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A Case of Colonic Mucinous Adenocarcinoma in 19-year-old Male Patient
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Mi Yeon Chung, Young Sook Park, Sang Ryul Ryu, Sang Bong Ahn, Seong Hwan Kim, Yun Ju Jo, Jun Kil Han, Jong Eun Joo
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Clin Endosc 2012;45(1):103-107. Published online March 31, 2012
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DOI: https://doi.org/10.5946/ce.2012.45.1.103
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Abstract
PDFPubReaderePub
Colorectal cancer is rare in teenagers, especially without known risk factors. Colon cancer in young age is more likely to be diagnosed at advanced-stage, to present unfavorable tumor histology such as mucinous carcinoma, and poor outcome. We report a case of sporadic mucinous adenocarcinoma of the colon in a 19-year-old male patient without any risk factors. He complained of severe left abdominal pain that developed 1 month ago. He had a distended abdomen with severe tenderness on the left lower quadrant. A distal descending colon mass causing mechanical obstruction was observed on abdominal computed tomography. Emergency colonoscopy showed a large, fungating mass obstructing the lumen at 40 cm from the anal verge. Biopsy of the colonic mass suggested a mucinous adenocarcinoma. After decompression by colonic stent, the patient was transferred to the general surgery department for left hemicolectomy. The lesion was confirmed to be a mucinous adenocarcinoma (7.0×4.5 cm). For hereditary nonpolyposis colorectal cancer evaluation, immunohistochemical staining for MLH1 and MSH2 was normal. Reverse transcription polymerase chain reaction analysis did not detect microinstability in any of the markers tested. The patient had no familial history of cancer. Mucinous adenocarcinoma has high frequencies of poor differentiation, advanced tumor stage, loss of mismatch repair gene expression, and increased MUC2 expression. A mucinous histology is considerably more frequent in children and adolescent than in adults. Adequate invasive study is also necessary for young age patients.
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Citations
Citations to this article as recorded by
- Clinicopathological features and prognosis analysis of proximal colonic mucinous adenocarcinoma
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Xiaodong Yan, Yuan Cheng, Xia Zhang, Yi Hu, Haixia Huang, Jie Ren, Boye Wen, Yuhui Yang, Keyuan Xiao, Wenqing Hu, Wei Wang Molecular Oncology.2022; 16(19): 3509. CrossRef - Biopsy sampling during self-expandable metallic stent placement in acute malignant colorectal obstruction: a narrative review
Sigrid Skov Bennedsgaard, Lene Hjerrild Iversen World Journal of Surgical Oncology.2021;[Epub] CrossRef - Mucinous colorectal adenocarcinoma: clinical pathology and treatment options
Cong Luo, Shuyi Cen, Guojun Ding, Wei Wu Cancer Communications.2019; 39(1): 1. CrossRef - Tumor Clinicopathological Characteristics and their Prognostic Value in Mucinous Colorectal Carcinoma
Cong Luo, Shuyi Cen, Jieer Ying, Xiaohong Wang, Zhixuan Fu, Peng Liu, Wei Wu, Guojun Ding Future Oncology.2019; 15(35): 4095. CrossRef - Advanced colorectal carcinoma with testicular metastasis in an adolescent: a case report
Adarsh Pratap Singh, Amit Kumar, Anita Dhar, Shipra Agarwal, Sudhir Bhimaniya Journal of Medical Case Reports.2018;[Epub] CrossRef - Bone metastasis from colon carcinoma in an 11-year-old boy: radiological features and brief review of the literature
Marco Colangeli, Carlotta Calamelli, Marco Manfrini, Tommaso Frisoni, Davide Maria Donati Skeletal Radiology.2015; 44(5): 743. CrossRef - Carcinoma of the colon in children with metastases to the duodenum: Report of two cases and management reflections
Musa Ibrahim, Adamu Ladan Mu'azu, Kabir Ibrahim Getso, Binta Jibir Wudil, Mohammad Aminu Mohammad, Ali Bala Umar, Umar Shehu Abdullahi, Kefas John Bwala, Nurlan Nurkenovich Akhparov, Aipov R. Rassulbek Journal of Pediatric Surgery Case Reports.2014; 2(3): 133. CrossRef - Colon carcinoma in childhood: review of the literature with four case reports
Gangmi Kim, Seung Hyuk Baik, Kang Young Lee, Hyuk Hur, Byung Soh Min, Chuhl Joo Lyu, Nam Kyu Kim International Journal of Colorectal Disease.2013; 28(2): 157. CrossRef - Colocolic Intussusception in an Older Child: A Rare Case Report and a Literature Review
Anupam Das, Lalmalsawma Ralte, A. S. Chawla, S. V. Arya, Anil Kumar, Ravi Saroha, Dheer Singh Kalwaniya Case Reports in Surgery.2013; 2013: 1. CrossRef
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