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Nonvariceal upper gastrointestinal (GI) bleeding is one of the most common reasons for hospitalization and a major cause of morbidity and mortality worldwide. Recently developed endoscopic devices and supporting apparatuses can achieve endoscopic hemostasis with greater safety and efficiency. With these advancements in technology and technique, gastroenterologists should have no concerns regarding the management of acute upper GI bleeding, provided that they are well prepared and trained. However, when endoscopic hemostasis fails, endoscopy should not be continued. Rather, endoscopists should refer patients to radiologists and surgeons without any delay for evaluation regarding the appropriateness of emergency interventional radiology or surgery.

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Mallory-Weiss tearing (MWT) is a common cause of non-variceal upper gastrointestinal bleeding. Although the majority of patients with bleeding MWT require no intervention other than hemodynamic supports, spectrum of MWT is wide, and the condition sometimes results in a fatal outcome. Endoscopic management to stop the bleeding may be required during the index endoscopy, especially in those with active bleeding or stigmata of recurrent bleeding. Most commonly used endoscopic treatment for actively bleeding MWT is injection therapy, argon plasma coagulation, hemoclip placement, and band ligation. Selection of the optimal endoscopic hemostasis depends on the physician's ability and patient's clinical status.

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A Dieulafoy's lesion is a vascular abnormality consisting of a large caliber-persistent tortuous submucosal artery. A small mucosal defect with the eruption of this protruding vessel can cause bleeding. In fact, a Dieulafoy's lesion is a relatively rare but potentially life-threatening condition. It accounts for 1% to 2% of cases of acute gastrointestinal bleeding. Although there is no consensus on the treatment of Dieulafoy's lesions; treatment options depend on the mode of presentation, site of the lesion, and available expertise. Endoscopic therapy is usually successful in achieving primary hemostasis, with hemostasis success rates reaching 75% to 100%. Although various therapeutic endoscopic methods are used to control bleeding in Dieulafoy's lesions, the best method for endoscopic intervention is not clear. Combination endoscopic therapy is known to be superior to monotherapy because of a lower rate of recurrent bleeding. In addition, mechanical therapies including hemostatic clipping and endoscopic band ligation are more effective and successful in controlling bleeding than other endoscopic methods. Advances in endoscopic techniques have reduced mortality in patients with Dieulafoy's lesion-from 80% to 8%-and consequently, the need for surgical intervention has been reduced. Currently, surgical intervention is used for cases that fail therapeutic endoscopic or angiographic interventions.

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Tumor bleeding is not a rare complication in patients with inoperable gastric cancer. Endoscopy has important roles in the diagnosis and primary treatment of tumor bleeding, similar to its roles in other non-variceal upper gastrointestinal bleeding cases. Although limited studies have been performed, endoscopic therapy has been highly successful in achieving initial hemostasis. One or a combination of endoscopic therapy modalities, such as injection therapy, mechanical therapy, or ablative therapy, can be used for hemostasis in patients with endoscopic stigmata of recent hemorrhage. However, rebleeding after successful hemostasis with endoscopic therapy frequently occurs. Endoscopic therapy may be a treatment option for successfully controlling this rebleeding. Transarterial embolization or palliative surgery should be considered when endoscopic therapy fails. For primary and secondary prevention of tumor bleeding, proton pump inhibitors can be prescribed, although their effectiveness to prevent bleeding remains to be investigated.

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Video capsule endoscopy (VCE) is an ingestible video camera that transmits high-quality images of the small intestinal mucosa. This makes the small intestine more readily accessible to physicians investigating the presence of small bowel disorders, such as Crohn's disease (CD). Although VCE is frequently performed in Korea, there are no evidence-based guidelines on the appropriate use of VCE in the diagnosis of CD. To provide accurate information and suggest correct testing approaches for small bowel diseases, the Korean Gut Image Study Group, part of the Korean Society of Gastrointestinal Endoscopy, developed guidelines on VCE. Teams were set up to develop guidelines on VCE. Four areas were selected: diagnosis of obscure gastrointestinal bleeding, small bowel preparation for VCE, diagnosis of CD, and diagnosis of small bowel tumors. Three key questions were selected regarding the role of VCE in CD. In preparing these guidelines, a systematic literature search, evaluation, selection, and meta-analysis were performed. After writing a draft of the guidelines, the opinions of various experts were solicited before producing the final document. These guidelines are expected to play a role in the diagnosis of CD. They will need to be updated as new data and evidence become available.

