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Edris Wedi 2 Articles
Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature
Edris Wedi, Beatrice Orlandini, Mark Gromski, Carlo Felix Maria Jung, Irina Tchoumak, Stephanie Boucher, Volker Ellenrieder, Jürgen Hochberger
Clin Endosc 2018;51(1):103-108.   Published online January 31, 2018
AbstractAbstract PDFPubReaderePub
The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data.
Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectal lesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-lifting colonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in a young patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinical success rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm.
Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrin tumors, incomplete endoscopic resection (R1) or T1 carcinoma.
Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for either surgical or conventional endoscopic resection strategies.


Citations to this article as recorded by  
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    Cirugía Española.2023; 101(6): 435.     CrossRef
  • Multicenter clinical trial for the resection of rectal polyps using a new laparoendoscopic hybrid transanal access device
    José Francisco Noguera Aguilar, Alba Gómez Dovigo, Javier Aguirrezabalaga González, Benito González Conde, Pedro Alonso Aguirre, David Martínez Ares, Javier Sánchez González, María Pilar Díez Redondo, Olga Maseda Díaz, Maria Ignacia Torres García, Andrés
    Cirugía Española (English Edition).2023; 101(6): 435.     CrossRef
  • A novel strategy to perform endoscopic full-thickness resection at the ileocecal valve and securing the orifice with a double-pigtail catheter
    Moritz Meiborg, Nicolae-Catalin Mechie, Tobias Blasberg, Marie Weber, Edris Wedi
    Endoscopy.2023; 55(S 01): E375.     CrossRef
  • Novel Sequence of Endoscopic Therapy for the Management of Colonic Adenocarcinoma and Surrounding Adenoma
    Adam W. Scott, Khalid Amin, Justin R. Howard, Stuart K. Amateau
    ACG Case Reports Journal.2023; 10(2): e01008.     CrossRef
  • Distal Cap-assisted Endoscopic Mucosal Resection for Non-lifting Colorectal Polyps: An International, Multicenter Study
    Scott R. Douglas, Douglas K. Rex, Alessandro Repici, Melissa Kelly, J. Wes Heinle, Marco Spadaccini, Matthew T. Moyer
    Techniques and Innovations in Gastrointestinal Endoscopy.2023; 25(3): 236.     CrossRef
  • A novel strategy to perform endoscopic full-thickness resection at the ileocecal valve and securing the orifice with a double-pigtail catheter
    Moritz Meiborg, Nicolae-Catalin Mechie, Tobias Blasberg, Marie Weber, Edris Wedi
    Endoscopy.2023; 55(06): 583.     CrossRef
  • Endoscopic mucosal resection and endoscopic submucosal dissection with an external additional working channel (EMR+ and ESD+) are equivalent to using a double-channel endoscope: a systematic evaluation in a porcine ex vivo model
    Richard F. Knoop, Ahmad Amanzada, Golo Petzold, Volker Ellenrieder, Michael Engelhardt, Albrecht Neesse, Sebastian C. B. Bremer, Steffen Kunsch
    Surgical Endoscopy.2023; 37(10): 7749.     CrossRef
  • EMR + with the AWC improves endoscopic resection speed compared to ESD: a porcine ex-vivo pilot study
    Edris Wedi, Richard Knoop, Carlo Jung, Mark Gromski, Chi Nghia Ho, Gabor Conrad, Juergen Maiss, Sinisa Milenovic, David Klemme, Ulrich Baulain, Ali Seif Amir Hosseini, Volker Ellenrieder, Peter Koehler
    Minimally Invasive Therapy & Allied Technologies.2021; 30(1): 47.     CrossRef
  • Endoscopic submucosal dissection with an additional working channel (ESD+): a novel technique to improve procedure time and safety of ESD
    Richard F. Knoop, Edris Wedi, Golo Petzold, Sebastian C. B. Bremer, Ahmad Amanzada, Volker Ellenrieder, Albrecht Neesse, Steffen Kunsch
    Surgical Endoscopy.2021; 35(7): 3506.     CrossRef
  • Novel modified endoscopic mucosal resection of large GI lesions (> 20 mm) using an external additional working channel (AWC) may improve R0 resection rate: initial clinical experience
    A. Sportes, Jung CFM, M. A. Gromski, P. Koehler, A. Seif Amir Hosseini, P. Kauffmann, V. Ellenrieder, E. Wedi
