Clinical Endoscopy

Case Report

Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis: Hee Kyung Kim, Weon Jin Ko, Chang-Il Kwon, Ga Won Song, In Kyun Yoo, Ji Hyun Song, Hak Su Kim, Joo Young Cho; Clin Endosc 2019;52(5):502-505. Published online May 14, 2019; DOI: https://doi.org/10.5946/ce.2018.176

Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here, we present the preliminary results of endoscopic submucosal dissection followed by concurrent chemoradiotherapy for early esophageal cancer with a high risk of lymph node metastasis. From May 2006 to January 2014, six patients underwent concurrent chemoradiotherapy after endoscopic submucosal dissection with a median follow-up period of 63 months. No complications were encountered during concurrent chemoradiotherapy. Although local recurrence did not occur in all patients, two patients were diagnosed with metachronous cancer. Overall, the survival rate was 100%. Thus, endoscopic submucosal dissection followed by concurrent chemoradiotherapy may be a feasible treatment for early esophageal cancer in patients with a high risk of lymph node metastasis. Future prospective large-scale studies are warranted to confirm our results.

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Citations to this article as recorded by

Unveiling Therapeutic Targets for Esophageal Cancer: A Comprehensive Review
Rakesh Acharya, Ananya Mahapatra, Henu Kumar Verma, L. V. K. S. Bhaskar
Current Oncology.2023; 30(11): 9542. CrossRef
Editorial “Discrepancy Between the Clinical and Final Pathological Findings of Lymph Node Metastasis in Superficial Esophageal Cancer”
Rian M. Hasson, Joseph D. Phillips
Annals of Surgical Oncology.2019; 26(9): 2662. CrossRef

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Review

Evaluation and Endoscopic Management of Esophageal Submucosal Tumor: Weon Jin Ko, Ga Won Song, Joo Young Cho; Clin Endosc 2017;50(3):250-253. Published online November 7, 2016; DOI: https://doi.org/10.5946/ce.2016.109

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Submucosal tumors (SMTs) originate from tissues that constitute the submucosal layer and muscularis propria, and are covered by normal mucosa. Esophageal SMTs are rare, accounting for <1% of all esophageal tumors. However, the recent widespread use of endoscopy has led to a rapid increase in incidental detection of SMTs in Korea. Esophageal SMTs are benign in ≥90% of cases, but the possibility of malignancies such as gastrointestinal stromal tumor and malignant leiomyosarcoma still exists. Therefore, patients undergo resection in the presence of symptoms or the possibility of a malignant tumor. For resection of esophageal SMTs, surgical resection was the only option available in case of possible malignancy, but minimally invasive surgery by endoscopic resection is becoming more preferable to surgical resection with the development of endoscopic ultrasonography, endoscopic techniques, and other devices.

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Mohammad Alomari, Daniel Knewitz, Rocio Castillo Larios, Jamii St. Julien, Mathew Thomas, Enrique F. Elli, Steven P. Bowers
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The Korean Journal of Internal Medicine.2024; 39(4): 603. CrossRef
Ligation-assisted endoscopic submucosal resection following unroofing technique for small esophageal subepithelial lesions originating from the muscularis propria
Quan Lu, Quan-Zhou Peng, Jun Yao, Li-Sheng Wang, De-Feng Li
World Journal of Gastroenterology.2024; 30(32): 3748. CrossRef
Advanced Esophageal Endoscopy
Kyoungwon Jung, Rebecca M. Haug, Andrew Y. Wang
Gastroenterology Clinics of North America.2024; 53(4): 603. CrossRef
Endoscopic treatment of subepithelial tumors of the esophagus and cardia
A. A. Smirnov, Ya. V. Ruchkina, M. M. Saadulaeva, E. V. Blinov, R. A. Karpova, A. Yu. Korolko
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Mana Matsuoka, Katsumasa Kobayashi, Yukito Okura, Takahito Nozaka, Ayako Sato, Masato Yauchi, Taichi Matsumoto, Yohei Furumoto, Takao Horiuchi, Toru Asano
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Shibo Song, Xiaolong Feng, Xudong Liu, Guiqi Wang, Liyan Xue
Medicina.2022; 58(12): 1804. CrossRef
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Yue Zhang, Jing Wen, Shuxian Zhang, Xuyang Liang, Ling Ren, Lu Wang, Yunliang Sun, Shouying Li, Kun Wang, Shengxiang Lv, Xiao Qiao
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Role of endoscopic ultrasound in anticancer therapy: Current evidence and future perspectives
Andre Bratanic, Dorotea Bozic, Antonio Mestrovic, Dinko Martinovic, Marko Kumric, Tina Ticinovic Kurir, Josko Bozic
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Left atrial appendage thrombus detected by transesophageal examination with linear endoscopic ultrasound
Kenji Ikezawa, Minoru Shigekawa, Kaoruko Sengoku, Teppei Yoshioka, Ryotaro Sakamori, Yasushi Sakata, Tetsuo Takehara
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Tomoaki Aoki, Tetsu Nakamura, Taro Oshikiri, Hiroshi Hasegawa, Masashi Yamamoto, Yoshiko Matsuda, Shingo Kanaji, Kimihiro Yamashita, Takeru Matsuda, Yasuo Sumi, Satoshi Suzuki, Yoshihiro Kakeji
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Soon Young Kim, Sang Kil Lee, Hyang Joo Ryu
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2017; 17(3): 144. CrossRef

