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7 "Jun-Hyung Cho"
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Dedicated Cold Snare vs. Traditional Snare for Polypectomy of Diminutive and Small Lesions in a Porcine Model: A Research Group for Endoscopic Instruments and Stents (REIS) Study
Han Hee Lee, Bo-In Lee, Jung-Wook Kim, Hyun Lim, Si Hyung Lee, Jun-Hyung Cho, Yunho Jung, Kyoung Oh Kim, Chan Gyoo Kim, Kee Myung Lee, Jong-Jae Park, Myung-Gyu Choi, Hoon Jai Chun, Ho Gak Kim
Clin Endosc 2021;54(3):390-396.   Published online September 10, 2020
AbstractAbstract PDFSupplementary MaterialPubReaderePub
/Aims: The aim of this in vivo animal study was to evaluate the effectiveness and safety of dedicated cold snare (DCS) compared with those of traditional snare (TS) for cold snare polypectomy (CSP).
A total of 36 diminutive (5 mm) and 36 small (9 mm) pseudolesions were made by electrocoagulation in the colons of mini-pigs.
For the diminutive lesions, there were no significant differences in technical success rate, procedure time, or complete resection rate between the DCS and TS groups; the rate of uneven resection margin in the DCS group was significantly lower than that of the TS group. For small lesions, technical success rate and complete resection rate were significantly higher in the DCS group than in the TS group (100% [18/18] vs. 55.6% [10/18], p=0.003; 94.4% [17/18] vs. 40% [4/10], p=0.006). In addition, the procedure duration was significantly shorter, and the rate of uneven resection margin was significantly lower in the DCS group (28.5 sec vs. 66.0 sec, p=0.006; 11.1% [2/18] vs. 100% [10/10], p<0.001). Two cases of perforation occurred in the DCS group. Multivariate analysis revealed that DCS use was independently associated with complete resection.
DCS is superior to TS in terms of technical success, complete resection, and reducing the duration of the procedure for CSP of small polyps.


Citations to this article as recorded by  
  • Comparison of complete resection rates in cold snare polypectomy using two different wire diameter snares: A randomized controlled study
    Toshiki Horii, Sho Suzuki, Akihiro Sugita, Misa Yamauchi, Hisatomo Ikehara, Chika Kusano, Takuji Gotoda
    Journal of Gastroenterology and Hepatology.2023; 38(5): 752.     CrossRef
  • Comparison of the clinical efficacy of cold snare polypectomy using a thin-wire snare and thick-wire snare for small colorectal polyps
    Hong Jin Yoon, Yunho Jung, Young Sin Cho, Il-Kwun Chung
    International Journal of Gastrointestinal Intervention.2023; 12(4): 183.     CrossRef
  • Big Issues on Small Polyps: An Ideal Device, But Is It for an Ideal Indication?
    Yoji Takeuchi
    Clinical Endoscopy.2021; 54(3): 297.     CrossRef
  • Cold versus hot polypectomy/endoscopic mucosal resection–A review of current evidence
    Raquel Ortigão, Jochen Weigt, Ahmed Afifi, Diogo Libânio
    United European Gastroenterology Journal.2021; 9(8): 938.     CrossRef
  • 8,546 View
  • 223 Download
  • 4 Web of Science
  • 4 Crossref
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Efficacy of the Over-the-Scope Clip System for Treatment of Gastrointestinal Fistulas, Leaks, and Perforations: A Korean Multi-Center Study
Hang Lak Lee, Joo Young Cho, Jun-Hyung Cho, Jong Jae Park, Chan Gyoo Kim, Seong Hwan Kim, Joung-Ho Han
Clin Endosc 2018;51(1):61-65.   Published online August 29, 2017
AbstractAbstract PDFPubReaderePub
/Aims: Currently, a new over-the-scope clip (OTSC) system has been introduced. This system has been used for gastrointestinal perforations and fistulas in other countries. The aim of our study is to examine the therapeutic success rate of endoscopic treatment using the OTSC system in Korea.
This was a multicenter prospective study. A total of seven endoscopists at seven centers performed this procedure.
A total of 19 patients were included, with gastrointestinal leakages from anastomosis sites, fistulas, or esophageal perforations due to Boerhaave’s syndrome. Among these, there were three gastrojejunostomy sites, three esophagojejunostomy sites, four esophagogastrostomy sites, one esophagocolonostomy site, one jejuno-jejunal site, two endoscopic full thickness resection site closures, one Boerhaave’s syndrome, two esophago-bronchial fistulas, one gastrocolonic fistula, and one colonopseudocyst fistula. The size of the leakage ranged from 5 to 30 mm. The median procedure time was 16 min. All cases were technically successful. Complete closure of the leak was achieved in 14 of 19 patients using OTSC alone.
