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Tayyaba Mohammad 1 Article
Comparing palliative treatment options for cholangiocarcinoma: photodynamic therapy vs. radiofrequency ablation
Tayyaba Mohammad, Michel Kahaleh
Clin Endosc 2022;55(3):347-354.   Published online May 17, 2022
DOI: https://doi.org/10.5946/ce.2021.274
AbstractAbstract PDFPubReaderePub
Referral to an endoscopist is often done once curative resection is no longer an option for cholangiocarcinoma management. In such cases, palliation has become the main objective of the treatment. Photodynamic therapy and radiofrequency ablation can be performed to achieve palliation, with both procedures associated with improved stent patency and survival. Despite the greatly increased cost and association with photosensitivity, photodynamic therapy allows transmission to the entire biliary tree. In contrast, radiofrequency ablation is cheaper and faster to apply but requires intraductal contact. This paper reviews both modalities and compares their efficacy and safety for bile duct cancer palliation.

Citations

Citations to this article as recorded by  
  • Current interventional options for palliative care for patients with advanced-stage cholangiocarcinoma
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    World Journal of Clinical Oncology.2024; 15(3): 381.     CrossRef
  • Endoskopisch gesteuerte Diagnostik und Therapie von Cholangiokarzinomen
    Ulrike Denzer, Alexander Dechêne
    Die Gastroenterologie.2023; 18(1): 16.     CrossRef
  • Recent Updates on Local Ablative Therapy Combined with Chemotherapy for Extrahepatic Cholangiocarcinoma: Photodynamic Therapy and Radiofrequency Ablation
    Tadahisa Inoue, Masashi Yoneda
    Current Oncology.2023; 30(2): 2159.     CrossRef
  • Role of radiofrequency ablation in advanced malignant hilar biliary obstruction
    Mamoru Takenaka, Tae Hoon Lee
    Clinical Endoscopy.2023; 56(2): 155.     CrossRef
  • Impact of endobiliary radiofrequency ablation on survival of patients with unresectable cholangiocarcinoma: a narrative review
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  • Thermal ablative therapies in the gastrointestinal tract
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    Current Opinion in Gastroenterology.2023; 39(5): 370.     CrossRef
  • Photodynamic Therapy: From the Basics to the Current Progress of N-Heterocyclic-Bearing Dyes as Effective Photosensitizers
    Eurico Lima, Lucinda V. Reis
    Molecules.2023; 28(13): 5092.     CrossRef
  • Balloon‐assisted laser application for endoscopic treatment of biliary stricture
    Seonghee Lim, Van Gia Truong, Seok Jeong, Jiho Lee, Byeong‐il Lee, Hyun Wook Kang
    Lasers in Surgery and Medicine.2023; 55(10): 912.     CrossRef
  • Emerging Systemic Therapies in Advanced Unresectable Biliary Tract Cancer: Review and Canadian Perspective
    Vincent C. Tam, Ravi Ramjeesingh, Ronald Burkes, Eric M. Yoshida, Sarah Doucette, Howard J. Lim
    Current Oncology.2022; 29(10): 7072.     CrossRef
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