Review
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International Digestive Endoscopy Network consensus on the management of antithrombotic agents in patients undergoing gastrointestinal endoscopy
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Seung Joo Kang
, Chung Hyun Tae
, Chang Seok Bang
, Cheol Min Shin
, Young-Hoon Jeong
, Miyoung Choi
, Joo Ha Hwang
, Yutaka Saito
, Philip Wai Yan Chiu, Rungsun Rerknimitr
, Christopher Khor
, Vu Van Khien
, Kee Don Choi
, Ki-Nam Shim
, Geun Am Song
, Oh Young Lee
, The Korean Society of Gastrointestinal Endoscopy Task Force on Clinical Practice Guidelines
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Clin Endosc 2024;57(2):141-157. Published online March 14, 2024
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DOI: https://doi.org/10.5946/ce.2024.002
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Abstract
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- Antithrombotic agents, including antiplatelet agents and anticoagulants, are widely used in Korea because of the increasing incidence of cardiocerebrovascular disease and the aging population. The management of patients using antithrombotic agents during endoscopic procedures is an important clinical challenge. The clinical practice guidelines for this issue, developed by the Korean Society of Gastrointestinal Endoscopy, were published in 2020. However, new evidence on the use of dual antiplatelet therapy and direct anticoagulant management has emerged, and revised guidelines have been issued in the United States and Europe. Accordingly, the previous guidelines were revised. Cardiologists were part of the group that developed the guideline, and the recommendations went through a consensus-reaching process among international experts. This guideline presents 14 recommendations made based on the Grading of Recommendations, Assessment, Development, and Evaluation methodology and was reviewed by multidisciplinary experts. These guidelines provide useful information that can assist endoscopists in the management of patients receiving antithrombotic agents who require diagnostic and elective therapeutic endoscopy. It will be revised as necessary to cover changes in technology, evidence, or other aspects of clinical practice.
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Mattia Bozzetti, Gennaro Pascale, Ilaria Marcomini, Alessio Lo Cascio, Fabio Grilli, Caterina Sclapari, Grazia Multari, Nicoletta Orgiana, Mirko Gaggiotti, Giorgio Iori, Luciana Nicola Giordano, Stefano Mancin, Fabio Petrelli, Giovanni Cangelosi, Loris Ri
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Liqi Sun, Jiang Liu
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Chung Hyun Tae, Ki-Nam Shim
Clinical Endoscopy.2025; 58(1): 80. CrossRef - Response
Tae-Geun Gweon, Hyun Gun Kim
Gastrointestinal Endoscopy.2025; 101(4): 925. CrossRef - Medical disputes involving lower gastrointestinal endoscopies: cases from the Korean Medical Dispute Mediation and Arbitration Agency
Eun Hye Oh, Jeong Eun Shin, Jun Yong Bae, Yoon Suk Lee, Yehyun Park, Yong Hwan Kwon, Chang Nyol Paik, Jun Kyu Lee, Tae Hee Lee
The Korean Journal of Internal Medicine.2025; 40(3): 404. CrossRef - Contemporary approaches in the peri-endoscopic management of antithrombotic agents: current paradigms, challenges, and prognostications
Jiaxuan Zuo, Wei Jiang, Lumei Wang, Kaiqi Yang, Peng Li, Shutian Zhang, Rui Cheng
Therapeutic Advances in Gastroenterology.2025;[Epub] CrossRef - Prediction of immediate bleeding after cold snare polypectomy: A prospective observational study
Shin Ju Oh, Yunho Jung, Young Hwangbo, Young Sin Cho, Il Kwun Chung, Chang Kyun Lee
Medicine.2024; 103(36): e39597. CrossRef
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Commentary
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Mucosal Incision-Assisted Endoscopic Biopsy as an Alternative to Endoscopic Ultrasound-Guided Fine-Needle Aspiration/Biopsy for Gastric Subepithelial Tumor
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Cheol Woong Choi
, Joo Ha Hwang
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Clin Endosc 2020;53(5):505-507. Published online September 29, 2020
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DOI: https://doi.org/10.5946/ce.2020.187
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R. Gayathri, C. S. Suchand Sandeep, C. Vijayan, V. M. Murukeshan
Biosensors.2023; 13(12): 1003. CrossRef - Laparoscopic transgastric enucleation of a giant leiomyoma near the esophagogastric junction
Jin Lee, Woo Yong Lee
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Yu-Ning Lin, Ming-Yan Chen, Chun-Yi Tsai, Wen-Chi Chou, Jun-Te Hsu, Chun-Nan Yeh, Ta-Sen Yeh, Keng-Hao Liu
Journal of Personalized Medicine.2022; 12(2): 297. CrossRef - Natural History of Asymptomatic Esophageal Subepithelial Tumors of 30 mm or Less in Size
Seokin Kang, Do Hoon Kim, Yuri Kim, Dongsub Jeon, Hee Kyong Na, Jeong Hoon Lee, Ji Yong Ahn, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
Journal of Korean Medical Science.2022;[Epub] CrossRef
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Focused Review Series: Recent Update of Endoscopic Ultrasonography in Gastrointestinal Subepithelial Tumors
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Current Status of Endoscopic Ultrasonography in Gastrointestinal Subepithelial Tumors
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Sang Gyun Kim
, Ji Hyun Song
, Joo Ha Hwang
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Clin Endosc 2019;52(4):301-305. Published online July 9, 2019
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DOI: https://doi.org/10.5946/ce.2019.024
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Abstract
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- Gastrointestinal subepithelial tumors (GSTs) are usually detected incidentally on endoscopic or radiologic examinations. In conventional endoscopy, a GST usually presents as a protuberant lesion with an intact mucosal surface. As the lesion is located beneath the mucosal layer of the gastrointestinal tract, conventional biopsy typically does not reveal the pathologic diagnosis. First, a GST should be differentiated from an extrinsic compression through the positional change of the patient during conventional endoscopic examination. In cases of GSTs originating from the gastrointestinal wall, endoscopic ultrasonography (EUS) can be beneficial for narrowing the differential diagnosis through delineation of echo findings and by determining the layer of origin. EUS findings can also help determine the management strategies for GSTs by making a differential diagnosis according to malignant potential.
