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Jaekwon Jung 1 Article
Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma
Yujin Lee, Jaekwang Lee, Hyunsoo Kim, Changkeun Park, Jaekwon Jung, Daejin Kim, Yun Jin Chung, Hanjun Ryu
Clin Endosc 2022;55(2):287-291.   Published online April 1, 2021
DOI: https://doi.org/10.5946/ce.2020.272
AbstractAbstract PDFPubReaderePub
Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma. An 86-year-old man was admitted with elevated liver enzymes and an increased lactate dehydrogenase level. His condition progressed to acute liver failure, but the etiology of liver failure was unclear. Esophagogastroduodenoscopy was performed to evaluate dyspepsia, which showed signs indicative of malignant melanoma. Based on the endoscopy findings and elevated liver enzyme levels, liver biopsy was performed to confirm the presence of malignant melanoma. Hepatic infiltration of malignant melanoma was observed histologically. However, massive and diffuse liver metastasis is very rare and difficult to identify on imaging studies. If the etiology of liver failure is unclear, diffuse metastatic melanoma infiltration should be considered as differential diagnosis. Early liver biopsy can help to clarify the diagnosis.

Citations

Citations to this article as recorded by  
  • HEPATOPATHY SECONDARY TO INFILTRATION BY MALIGNANT MELANOMA: DIAGNOSTIC VALUE OF LIVER BIOPSY
    Alejandro García Martínez, Álvaro Morales Prado, Jorge Martínez-Echevarría Gil-Delgado, Daniel Mateos Millán
    Revista Española de Enfermedades Digestivas.2024;[Epub]     CrossRef
  • Tumor lysis syndrome with hepatic failure- A rare presentation of undiagnosed metastatic melanoma
    Nicholas Cochran-Caggiano, Brandon Zaffuto, Ryan Dean
    JEM Reports.2023; 2(1): 100009.     CrossRef
  • Acute liver failure secondary to malignant infiltration: A single center experience
    Rocío González Grande, Ana Bravo Aranda, Inmaculada Santaella Leiva, Susana López Ortega, Miguel Jiménez Pérez
    Seminars in Oncology.2023; 50(3-5): 71.     CrossRef
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