The OTSC system is a safe and effective method for the management of gastrointestinal leakage, especially in cases of anastomotic leakage after surgery.


Citations to this article as recorded by  
  • Problematic issues of diagnosis and treatment of Boerhaave’s syndrome
    V.S. Zhukovskiy, I.R. Trutyak, Ya.M. Pidhirnyi, Zh.V. Filip, M.V. Pankiv, V.S. Kozopas
    EMERGENCY MEDICINE.2024; 20(4): 226.     CrossRef
  • Bariatric surgery and reproduction-implications for gynecology and obstetrics
    Isaac A. Babarinsa, Mohammed Bashir, Husham AbdelRahman Ahmed, Badreldeen Ahmed, Justin C. Konje
    Best Practice & Research Clinical Obstetrics & Gynaecology.2023; 90: 102382.     CrossRef
  • Current status in endoscopic management of upper gastrointestinal perforations, leaks and fistulas
    Shannon Melissa Chan, Kitty Kit Ying Auyeung, Siu Fung Lam, Philip Wai Yan Chiu, Anthony Yuen Bun Teoh
    Digestive Endoscopy.2022; 34(1): 43.     CrossRef
  • Endoscopic vacuum therapy (EVT) for acute esophageal perforation: Could it replace surgery?
    Petros Stathopoulos, Malte Zumblick, Sabine Wächter, Leif Schiffmann, Thomas M. Gress, Detlef Bartsch, Guido Seitz, Ulrike W. Denzer
    Endoscopy International Open.2022; 10(05): E686.     CrossRef
  • Acquired Benign Tracheoesophageal Fistula
    Hasnain S. Bawaadam, Matthew Russell, Yaron B. Gesthalter
    Journal of Bronchology & Interventional Pulmonology.2022; 29(3): e38.     CrossRef
  • Exclusión pilórica con dispositivo Ovesco (over-thescope) en caso de fístula yeyunal en obstrucción duodenal de etiología maligna
    Raul Eduardo Pinilla Morales, Helena Facundo Navia, Elio Fabio Sánchez Cortés, Ivette C. Jiménez Lafourie, Álvaro Eduardo Sánchez Hernández, Luis Carlos Llorente Portillo
    Revista colombiana de Gastroenterología.2022; 37(3): 320.     CrossRef
  • Endoscopic management of leaks and fistulas after bariatric surgery: a systematic review and meta-analysis
    Pawel Rogalski, Agnieszka Swidnicka-Siergiejko, Justyna Wasielica-Berger, Damian Zienkiewicz, Barbara Wieckowska, Eugeniusz Wroblewski, Andrzej Baniukiewicz, Magdalena Rogalska-Plonska, Grzegorz Siergiejko, Andrzej Dabrowski, Jaroslaw Daniluk
    Surgical Endoscopy.2021; 35(3): 1067.     CrossRef
  • Endoscopic management of gastro‐bronchial fistula following two‐stage esophagectomy using over‐the‐scope‐clip (OTSC): Case series
    Chih Y. Tan, Htet A. Kyaw, Neda Farhangmehr, Cheuk‐Bong Tang, Naga V. Jayanthi
    Advances in Digestive Medicine.2021; 8(2): 84.     CrossRef
  • Over-the-Scope Clip Closure of Persistent Gastrocutaneous Fistula After Percutaneous Endoscopic Gastrostomy Tube Removal: A Report of Two Cases
    Shigenori Masaki, Keishi Yamada
    Cureus.2021;[Epub]     CrossRef
  • Over‐the‐scope clip: a novel approach to the management of a colorectal anastomotic leak
    Stephanie G. Jordan, Gregory J. Nolan
    ANZ Journal of Surgery.2021; 91(11): 2534.     CrossRef
  • Conservative treatment of patients with small bowel fistula
    A.V. Vodyasov, D.M. Kopaliani, P.A. Yartsev, O.Kh. Kaloeva
    Khirurgiya. Zhurnal im. N.I. Pirogova.2021; (4): 78.     CrossRef
  • An Approach to Accelerate Healing and Shorten the Hospital Stay of Patients With Anastomotic Leakage After Esophagectomy: An Explorative Study of Systematic Endoscopic Intervention
    LeQi Zhong, JiuDi Zhong, ZiHui Tan, YiTong Wei, XiaoDong Su, ZheSheng Wen, TieHua Rong, Yi Hu, KongJia Luo
    Frontiers in Oncology.2021;[Epub]     CrossRef
  • AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review
    Jeffrey H. Lee, Prashant Kedia, Stavros N. Stavropoulos, David Carr-Locke
    Clinical Gastroenterology and Hepatology.2021; 19(11): 2252.     CrossRef
  • Editors' Choice of Noteworthy Clinical Endoscopy Publications in the First Decade
