ruíz Morales, Diego Fernando Cano Rosales
    Revista colombiana de Gastroenterología.2021; 36(4): 434.     CrossRef
  • 5,006 View
  • 146 Download
  • 4 Web of Science
  • 6 Crossref
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