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Seonghun Hong 1 Article
A Case of Endoscopic Full-Thickness Resection in a Patient with Gastric High-Grade Dysplasia Unsuitable for Endoscopic Submucosal Dissection
Jung Min Chae, Jae Young Jang, Seonghun Hong, Jung Wook Kim, Young Woon Chang
Clin Endosc 2014;47(4):353-357.   Published online July 28, 2014
DOI: https://doi.org/10.5946/ce.2014.47.4.353
AbstractAbstract PDFPubReaderePub

Gastric high-grade dysplasia is an important premalignant lesion in gastric epithelial cells and has a high possibility of transforming to adenocarcinoma. Therefore, biopsy-proven high-grade dysplasia should be treated with en bloc resection methods such as endoscopic mucosal resection or endoscopic submucosal dissection (ESD). We report the case of a 63-year-old male patient, diagnosed with gastric high-grade dysplasia at the angle and lesser curvature side of the lower body. The patient was initially treated with ESD, although histopathology subsequently showed horizontal margin involvement. Since the lesion was diffusely edematous and margins were uncertain because of the previous ESD treatment, we chose to treat the patient with laparoscopy-assisted endoscopic full-thickness resection (EFTR). EFTR is a recently developed procedure, which uses both endoscopic and laparoscopic techniques to resect the full-thickness of the tissue. The final pathologic report revealed high-grade dysplasia and a focal intramucosal carcinoma of 0.8×0.7 cm. We conclude that EFTR can be an effective alternative treatment in gastric high-grade dysplasia unsuitable for ESD.

Citations

Citations to this article as recorded by  
  • Endoscopic diagnosis and treatment of gastric dysplasia and early cancer: Current evidence and what the future may hold
    Edward Young, Hamish Philpott, Rajvinder Singh
    World Journal of Gastroenterology.2021; 27(31): 5126.     CrossRef
  • Identification and preparation of lesions suitable for endoscopic full-thickness resection
    Jeffrey Fiorenza, Pavlos Kaimakliotis
    Techniques in Gastrointestinal Endoscopy.2015; 17(3): 108.     CrossRef
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