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  Diagnostic Cytopathology.2024;[Epub]     CrossRef
• Anaplastic large cell lymphoma of adrenal gland—An endoscopic ultrasound enigma
  Chinmay Vishwanath Hegde, Anudeep Katrevula, Balasaheb Wanve, Nageshwar Reddy Duvvur
  Indian Journal of Gastroenterology.2024;[Epub]     CrossRef
• Research Progress of Ultrasonography in Adrenal Tumors
  鑫媛 贺
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• Adrenal gland fine needle aspiration: a multi-institutional analysis of 139 cases
  Kimberly S. Point du Jour, Yazeed Alwelaie, Arlixer Coleman, Talaat Tadros, Ritu Aneja, Michelle D. Reid
  Journal of the American Society of Cytopathology.2021; 10(2): 168.     CrossRef
• Diagnostic utility of cytology smears and cell block in adrenal lesions
  Sriranjan Mukherjee, Moumita Sengupta, Ram Narayan Das, Uttara Chatterjee, Banhisikha Kanjilal, Keya Basu, Anish Kar, Akash Mondal, Satinath Mukhopadhyay
  Diagnostic Cytopathology.2020; 48(11): 1003.     CrossRef
• EUS‐FNA, ancillary studies and their clinical utility in patients with mediastinal, pancreatic, and other abdominal lesions
  Muhammad Saqib, Maheen Maruf, Sehar Bashir, Shafqat Mehmood, Noreen Akhter, Muhammed Aasim Yusuf, Asif Loya
  Diagnostic Cytopathology.2020; 48(11): 1058.     CrossRef
• Fine‐needle aspiration of adrenal lesions: A 20‐year single institution experience with comparison of percutaneous and endoscopic ultrasound guided approaches
  Aaron G. Novotny, Jordan P. Reynolds, Akeesha A. Shah, Amit Bhatt, Prabhleen Chahal, Erick M. Remer, Tyler Stevens, Stephen Gmitro, Charles D. Sturgis
  Diagnostic Cytopathology.2019; 47(10): 986.     CrossRef
• Adrenal biopsy: performance and use
  Catherine D. Zhang, Danae A. Delivanis, Patrick W. Eiken, Thomas D. Atwell, Irina Bancos
  Minerva Endocrinologica.2019;[Epub]     CrossRef
• Endoscopic ultrasound-guided fine-needle aspiration of enlarged adrenals in patients with pyrexia of unknown origin: A single-center experience of 52 cases
  Rinkesh K. Bansal, Narendra S. Choudhary, Saurabh K. Patle, Amit Agarwal, Gagandeep Kaur, Haimanti Sarin, Rajesh Puri
  Indian Journal of Gastroenterology.2018; 37(2): 108.     CrossRef
• Transesophageal approach to lung, adrenal biopsy and fiducial placement using endoscopic ultrasonography (EUS): An interventional pulmonology experience. Initial experience of the UCSF-FRETOC (fresno tracheobronchial & oesophageal center) study group
  Faye M. Pais, Raj A. Shah, Jose J. Vempilly, Sneha Gullapalli, Daya Upadhyay, Michael Peterson, Moishe Liberman, Pravachan Hegde
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• First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma
  Shaunak R. Mulani, Patrick Stoner, Alexander Schlachterman, Hans K. Ghayee, Li Lu, Anand Gupte
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• Lipomatous tumours in adrenal gland: WHO updates and clinical implications
  Alfred King-yin Lam
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• A Twenty-First-Century Perspective of Disseminated Histoplasmosis in India: Literature Review and Retrospective Analysis of Published and Unpublished Cases at a Tertiary Care Hospital in North India
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  European Journal of Endocrinology.2016; 175(2): R65.     CrossRef
• Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors
  Martin Fassnacht, Wiebke Arlt, Irina Bancos, Henning Dralle, John Newell-Price, Anju Sahdev, Antoine Tabarin, Massimo Terzolo, Stylianos Tsagarakis, Olaf M Dekkers
  European Journal of Endocrinology.2016; 175(2): G1.     CrossRef
• Role of endoscopic ultrasound in non-small cell lung cancer
  Sumit Bhatia, Rajesh Puri
  International Journal of Gastrointestinal Intervention.2016; 5(3): 187.     CrossRef
• Is Endoscopic Ultrasonography-Guided Fine Needle Aspiration Trailblazing in Tissue Sampling of Adrenal Masses?
  Tae Hyeon Kim
  Clinical Endoscopy.2015; 48(2): 94.     CrossRef

Peripheral facial nerve palsy (FNP) is a mononeuropathy that affects the peripheral part of the facial nerve. Primary causes of peripheral FNP remain largely unknown, but detectable causes include systemic infections (viral and others), trauma, ischemia, tumor, and extrinsic compression. Peripheral FNP in relation to extrinsic compression has rarely been described in case reports. Here, we report a case of a 71-year-old man who was diagnosed with peripheral FNP following endoscopic submucosal dissection. This case is the first report of the development of peripheral FNP in a patient undergoing therapeutic endoscopy. We emphasize the fact that physicians should be attentive to the development of peripheral FNP following therapeutic endoscopy.