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17 Web of Science
16 Crossref

Case Reports

Double-Scope Peroral Endoscopic Myotomy (POEM) for Esophageal Achalasia: The First Trial of a New Double-Scope POEM: Hee Jin Hong, Ga Won Song, Weon Jin Ko, Won Hee Kim, Ki Baik Hahm, Sung Pyo Hong, Joo Young Cho; Clin Endosc 2016;49(4):383-386. Published online March 15, 2016; DOI: https://doi.org/10.5946/ce.2015.108

Abstract PDF PubReader ePub

With the accumulation of clinical trials demonstrating its efficacy and safety, peroral endoscopic myotomy (POEM) has emerged as a less invasive treatment option for esophageal achalasia compared with laparoscopic Heller myotomy. However, the difficulty in determining the exact extent of myotomy, a critical factor associated with the success and safety of the procedure, remains a limitation. Although the various endoscopic landmarks and ancillary techniques have been applied, none of these has been proven sufficient. As a solution for this limitation, the double-scope POEM technique with a second endoscope to assure the exact length of the submucosal tunnel has been applied since 2014. Before double-scope POEM was introduced, the second endoscope was applied only to confirm the accuracy of the procedure. In the present study, we performed double-scope POEM in the treatment of esophageal achalasia through a novel procedure of simultaneous application of the second endoscope to assist in the conventional POEM procedure.

Citations

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Per-oral endoscopic myotomy (POEM) in achalasia: why length matters
Anthony J. Kang, John E. Pandolfino, A. Aziz Aadam
Expert Review of Gastroenterology & Hepatology.2026; 20(2): 93. CrossRef
Per Oral Endoscopic Myotomy – How Do I Do It?
Nirmaljeet Singh Malhi, Jasmeet Singh Dhingra
Journal of Digestive Endoscopy.2026;[Epub] CrossRef
Use of intraoperative fluoroscopy to reduce post–peroral endoscopic myotomy reflux: a proof-of-concept study
Erica Loon, Rahul Karna, Amir Sultan Seid, Mohammad Bilal, Nabeel Azeem
iGIE.2025; 4(3): 213. CrossRef
A novel anatomically guided strategy for evaluation of sufficient myotomy during peroral endoscopic myotomy in patients with achalasia
Ahmad Madkour, Amr Elfouly, Osama Elnahas, Ningli Chai, Muhammad Elzahaby, Hosam Hamed, Hassan Atalla
VideoGIE.2025; 10(9): 452. CrossRef
Clinical Course of Blown‐Out Myotomy After Peroral Endoscopic Myotomy in Patients With Achalasia‐Related Esophageal Motility Disorders
Hiroshi Tanabe, Hirofumi Abe, Shinwa Tanaka, Hiroya Sakaguchi, Chise Ueda, Tatsuya Nakai, Hitomi Hori, Shinya Hoki, Satoshi Urakami, Tetsuya Yoshizaki, Masato Kinoshita, Fumiaki Kawara, Takashi Toyonaga, Yuzo Kodama
Digestive Endoscopy.2025; 37(12): 1323. CrossRef
Gastroesophageal reflux after per-oral endoscopic myotomy: Management literature
Ahmed Tawheed, Ibrahim Halil Bahcecioglu, Mehmet Yalniz, Mohamed El-Kassas
World Journal of Gastroenterology.2024; 30(23): 2947. CrossRef
Peroral Endoscopic Myotomy (POEM) in Children
Ali A. Mencin, Amrita Sethi, Monique T. Barakat, Diana G. Lerner
Journal of Pediatric Gastroenterology and Nutrition.2022; 75(3): 231. CrossRef
Per-oral endoscopic myotomy (POEM) for a sigmoid type of achalasia: short-term outcomes and changes in the esophageal angle
Shota Maruyama, Yusuke Taniyama, Tadashi Sakurai, Makoto Hikage, Chiaki Sato, Kai Takaya, Takuro Konno, Takeshi Naitoh, Michiaki Unno, Takashi Kamei
Surgical Endoscopy.2020; 34(9): 4124. CrossRef
Characteristics of a Subset of Achalasia With Normal Integrated Relaxation Pressure
Eunju Kim, In Kyung Yoo, Dong Keon Yon, Joo Young Cho, Sung Pyo Hong
Journal of Neurogastroenterology and Motility.2020; 26(2): 274. CrossRef
Feasibility of using an led-probe in third-space endoscopy: a clinical study
Oscar Víctor Hernández Mondragón, Raúl Zamarripa Mottú, Omar Solórzano Pineda, Raúl Alberto Gutierrez Aguilar, Luís Fernando García Contreras
BMC Gastroenterology.2020;[Epub] CrossRef
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Anastassios C. Manolakis, Haruhiro Inoue, Akiko Ueno, Yuto Shimamura
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Treatment of Achalasia with Per-Oral Endoscopic Myotomy: Analysis of 50 Consecutive Patients
Erica D. Kane, David J. Desilets, Donna Wilson, Marc Leduc, Vikram Budhraja, John R. Romanelli
Journal of Laparoendoscopic & Advanced Surgical Techniques.2018; 28(5): 514. CrossRef
Two penetrating vessels as a novel indicator of the appropriate distal end of peroral endoscopic myotomy
Shinwa Tanaka, Fumiaki Kawara, Takashi Toyonaga, Haruhiro Inoue, Robert Bechara, Namiko Hoshi, Hirohumi Abe, Yoshiko Ohara, Tsukasa Ishida, Yoshinori Morita, Eiji Umegaki
Digestive Endoscopy.2018; 30(2): 206. CrossRef