    Gwang Ha Kim, Kwang An Kwon, Do Hyun Park, Jimin Han
    Clinical Endoscopy.2021; 54(5): 633.     CrossRef
  • Diagnostic challenge and surgical management of Boerhaave’s syndrome: a case series 
    Jiayue Wang, Degang Wang, Jianjiao Chen
    Journal of Medical Case Reports.2021;[Epub]     CrossRef
  • Over-the-scope clip management of non-acute, full-thickness gastrointestinal defects
    David J. Morrell, Joshua S. Winder, Ansh Johri, Salvatore Docimo, Ryan M. Juza, Samantha R. Witte, Vamsi V. Alli, Eric M. Pauli
    Surgical Endoscopy.2020; 34(6): 2690.     CrossRef
  • Use of the Over the Scope Clip to Close Perforations and Fistulas
    Panida Piyachaturawat, Parit Mekaroonkamol, Rungsun Rerknimitr
    Gastrointestinal Endoscopy Clinics of North America.2020; 30(1): 25.     CrossRef
  • Therapie der Ösophagusleckagen
    Jutta Weber-Eibel
    Journal für Gastroenterologische und Hepatologische Erkrankungen.2020; 18(1): 8.     CrossRef
  • Successful Closure of a Benign Refractory Tracheoesophageal Fistula Using an Over-the-Scope Clip after Failed Esophageal Stent Placement and Surgical Management
    Nonthalee Pausawasdi, Chotirot Angkurawaranon, Tanyaporn Chantarojanasiri, Arunchai Chang, Wanchai Wongkornrat, Somchai Leelakusolvong, Asada Methasate
    Clinical Endoscopy.2020; 53(3): 361.     CrossRef
  • Clinical efficacy of the over-the-scope clip device: A systematic review
    Nicholas Bartell, Krystle Bittner, Vivek Kaul, Truptesh H Kothari, Shivangi Kothari
    World Journal of Gastroenterology.2020; 26(24): 3495.     CrossRef
  • Endoscopic devices and techniques for the management of bariatric surgical adverse events (with videos)
    Allison R. Schulman, Rabindra R. Watson, Barham K. Abu Dayyeh, Manoop S. Bhutani, Vinay Chandrasekhara, Pichamol Jirapinyo, Kumar Krishnan, Nikhil A. Kumta, Joshua Melson, Rahul Pannala, Mansour A. Parsi, Guru Trikudanathan, Arvind J. Trindade, John T. Ma
    Gastrointestinal Endoscopy.2020; 92(3): 492.     CrossRef
  • Gastrointestinal tract injuries after thermal ablative therapies for hepatocellular carcinoma: A case report and review of the literature
    Teresa Marzia Rogger, Andrea Michielan, Sandro Sferrazza, Cecilia Pravadelli, Luisa Moser, Flora Agugiaro, Giovanni Vettori, Sonia Seligmann, Elettra Merola, Marcello Maida, Francesco Antonio Ciarleglio, Alberto Brolese, Giovanni de Pretis
    World Journal of Gastroenterology.2020; 26(35): 5375.     CrossRef
  • Over‐the‐scope clip system: A review of 1517 cases over 9 years
    Hideki Kobara, Hirohito Mori, Noriko Nishiyama, Shintaro Fujihara, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
    Journal of Gastroenterology and Hepatology.2019; 34(1): 22.     CrossRef
  • Recent advancements in the minimally invasive management of esophageal perforation, leaks, and fistulae
    Shirin Siddiqi, Dean P. Schraufnagel, Hafiz Umair Siddiqui, Michael J. Javorski, Adam Mace, Abdulrhman S. Elnaggar, Haytham Elgharably, Patrick R. Vargo, Robert Steffen, Saad M. Hasan, Siva Raja
    Expert Review of Medical Devices.2019; 16(3): 197.     CrossRef
  • Diagnosis and endoscopic treatment of esophageal leakage: a systematic review
    Bram D. Vermeulen, Peter D. Siersema
    Techniques in Gastrointestinal Endoscopy.2019; 21(2): 58.     CrossRef
  • Management of esophagojejunal anastomosis leakage after total gastrectomy
    Pablo Priego, Pietro Giordano, Marta Cuadrado, Araceli Ballestero, Julio Galindo, Eduardo Lobo
    European Surgery.2018; 50(6): 262.     CrossRef
  • Endoluminal Therapies for Esophageal Perforations and Leaks
    Jeffrey R. Watkins, Alexander S. Farivar
    Thoracic Surgery Clinics.2018; 28(4): 541.     CrossRef
  • Esophageal leaks: I thought that glue was not effective
