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Alan Barkun 1 Article
Risk Stratification in Cancer Patients with Acute Upper Gastrointestinal Bleeding: Comparison of Glasgow-Blatchford, Rockall and AIMS65, and Development of a New Scoring System
Matheus Cavalcante Franco, Sunguk Jang, Bruno da Costa Martins, Tyler Stevens, Vipul Jairath, Rocio Lopez, John J. Vargo, Alan Barkun, Fauze Maluf-Filho
Clin Endosc 2022;55(2):240-247.   Published online January 21, 2022
DOI: https://doi.org/10.5946/ce.2021.115
AbstractAbstract PDFPubReaderePub
Background
/Aims: Few studies have measured the accuracy of prognostic scores for upper gastrointestinal bleeding (UGIB) among cancer patients. Thereby, we compared the prognostic scores for predicting major outcomes in cancer patients with UGIB. Secondarily, we developed a new model to detect patients who might require hemostatic care.
Methods
A prospective research was performed in a tertiary hospital by enrolling cancer patients admitted with UGIB. Clinical and endoscopic findings were obtained through a prospective database. Multiple logistic regression analysis was performed to gauge the power of each score.
Results
From April 2015 to May 2016, 243 patients met the inclusion criteria. The AIMS65 (area under the curve [AUC] 0.85) best predicted intensive care unit admission, while the Glasgow-Blatchford score best predicted blood transfusion (AUC 0.82) and the low-risk group (AUC 0.92). All scores failed to predict hemostatic therapy and rebleeding. The new score was superior (AUC 0.74) in predicting hemostatic therapy. The AIMS65 (AUC 0.84) best predicted in-hospital mortality.
Conclusions
The scoring systems for prognostication were validated in the group of cancer patients with UGIB. A new score was developed to predict hemostatic therapy. Following this result, future prospective research should be performed to validate the new score.

Citations

Citations to this article as recorded by  
  • Endoscopic Management of Tumor Bleeding
    Frances Dang, Marc Monachese
    Gastrointestinal Endoscopy Clinics of North America.2024; 34(1): 155.     CrossRef
  • The Accuracy of Pre-Endoscopic Scores for Mortality Prediction in Patients with Upper GI Bleeding and No Endoscopy Performed
    Sergiu Marian Cazacu, Dragoș Ovidiu Alexandru, Răzvan-Cristian Statie, Sevastița Iordache, Bogdan Silviu Ungureanu, Vlad Florin Iovănescu, Petrică Popa, Victor Mihai Sacerdoțianu, Carmen Daniela Neagoe, Mirela Marinela Florescu
    Diagnostics.2023; 13(6): 1188.     CrossRef
  • Progress in the Evaluation of Acute Upper Gastrointestinal Bleeding with AIMS65 Scoring System
    莉 王
    Advances in Clinical Medicine.2023; 13(05): 8163.     CrossRef
  • Interpretations of the Role of Plasma Albumin in Prognostic Indices: A Literature Review
    Kim Oren Gradel
    Journal of Clinical Medicine.2023; 12(19): 6132.     CrossRef
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