    BMC Gastroenterology.2020;[Epub]     CrossRef
  • Devices and techniques for endoscopic treatment of residual and fibrotic colorectal polyps (with videos)
    Arvind J. Trindade, Nikhil A. Kumta, Manoop S. Bhutani, Vinay Chandrasekhara, Pichamol Jirapinyo, Kumar Krishnan, Joshua Melson, Rahul Pannala, Mansour A. Parsi, Allison R. Schulman, Guru Trikudanathan, Rabindra R. Watson, John T. Maple, David R. Lichtens
    Gastrointestinal Endoscopy.2020; 92(3): 474.     CrossRef
  • Endoskopisches Management von kolorektalen Adenomen, HGIEN und Frühkarzinomen
    Michael Hünerbein, Frank Kolligs
    Onkologie up2date.2020; 2(04): 311.     CrossRef
  • Comparison of Endoscopic Submucosal Dissection for Primary and Recurrent Colorectal Lesions: A Single-Center European Study
    Michał Spychalski, Aleksander Skulimowski, Makoto Nishimura, Adam Dziki
    Journal of Laparoendoscopic & Advanced Surgical Techniques.2019; 29(3): 366.     CrossRef
  • Optimal Management of Malignant Polyps, From Endoscopic Assessment and Resection to Decisions About Surgery
    Douglas K. Rex, Aasma Shaukat, Michael B. Wallace
    Clinical Gastroenterology and Hepatology.2019; 17(8): 1428.     CrossRef
  • Endoscopic full-thickness resection of early mucosal neoplasms
    Andreas Wannhoff, Karel Caca
    Techniques in Gastrointestinal Endoscopy.2019; 21(1): 13.     CrossRef
  • Endoscopic full-thickness resection for early colorectal cancer
    Armin Kuellmer, Julius Mueller, Karel Caca, Patrick Aepli, David Albers, Brigitte Schumacher, Anne Glitsch, Claus Schäfer, Ingo Wallstabe, Christopher Hofmann, Andreas Erhardt, Benjamin Meier, Dominik Bettinger, Robert Thimme, Arthur Schmidt
    Gastrointestinal Endoscopy.2019; 89(6): 1180.     CrossRef
  • Future of full thickness resection – Devices, indications, robotics, what is missing
    Philip WY Chiu
    Techniques in Gastrointestinal Endoscopy.2019; 21(1): 48.     CrossRef
  • Clips for managing perforation and bleeding after colorectal endoscopic mucosal resection
    A. S. Turan, G. Ultee, E. J. M. Van Geenen, P. D. Siersema
    Expert Review of Medical Devices.2019; 16(6): 493.     CrossRef
  • Technical Feasibility of a Guidetube for Various Endoscopic Procedures in Human Gastrointestinal Simulators
    Dong Seok Lee, Byeong Gwan Kim, Kook Lae Lee, Yong Jin Jung, Ji Won Kim
    Clinical Endoscopy.2019; 52(3): 247.     CrossRef
  • Now, More than Ever Before, Colonoscopy Is a Therapeutic Procedure
    Ana Catarina Ribeiro Gomes, Rolando Pinho
    GE - Portuguese Journal of Gastroenterology.2019; 26(4): 229.     CrossRef
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Combined Endoscopic and Surgical Treatment of Severe Gastrointestinal Bleeding in a Patient with Heart Assist Device under Therapeutic Anticoagulation
Edris Wedi, Mohamed Bounnah, Riccardo Memeo, Carlo Jung
Clin Endosc 2017;50(6):598-601.   Published online June 1, 2017
AbstractAbstract PDFPubReaderePub
Gastrointestinal (GI) bleeding is a common complication after heart assist device placement. Reasons for bleeding are multifactorial. Endoscopic therapy is the treatment of choice, whereas invasive procedures are avoided in these critically ill patients. We present the case of a 65-year-old male patient experiencing severe GI bleeding after left ventricular assist device (LVAD) and right ventricular assist device (RVAD) placement with therapeutic anticoagulation. Endoscopically, multiple gastric bleeding sources were found but could not be treated effectively due to a large blood clot. A combined endoscopic and surgical treatment was initiated, including gastrotomy for blood clot removal, surgical transgastric suturing, endoscopic over-the-scope clip (OTSC) placement and hemospray application. Postoperative endoscopic visualization showed effective bleeding control. The patient unfortunately died due to causes unrelated to the treatment. This case shows that a minimal invasive combination of endoscopic and surgical techniques can be an alternative treatment for severe upper GI bleeding in critically ill and anticoagulated patients.
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