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• Drooping After Scoping: A Rare Case of Peripheral Facial Nerve Palsy After RoutineEsophagogastroduodenoscopy
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  ACG Case Reports Journal.2022; 9(1): e00687.     CrossRef
• A Case Report of a Patient with Facial Nerve Palsy that Occurred Consecutively on Both Sides After Gastroscopy
  Hyo-won Jin, Sol Jeong, Jeong-rim Bak, Ji-hyun Hwang, Jong-min Yun, Byung-soon Moon
  The Journal of Internal Korean Medicine.2022; 43(5): 989.     CrossRef
• A Rare Complication of Spine Surgery: Case Report of Peripheral Facial Palsy
  Serdar Demiröz, Ismail E. Ketenci, Hakan S. Yanik, Sevki Erdem
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• Facial palsy following cochlear implantation
  Farid Alzhrani, Thomas Lenarz, Magnus Teschner
  European Archives of Oto-Rhino-Laryngology.2016; 273(12): 4199.     CrossRef

Rhus-related illnesses in Korea are mostly caused by ingestion of parts of the Rhus tree. Contact dermatitis occurrence after ingestion of Rhus-related food is very common in Korea. However, Rhus-related gastrointestinal disease is very rare. Herein, we present a case of eosinophilic gastroenteritis caused by Rhus ingestion. A 75-year-old woman was admitted with hematemesis and hematochezia after Rhus extract ingestion. Routine laboratory tests revealed leukocytosis without eosinophilia. Endoscopy showed friable and granular mucosal changes with touch bleeding in the second portion of the duodenum. Abdominal computed tomography revealed edematous wall thickening of the duodenum and proximal jejunal loops. Patch testing with Rhus extracts showed a strong positive reaction, suggesting Rhus as the allergen. Her symptoms improved after avoidance of the allergen.

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• Systemic contact dermatitis induced by Rhus allergens in Korea: exercising caution in the consumption of this nutritious food
  S. J. Park, J. W. Park, K. Y. Park, K. Li, S. J. Seo, B. J. Kim, K. H. Yoo
  Clinical and Experimental Dermatology.2021; 46(2): 324.     CrossRef
• Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease
  Elif Ozdogan, Latife Doganay Caglayan, Ozlem Mizikoglu, Cigdem Arikan
  JPGN Reports.2020; 1(2): e017.     CrossRef
• Severe upper gastrointestinal bleeding due to eosinophilic gastritis
  Valentín Gonzalez-Canalizo, Nerea Segues, Andrea Medina, Silvia Torrente, Vanessa Aguilar-Gama, Paula Ortega, Luis Bujanda
  Gastroenterología y Hepatología.2019; 42(5): 307.     CrossRef
• Severe upper gastrointestinal bleeding due to eosinophilic gastritis
  Valentín Gonzalez-Canalizo, Nerea Segues, Andrea Medina, Silvia Torrente, Vanessa Aguilar-Gama, Paula Ortega, Luis Bujanda
  Gastroenterología y Hepatología (English Edition).2019; 42(5): 307.     CrossRef

"Cat scratch colon" is a gross finding characterized by hemorrhagic mucosal scratches on colonoscopy. It is usually associated with a normal colon and is rarely associated with collagenous colitis. In a previous report, cat scratch colon was noted in the cecum and ascending colon, but has also been observed in the distal transverse colon. The patient in this study was also diagnosed with ischemic colitis that may have played a role in the development of cat scratch colon.

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• An unexpected finding of cat scratch colon in a screening colonoscopy
  Natalia Mora Cuadrado, Noelia Alcaide Suárez, Beatriz Antolín Melero, Beatriz Burgueño Gómez, Miguel Durà Gil, Luis Ignacio Fernández Salazar, José Manuel González Hernández
  Gastroenterología y Hepatología (English Edition).2019; 42(3): 172.     CrossRef
• Hallazgo inesperado de colon en arañazo de gato en una colonoscopia de cribado
  Natalia Mora Cuadrado, Noelia Alcaide Suárez, Beatriz Antolín Melero, Beatriz Burgueño Gómez, Miguel Durà Gil, Luis Ignacio Fernández Salazar, José Manuel González Hernández
  Gastroenterología y Hepatología.2019; 42(3): 172.     CrossRef