The incidence of early gastric cancer (EGC) has increased to >50% in Korea owing to a higher detection rate caused by rapid advances in diagnostic instrumentation. EGC with distant metastasis has been rarely reported. Here, we report the case of a 76-year-old woman in whom general EGC was initially diagnosed by endoscopy and endoscopic ultrasonography. She subsequently underwent endoscopic submucosal dissection (ESD). Histological examination of the ESD specimen revealed that neoplastic cells were located predominantly in the submucosal layer and submucosal lymphatic channels. Metastatic cancer cells were also found in the pleural effusion. After conducting all analyses, including immunohistochemical staining, we concluded that the patient had primary EGC with pleural metastasis.

Citations

Citations to this article as recorded by  

• Clinicopathological Characteristics and Prognosis of cT1N0M1 Gastric Cancer: A Population-Based Study
  Jianbo Han, Junhao Tu, Chaoyang Tang, Xiang Ma, Chi Huang
  Disease Markers.2019; 2019: 1.     CrossRef
• The Value of Computed Tomography in Preoperative N Staging of Early Gastric Cancer Meeting the Endoscopic Resection Criteria
  Su Jin Kim, Tae Un Kim, Cheol Woong Choi, Dae Hwan Kang, Hyung Wook Kim, Su Bum Park, Hyeong Seok Nam, Dae Gon Ryu
  The Korean Journal of Gastroenterology.2017; 70(1): 21.     CrossRef
• An Early Gastric Cancer Patient With Pleural Metastatic Recurrence
  Asako Shimazaki, Takao Katsube, Kentaro Yamaguchi, Atsuko Usuda, Minoru Murayama, Soihi Konno, Shinichi Asaka, Hajime Yokomizo, Kazuhiko Yoshimatsu, Shunichi Shiozawa, Takeshi Shimakawa, Yoshihiko Naritaka
  International Surgery.2016; 101(1-2): 84.     CrossRef
• Collagen Nanofibers Facilitated Presynaptic Maturation in Differentiated Neurons from Spinal-Cord-Derived Neural Stem Cells through MAPK/ERK1/2-Synapsin I Signaling Pathway
  Yanling Yin, Peng Huang, Zhu Han, Guojun Wei, Changwei Zhou, Jian Wen, Bo Su, Xiaoqin Wang, Yansong Wang
  Biomacromolecules.2014; 15(7): 2449.     CrossRef

Solitary pancreatic metastasis of esophageal cancer is extremely rare. We report the case of a 58-year-old male admitted with esophageal cancer. Additional asymptomatic solitary hepatic and pancreatic masses were observed in the staging work-up for esophageal cancer. The hepatic mass was confirmed as a primary hepatocellular carcinoma with an ultrasound-guided needle biopsy. An esophagectomy with a distal pancreatectomy and radiofrequency ablation for hepatocellular carcinoma were performed. Histologically, the pancreatic mass was confirmed to be a metastasis from the esophageal cancer. The patient has been followed up with chemotherapy.

Citations

Citations to this article as recorded by  

• Pancreatic Metastases of Esophageal Squamous Cell Carcinoma: A Case Report and Review of the Literature
  Tivadar Bara, Alexandra Georgiana Scurtu, Tivadar Bara, Zsolt Zoltan Fulop, Renata Moriczi, Patricia Simu, Paul Borz, Simona Gurzu
  Diagnostics.2024; 14(19): 2164.     CrossRef
• A case of esophageal squamous cell carcinoma accompanied by pancreatic and bile duct metastases: Successful treatment starts with an accurate diagnosis
  Yuki Ito, Yoshihiro Ikura, Hiroaki Sawai, Tatsuya Osuga
  Journal of Cancer Research and Therapeutics.2023; 19(7): 2060.     CrossRef
• Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review
  Yuki Denda, Yoichi Matsuo, Keisuke Nonoyama, Hiromichi Murase, Tomokatsu Kato, Yuichi Hayashi, Hiroyuki Imafuji, Kenta Saito, Mamoru Morimoto, Hiroyuki Kato, Michihiro Yoshida, Itaru Naitoh, Kazuki Hayashi, Ryo Ogawa, Hiroki Takahashi, Shuji Takiguchi
  Molecular and Clinical Oncology.2023;[Epub]     CrossRef
• Malignant biliary obstruction due to metastatic non-hepato-pancreato-biliary cancer
  Takeshi Okamoto
  World Journal of Gastroenterology.2022; 28(10): 985.     CrossRef
• An extremely atypical presentation of esophageal squamous cell carcinoma with pancreatic and hepatic metastases
  Lei Zhang, Xin Long, Zheng-Nan Hu, Yu Wu, Jia Song, Bi-Xiang Zhang, Wei-Xun Chen
  Medicine.2021; 100(20): e25785.     CrossRef
• Primary squamous cell carcinoma of head of the pancreas
  Supratim Bhattacharyya, Padmalaya Devi, Subrat Samantara, KP Kunhi Mohammed
  Oncology Journal of India.2020; 4(3): 145.     CrossRef
• Successful resection of pancreatic metastasis from oesophageal squamous cell carcinoma: a case report and review of the literature
  Wataru Koizumi, Minoru Kitago, Masahiro Shinoda, Hiroshi Yagi, Yuta Abe, Go Oshima, Shutaro Hori, Kenta Inomata, Hirofumi Kawakubo, Miho Kawaida, Yuko Kitagawa
  BMC Cancer.2019;[Epub]     CrossRef
• Engineered Gold Nanoshells Killing Tumor Cells: New Perspectives
  Valeria De Matteis, Mariafrancesca Cascione, Chiara C. Toma, Rosaria Rinaldi
  Current Pharmaceutical Design.2019; 25(13): 1477.     CrossRef
• An Entirely Atypical Presentation of Esophageal Squamous Cell Cancer with Pancreatic and Bone Metastases
  Eric Yoon, Yousef Nassar, Juan Tejada-Almonte, Muhammad Sohail Mansoor, Kavita Umrau, Sven Hida
  Case Reports in Gastroenterology.2019; 13(3): 423.     CrossRef
• Pancreatic Squamous Cell Carcinoma
  Seyed Hassan Abedi, Alireza Ahmadzadeh, Amir Houshang Mohammad Alizadeh
  Case Reports in Gastroenterology.2017; 11(1): 219.     CrossRef
• Esophageal Cancer Metastases to Unexpected Sites: A Systematic Review
  Osama Shaheen, Abdulaziz Ghibour, Bayan Alsaid
  Gastroenterology Research and Practice.2017; 2017: 1.     CrossRef