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Kosuke Mizukoshi 1 Article
Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids
Yuichi Tomiki, Jun Aoki, Shunsuke Motegi, Rina Takahashi, Toshiaki Hagiwara, Yu Okazawa, Kosuke Mizukoshi, Masaya Kawai, Shinya Munakata, Shun Ishiyama, Kiichi Sugimoto, Kazuhiro Sakamoto
Clin Endosc 2019;52(6):581-587.   Published online July 24, 2019
DOI: https://doi.org/10.5946/ce.2019.017
AbstractAbstract PDFPubReaderePub
Background
/Aims: Sclerotherapy with aluminum potassium sulfate and tannic acid (ALTA) has a potent effect on internal hemorrhoids. In this retrospective study, we compared the effects of endoscopic ALTA therapy and standard ALTA therapy.
Methods
We investigated patients who underwent treatment for internal hemorrhoids at our institution between 2014 and 2016. They were divided into a standard ALTA group (n=33, treated using proctoscopy) and an endoscopic ALTA group (n=48). We compared the clinical findings between the 2 groups.
Results
There were no intergroup differences in background factors. The mean ALTA dose was 21.9±7.2 mL and 17.8±3.4 mL in the standard and endoscopic ALTA groups, respectively (p<0.01). Adverse events occurred in 4 patients (12.1%) from the standard ALTA group and 6 patients (12.5%) from the endoscopic ALTA group. In both groups, the patients reported good satisfaction with the therapeutic effect at 1 month after the procedure. Hemorrhoids recurred in 2 patients (6.3%) from the standard ALTA group and 4 patients (8.3%) from the endoscopic ALTA group.
Conclusions
Endoscopic ALTA sclerotherapy is equivalent to standard ALTA therapy in terms of efficacy, adverse events, and recurrence. Therefore, it is a useful non-surgical option for patients with internal hemorrhoids who prefer a less invasive treatment.

Citations

Citations to this article as recorded by  
  • Sclerotherapy for hemorrhoidal disease: systematic review and meta-analysis
    G. Gallo, A. Picciariello, C. Armellin, E. Lori, G. Tomasicchio, G. L. Di Tanna, G. A. Santoro, M. Alharbi, S. Sorrenti, U. Grossi
    Techniques in Coloproctology.2024;[Epub]     CrossRef
  • Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy for hemorrhoidal disease: a systematic review and meta-analysis
    Vasiliki Manaki, Vangelis Bontinis, Alkis Bontinis, Argirios Giannopoulos, Ioannis Kontes, Angeliki Chorti, Kiriakos Ktenidis
    Acta Chirurgica Belgica.2024; : 1.     CrossRef
  • Sclerotherapy in Hemorrhoids
    Anling He, Mingkai Chen
    Indian Journal of Surgery.2023; 85(2): 228.     CrossRef
  • Aluminum potassium sulfate and tannic acid (ALTA) sclerotherapy complicating laparoscopic low anterior resection of rectal cancer: Case report
    Hiroka Kondo, Ryosuke Nakagawa, Tomoko Yamamoto, Shigeki Yamaguchi
    International Journal of Surgery Case Reports.2022; 98: 107543.     CrossRef
  • Laparoscopic anterior resection for rectal stenosis caused by ALTA injection for internal hemorrhoids: A case report
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    Asian Journal of Endoscopic Surgery.2021; 14(2): 271.     CrossRef
  • Rationale, new anus positioning methods, and updated protocols: Expert recommendations on cap-assisted endoscopic sclerotherapy for hemorrhoids from China Gut Conference
    Fa-Ming Zhang, Kai-Chun Wu, Jing-Nan Li, Xin Wang, Xing-Xiang He, Rong Wan, Shi-Yao Chen
    Chinese Medical Journal.2021; 134(22): 2675.     CrossRef
  • Cap-assisted endoscopic sclerotherapy for internal hemorrhoids: technique protocol and study design for a multi-center randomized controlled trial
    Xia Wu, Quan Wen, Bota Cui, Yafei Liu, Min Zhong, Yu Yuan, Lihao Wu, Xiaoyin Zhang, Yunlian Hu, Muhan Lv, Qianneng Wu, Suyu He, Yan Jin, Shuxin Tian, Rong Wan, Xin Wang, Long Xu, Jianling Bai, Guangming Huang, Guozhong Ji, Faming Zhang
    Therapeutic Advances in Gastrointestinal Endoscopy.2020; 13: 263177452092563.     CrossRef
  • Gluteal-fold flap repair of rectovaginal fistula caused by aluminum potassium sulfate hydrate-tannic acid injection for internal hemorrhoids: a case report
    Masanori Yoshimitsu, Hiroyuki Egi, Shogo Nagamatsu, Manabu Shimomura, Keishi Hakoda, Masashi Miguchi, Toshihiko Kohashi, Masazumi Okajima, Hideki Ohdan
    Surgical Case Reports.2020;[Epub]     CrossRef
  • Progress in endoscopic treatment of hemorrhoids
    Wenzhuang Ma, Jintao Guo, Fan Yang, Christoph F. Dietrich, Siyu Sun
    Journal of Translational Internal Medicine.2020; 8(4): 237.     CrossRef
  • Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid: An Effective and Less Invasive Strategy for Internal Hemorrhoids
    Naoki Muguruma, Tetsuji Takayama
    Clinical Endoscopy.2019; 52(6): 521.     CrossRef
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