10,409 View
118 Download
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13 Crossref

Communicating Tubular Esophageal Duplication Combined with Bronchoesophageal Fistula: Ju Hwan Kim, Chang-Il Kwon, Ji Young Rho, Sang Woo Han, Ji Su Kim, Suk Pyo Shin, Ga Won Song, Ki Baik Hahm; Clin Endosc 2016;49(1):81-85. Published online January 28, 2016; DOI: https://doi.org/10.5946/ce.2016.49.1.81

Abstract PDF PubReader ePub

Esophageal duplication (ED) is rarely diagnosed in adults and is usually asymptomatic. Especially, ED that is connected to the esophagus through a tubular communication and combined with bronchoesophageal fistula (BEF) is extremely rare and has never been reported in the English literature. This condition is very difficult to diagnose. Although some combinations of several modalities, such as upper gastrointestinal endoscopy, esophagography, computed tomography, magnetic resonance imaging, and endoscopic ultrasonography, can be used for the diagnosis, the results might be inconclusive. Here, we report on a patient with communicating tubular ED that was incidentally diagnosed on the basis of endoscopy and esophagography during the postoperational evaluation of BEF.

Citations

Citations to this article as recorded by

Reconstruction of Adult Tubular Esophageal Duplication with Supraclavicular Artery Island Flap: A Rare Case Presentation
Xin Yang, Zheng Jiang, Jun Liu, Fei Chen
Ear, Nose & Throat Journal.2025;[Epub] CrossRef
A Rare Case of Esophageal Duplication: A Case Report and Literature Review
Soufiane Berrichou, Aurélia Bachard, Ana Giordano, Oana Toca, Jean-François Lecompte, Valérie Triolo, Sonanda Bailleux
European Journal of Medical and Health Sciences.2025; 7(3): 81. CrossRef
Tubular Duplication of the Esophagus in a Newborn, Treated by Thoracoscopy
Igor Khvorostov, Alexey Gusev, Abdumanap Alkhasov, Sergey Yatsyk, Elena D'yakonova
European Journal of Pediatric Surgery Reports.2022; 10(01): e49. CrossRef
Endoscopic septum division of tubular esophageal duplication in two children and systematic review
Rahşan Özcan, Ali Ekber Hakalmaz, Şenol Emre, Ayşe Karagöz, Çiğdem Tütüncü, Sebuh Kuruğoğlu, Gonca Topuzlu Tekant
Pediatric Surgery International.2022; 38(11): 1525. CrossRef
Endoscopic management of a tubular esophageal duplication in a young adult
Pietro Familiari, Rosario Landi, Francesca Mangiola, Camilla Vittoria Vita, Guido Costamagna
VideoGIE.2020; 5(10): 455. CrossRef
Esophageal duplication and congenital esophageal stenosis
A. Francois Trappey, Shinjiro Hirose
Seminars in Pediatric Surgery.2017; 26(2): 78. CrossRef

12,620 View
105 Download
4 Web of Science
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