Skip Navigation
Skip to contents

Clin Endosc : Clinical Endoscopy

OPEN ACCESS

Author index

Page Path
HOME > Browse Articles > Author index
Search
Noriko Okaniwa 1 Article
Predictive Factors for Intractability to Endoscopic Hemostasis in the Treatment of Bleeding Gastroduodenal Peptic Ulcers in Japanese Patients
Naotaka Ogasawara, Mari Mizuno, Ryuta Masui, Yoshihiro Kondo, Yoshiharu Yamaguchi, Kenichiro Yanamoto, Hisatsugu Noda, Noriko Okaniwa, Makoto Sasaki, Kunio Kasugai
Clin Endosc 2014;47(2):162-173.   Published online March 31, 2014
DOI: https://doi.org/10.5946/ce.2014.47.2.162
AbstractAbstract PDFPubReaderePub
Background/Aims

Despite improvements in endoscopic hemostasis and pharmacological therapies, upper gastrointestinal (UGI) ulcers repeatedly bleed in 10% to 20% of patients, and those without early endoscopic reintervention or definitive surgery might be at a high risk for mortality. This study aimed to identify the risk factors for intractability to initial endoscopic hemostasis.

Methods

We analyzed intractability among 428 patients who underwent emergency endoscopy for bleeding UGI ulcers within 24 hours of arrival at the hospital.

Results

Durable hemostasis was achieved in 354 patients by using initial endoscopic procedures. Sixty-nine patients with Forrest types Ia, Ib, IIa, and IIb at the second-look endoscopy were considered intractable to the initial endoscopic hemostasis. Multivariate analysis indicated that age ≥70 years (odds ratio [OR], 2.06; 95% confidence interval [CI], 1.07 to 4.03), shock on admission (OR, 5.26; 95% CI, 2.43 to 11.6), hemoglobin <8.0 mg/dL (OR, 2.80; 95% CI, 1.39 to 5.91), serum albumin <3.3 g/dL (OR, 2.23; 95% CI, 1.07 to 4.89), exposed vessels with a diameter of ≥2 mm on the bottom of ulcers (OR, 4.38; 95% CI, 1.25 to 7.01), and Forrest type Ia and Ib (OR, 2.21; 95% CI, 1.33 to 3.00) predicted intractable endoscopic hemostasis.

Conclusions

Various factors contribute to intractable endoscopic hemostasis. Careful observation after endoscopic hemostasis is important for patients at a high risk for incomplete hemostasis.

Citations

Citations to this article as recorded by  
  • At admission hemodynamic instability is associated with increased mortality and rebleeding rate in acute gastrointestinal bleeding: a systematic review and meta-analysis
    Edina Tari, Levente Frim, Tünde Stolcz, Brigitta Teutsch, Dániel Sándor Veres, Péter Hegyi, Bálint Erőss
    Therapeutic Advances in Gastroenterology.2023;[Epub]     CrossRef
  • Patient and endoscopic characteristics and clinical outcomes in subjects with non-variceal GI bleeding referred for transarterial embolization: a single-center experience
    Kripalini Ephraim Joseph, Aron M. Devane, Gary A. Abrams
    Abdominal Radiology.2022; 47(11): 3883.     CrossRef
  • Management von gastrointestinalen Blutungen auf der Intensivstation
    G. Braun
    Der Gastroenterologe.2020; 15(1): 34.     CrossRef
  • Novel upper gastrointestinal monitoring system to track upper gastrointestinal bleeding: A pilot study
    Chiao-Hsiung Chuang, Chien-Cheng Chen, Jhong-Han Wu, Ming-Yuan Hong, Jui-Wen Kang, Hsin-Yu Kuo, Chien-Jui Huang, Chiung-Yu Chen
    Endoscopy International Open.2020; 08(12): E1811.     CrossRef
  • Validity of the Pre-endoscopic Scoring Systems for the Prediction of the Failure of Endoscopic Hemostasis in Bleeding Gastroduodenal Peptic Ulcers
    Chikara Iino, Tadashi Shimoyama, Takasato Igarashi, Tomoyuki Aihara, Kentaro Ishii, Jyuichi Sakamoto, Hiroshi Tono, Shinsaku Fukuda
    Internal Medicine.2018; 57(10): 1355.     CrossRef
  • Clip OVESCO (OTSC) : résultats et indications en 2017
    D. Heresbach
    Acta Endoscopica.2018; 48(1-2): 26.     CrossRef
  • Endoscopic management of refractory gastrointestinal non-variceal bleeding using Histoacryl (N-butyl-2-cyanoacrylate) glue
    Damien CK Loh, Robert B Wilson
    Gastroenterology Report.2016; 4(3): 232.     CrossRef
  • Resuscitative endovascular balloon occlusion of the aorta for uncontrolled haemorrahgic shock as an adjunct to haemostatic procedures in the acute care setting
    Junya Tsurukiri, Itsurou Akamine, Takao Sato, Masatsugu Sakurai, Eitaro Okumura, Mariko Moriya, Hiroshi Yamanaka, Shoichi Ohta
    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.2016;[Epub]     CrossRef
  • Simple risk factors to predict urgent endoscopy in nonvariceal upper gastrointestinal bleeding pre-endoscopically
    Jianzong Wang, Duanming Hu, Wen Tang, Chuanyin Hu, Qin Lu, Juan Li, Jianhong Zhu, Liming Xu, Zhenyu Sui, Mingjie Qian, Shaofeng Wang, Guojian Yin
    Medicine.2016; 95(26): e3603.     CrossRef
  • First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases
    Hans-Jürgen Richter-Schrag, Torben Glatz, Christine Walker, Andreas Fischer, Robert Thimme
    World Journal of Gastroenterology.2016; 22(41): 9162.     CrossRef
  • New and emerging endoscopic haemostasis techniques
    Rebecca Palmer, Barbara Braden
    Frontline Gastroenterology.2015; 6(2): 147.     CrossRef
  • Risk factors for bleeding evaluated using the Forrest classification in Japanese patients after endoscopic submucosal dissection for early gastric neoplasm
    Hisatsugu Noda, Naotaka Ogasawara, Shinya Izawa, Tomonori Ozeki, Kenichiro Yanamoto, Noriko Okaniwa, Atsushi Tanabe, Makoto Sasaki, Kunio Kasugai
    European Journal of Gastroenterology & Hepatology.2015; 27(9): 1022.     CrossRef
  • Predictive Factors for Endoscopic Hemostasis in Patients with Upper Gastrointestinal Bleeding
    Il Kwun Chung
    Clinical Endoscopy.2014; 47(2): 121.     CrossRef
  • 6,303 View
  • 53 Download
  • 19 Web of Science
  • 13 Crossref
Close layer

Clin Endosc : Clinical Endoscopy Twitter Facebook
Close layer
TOP