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- Endoscopic Resection of Upper Gastrointestinal Subepithelial Tumours: Our Clinical Experience and Results
Mehmet Zeki Buldanlı, Oktay Yener
Prague Medical Report.2022; 123(1): 20. CrossRef - Gastric subepithelial tumor: long-term natural history and risk factors for progression
Bokyung Kim, Seungkyung Kang, Eunwoo Lee, Jinju Choi, Hyunsoo Chung, Soo-Jeong Cho, Sang Gyun Kim
Surgical Endoscopy.2022; 36(7): 5232. CrossRef - Traumatic neuroma of remnant cystic duct mimicking duodenal subepithelial tumor: A case report
Dong-Hwan Kim, Ji-Ho Park, Jin-Kyu Cho, Jung-Wook Yang, Tae-Han Kim, Sang-Ho Jeong, Young-Hye Kim, Young- Joon Lee, Soon-Chan Hong, Eun-Jung Jung, Young-Tae Ju, Chi-Young Jeong, Ju-Yeon Kim
World Journal of Clinical Cases.2020; 8(17): 3821. CrossRef
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Special Issue Articles of IDEN 2013
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Confocal Microscopy in the Esophagus and Stomach
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Adam Templeton, Joo Ha Hwang
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Clin Endosc 2013;46(5):445-449. Published online September 30, 2013
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DOI: https://doi.org/10.5946/ce.2013.46.5.445
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Abstract
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Probe-based confocal microscopy (pCLE) is actively being investigated for applications in the esophagus and stomach. The use of pCLE allows real-time in vivo microscopy to evaluate the microarchitecture of the mucosal epithelium. pCLE appears to be particularly useful in identifying mucosal dysplasia and early malignancies that cannot be clearly distinguished using high-definition white light endoscopy, chromoendoscopy, or magnification endoscopy. In addition, the ability to detect dysplastic tissue in real-time may shift the current screening practice from random biopsy to targeted biopsy of esophageal and gastric cancers and their precursor lesions. We will review the use of pCLE for detection and surveillance of upper gastrointestinal early luminal malignancy.
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Reut Friedman, Dvir Yelin
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Marek Kollar, Jana Krajciova, Lucia Prefertusova, Eva Sticova, Jana Maluskova, Zuzana Vackova, Jan Martinek
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Mu-Ni Hu, Shu-Hui Hu, Xing-Wei Zhang, Shu-Min Xiong, Huan Deng
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Shria Kumar, Jessica M Long, Gregory G Ginsberg, Bryson W Katona
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Robert J. Huang, Alyssa Y. Choi, Camtu D. Truong, Matthew M. Yeh, Joo Ha Hwang
Gut and Liver.2019; 13(6): 596. CrossRef - Probe-based confocal laser endomicroscopy (pCLE): a preclinical investigation of the male genital tract
Matthias Trottmann, Ronald Sroka, Herbert Stepp, Bernhard Liedl, Armin J. Becker, Christian G. Stief, Sabine Kölle
Lasers in Medical Science.2016; 31(1): 57. CrossRef - How to manage gastric polyps
Gandhi Lanke, Atin Agarwal, Jeffrey H. Lee
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Daniel Ruiz-Romero, Félix Ignacio Téllez-Ávila, Rafael Barreto-Zúñiga, Luis Eduardo Zamora-Nava.
Endoscopia.2015; 27(3): 135. CrossRef - Effect of Training in Upper Endoscopic Biopsy
Chang Seok Bang, Gwang Ho Baik, Jong Hyeok Kim, Jin Bong Kim, Ki Tae Suk, Jai Hoon Yoon, Yeon Soo Kim, Dong Joon Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2015; 15(1): 33. CrossRef - Real-time in-vivo imaging of pulmonary capillary perfusion using probe-based confocal laser scanning endomicroscopy in pigs
Sybille Gruber, Isabella Spielauer, Stefan Böhme, David Baron, Klaus Markstaller, Roman Ullrich, Klaus Ulrich Klein
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Kwang Hyun Ko, Na Young Han, Chang Il Kwon, Hoo Keun Lee, Jong Min Park, Eun Hee Kim, Ki Baik Hahm
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Endoscopic Ultrasound-Fine Needle Aspiration versus Core Biopsy for the Diagnosis of Subepithelial Tumors
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Kevin Webb, Joo Ha Hwang
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Clin Endosc 2013;46(5):441-444. Published online September 30, 2013
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DOI: https://doi.org/10.5946/ce.2013.46.5.441
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Abstract
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Subepithelial lesions are frequently encountered and remain a diagnostic challenge. Imaging of subepithelial lesions using endoscopic ultrasound (EUS) can be helpful in narrowing the differential diagnosis of the lesion; however, definitive diagnosis typically requires tissue. Many methods for acquiring tissue exist including EUS-guided fine needle aspiration, Trucut biopsy, and fine needle biopsy. Obtaining adequate tissue is important for cytologic and histologic exams including immunohistochemical stains, thus a great deal of effort has been made to increase tissue acquisition in order to improve diagnostic yield in subepithelial lesions.
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