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Takuto Hikichi 3 Articles
A multicenter comparative study of endoscopic ultrasound-guided fine-needle biopsy using a Franseen needle versus conventional endoscopic ultrasound-guided fine-needle aspiration to evaluate microsatellite instability in patients with unresectable pancreatic cancer
Tadayuki Takagi, Mitsuru Sugimoto, Hidemichi Imamura, Yosuke Takahata, Yuki Nakajima, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Yuki Sato, Hiroki Irie, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Yuko Hashimoto, Goro Shibukawa, Shigeru Marubashi, Takuto Hikichi, Hiromasa Ohira
Clin Endosc 2023;56(1):107-113.   Published online January 16, 2023
DOI: https://doi.org/10.5946/ce.2022.019
AbstractAbstract PDFPubReaderePub
Background
/Aims: Immune checkpoint blockade has recently been reported to be effective in treating microsatellite instability (MSI)-high tumors. Therefore, sufficient sampling of histological specimens is necessary in cases of unresectable pancreatic cancer (UR-PC). This multicenter study investigated the efficacy of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) using a Franseen needle for MSI evaluation in patients with UR-PC.
Methods
A total of 89 patients with UR-PC who underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or EUS-FNB using 22-G needles at three hospitals in Japan (2018–2021) were enrolled. Fifty-six of these patients (FNB 23 and FNA 33) were followed up or evaluated for MSI. Patient characteristics, UR-PC data, and procedural outcomes were compared between patients who underwent EUS-FNB and those who underwent EUS-FNA.
Results
No significant difference in terms of sufficient tissue acquisition for histology was observed between patients who underwent EUS-FNB and those who underwent EUS-FNA. MSI evaluation was possible significantly more with tissue samples obtained using EUS-FNB than with tissue samples obtained using EUS-FNA (82.6% [19/23] vs. 45.5% [15/33], respectively; p<0.01). In the multivariate analysis, EUS-FNB was the only significant factor influencing the possibility of MSI evaluation.
Conclusions
EUS-FNB using a Franseen needle is desirable for ensuring sufficient tissue acquisition for MSI evaluation.

Citations

Citations to this article as recorded by  
  • Oil blotting paper for formalin fixation increases endoscopic ultrasound‐guided tissue acquisition‐collected sample volumes on glass slides
    Takuo Yamai, Kenji Ikezawa, Yusuke Seiki, Ko Watsuji, Yasuharu Kawamoto, Takeru Hirao, Kazuma Daiku, Shingo Maeda, Makiko Urabe, Yugo Kai, Ryoji Takada, Kaori Mukai, Tasuku Nakabori, Hiroyuki Uehara, Sayoko Tsuzaki, Ayumi Ryu, Satoshi Tanada, Shigenori Na
    Cancer Medicine.2024;[Epub]     CrossRef
  • Lymphadenopathy Tissue Sampling by EUS-Guided Fine-Needle Biopsy Contributes to Meeting the Conditions for Genomic Profiling
    Mitsuru Sugimoto, Tadayuki Takagi, Rei Suzuki, Naoki Konno, Hiroyuki Asama, Yuki Sato, Hiroki Irie, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira
    Journal of Clinical Gastroenterology.2024;[Epub]     CrossRef
  • MSI-H Detection by ddPCR in Endoscopic Ultrasound Fine Needle Biopsy (EUS-FNB) from Pancreatic Ductal Adenocarcinoma
    Maria Assunta Piano, Elisa Boldrin, Lidia Moserle, Nicoletta Salerno, Dalila Fanelli, Giulia Peserico, Maria Raffaella Biasin, Giovanna Magni, Veronica Varano, Giorgia Zalgelli, Vasileios Mourmouras, Antonio Rosato, Antonio Scapinello, Alberto Fantin, Mat
    International Journal of Molecular Sciences.2024; 25(20): 11090.     CrossRef
  • 2,671 View
  • 146 Download
  • 2 Web of Science
  • 3 Crossref
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Aerosol extractor for COVID-2019 prevention during endoscopic procedure
Takuto Hikichi, Tsunetaka Kato, Ryoichiro Kobashi, Minami Hashimoto, Jun Nakamura
Clin Endosc 2022;55(6):815-818.   Published online August 29, 2022
DOI: https://doi.org/10.5946/ce.2022.025
PDFSupplementary MaterialPubReaderePub

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  • Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China
    Yanhai Wang, Guohui Yu, Jingru Shi, Xiaqing Zhang, Jianxin Huo, Meng Li, Jiaxi Chen, Liyuan Yu, Yan Li, Zhiliang Han, Jianwen Zhang, Xuna Ren, Yujie Wang, Wu Yuntana
    BMC Infectious Diseases.2024;[Epub]     CrossRef
  • 2,991 View
  • 124 Download
  • 1 Web of Science
  • 1 Crossref
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A Novel Endoscopic Mouthpiece for COVID-19 Prevention
Takuto Hikichi, Nakamura Jun, Koichi Hamada, Daiki Nemoto
Clin Endosc 2022;55(1):160-162.   Published online October 15, 2021
DOI: https://doi.org/10.5946/ce.2021.172
PDFPubReaderePub

Citations

Citations to this article as recorded by  
  • Impact of the COVID‐19 pandemic on the performance of endoscopy in the Tohoku region of Japan
    Katsunori Iijima, Tamotsu Matsuhashi, Yosuke Shimodaira, Tatsuya Mikami, Tetsuro Yoshimura, Shunichi Yanai, Norihiko Kudara, Tsuyotoshi Tsuji, Hiro‐o Matsushita, Hiroyuki Watanabe, Tomoyuki Koike, Katsuaki Kato, Yasuhiko Abe, Nakao Shirahata, Takuto Hikic
    DEN Open.2024;[Epub]     CrossRef
  • A Follow-up Report on the Diagnosis of Gastrointestinal Cancer during the COVID-19 Pandemic in Akita Prefecture, Japan in 2021
    Katsunori Iijima, Yosuke Shimodaira, Kenta Watanabe, Shigeto Koizumi, Tamotsu Matsuhashi, Mario Jin, Masahito Miura, Kengo Onochi, Kiyonori Yamai, Yuko Fujishima, Takuma Ajimine, Hidehiko Tsuda, Tsuyotoshi Tsuji, Hiro-o Matsushita, Yohei Horikawa, Takahir
    The Tohoku Journal of Experimental Medicine.2023; 259(4): 301.     CrossRef
  • A Novel Aerosol-Exposure Protection Mask for Patients During Upper Endoscopy
    Soo-Jeong Cho
    Clinical Endoscopy.2022; 55(2): 208.     CrossRef
  • Simple and innovative methods of minimizing risk of aerosol generation during endoscopy
    Sumitro Kosasih, Adli Metussin, Norwani Basir, Vui Heng Chong
    Clinical Endoscopy.2022; 55(3): 470.     CrossRef
  • Aerosol extractor for COVID-2019 prevention during endoscopic procedure
    Takuto Hikichi, Tsunetaka Kato, Ryoichiro Kobashi, Minami Hashimoto, Jun Nakamura
    Clinical Endoscopy.2022; 55(6): 815.     CrossRef
  • 4,576 View
  • 141 Download
  • 5 Web of Science
  • 5 Crossref
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