    Ignacio Fernández-Urién, Juan Vila
    Endoscopy International Open.2018; 06(09): E1100.     CrossRef
  • 7,695 View
  • 326 Download
  • 26 Web of Science
  • 28 Crossref
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Focused Review Series: Image Enhanced Endoscopy
Advanced Imaging Technology Other than Narrow Band Imaging
Jun-Hyung Cho
Clin Endosc 2015;48(6):503-510.   Published online November 30, 2015
AbstractAbstract PDFPubReaderePub
To improve the detection rate of gastrointestinal tumors, image-enhanced endoscopy has been widely used during screening and surveillance endoscopy in Korea. In addition to narrow band imaging (NBI) with/without magnification, various types of electronic chromoendoscopies have been used, including autofluorescence imaging, I-scan, and flexible spectral imaging color enhancement. These technologies enable the accurate characterization of tumors because they enable visualization of microvascular and microsurface patterns. The present review focuses on understanding the principle and clinical applications of advanced imaging technologies other than NBI.


Citations to this article as recorded by  
  • Comparison of narrow-band imaging with autofluorescence imaging for endoscopic detection of squamous cell carcinoma of the tonsil
    J. Syba, K. Trnkova, L. Dostalova, M. Votava, E. Lukesova, S. Novak, M. Kana, M. Tesarova, M. Zabrodsky, J. Plzak, P. Lukes
    European Archives of Oto-Rhino-Laryngology.2023; 280(11): 5073.     CrossRef
  • A prospective study for evaluating the effect of gastric targeted biopsy sampling with I‐scan optical enhancement on the diagnostic yield of CLOtest for Helicobacter pylori infection
    Hosam Mohamed Dawod
    Health Science Reports.2022;[Epub]     CrossRef
  • Diagnostic Value of Endoscopic Narrow-Band Imaging Technique in Early Gastric Cancer and Precancerous Lesions
    Xianxin Huang, Rong Chen, Liang Zhao, Danilo Pelusi
    Scanning.2022; 2022: 1.     CrossRef
  • Endoscopy Lifetime Systems Architecture: Scoping Out the Past to Diagnose the Future Technology
    Craig M. Browning, Robert Cloutier, Thomas C. Rich, Silas J. Leavesley
    Systems.2022; 10(5): 189.     CrossRef
  • Biomedical Photonics for Intraoperative Diagnostics: Review of Capabilities and Clinical Applications
    E. A. Shirshin, B. P. Yakimov, G. S. Budylin, N. V. Zlobina, D. A. Davydov, A. G. Armaganov, V. V. Fadeev, N. N Sysoev, A. A. Kamalov
    Moscow University Physics Bulletin.2022; 77(6): 777.     CrossRef
  • Optimized diagnosis of Helicobacter pylori and tailored eradication therapy for preventing gastric cancer: a proposal for SHAKE strategy
    Jun-Hyung Cho, So-Young Jin
    Expert Review of Gastroenterology & Hepatology.2020; 14(7): 553.     CrossRef
  • Clinical applicability of gastroscopy with narrow-band imaging for the diagnosis of Helicobacter pylori gastritis, precancerous gastric lesion, and neoplasia
    Jun-Hyung Cho, Seong Ran Jeon, So-Young Jin
    World Journal of Clinical Cases.2020; 8(14): 2902.     CrossRef
  • Colonoscopy technologies for diagnostics and drug delivery
    Rajib Ahmed, Krieshshanthan Santhirakumar, Haider Butt, Ali K. Yetisen
    MEDICAL DEVICES & SENSORS.2019;[Epub]     CrossRef
  • A guide to multimodal endoscopy imaging for gastrointestinal malignancy — an early indicator
    Arthur Hoffman, Henrik Manner, Johannes W. Rey, Ralf Kiesslich
    Nature Reviews Gastroenterology & Hepatology.2017; 14(7): 421.     CrossRef
  • Linked color imaging application for improving the endoscopic diagnosis accuracy: a pilot study
    Xiaotian Sun, Tenghui Dong, Yiliang Bi, Min Min, Wei Shen, Yang Xu, Yan Liu
    Scientific Reports.2016;[Epub]     CrossRef
  • Narrow band imaging versus autofluorescence imaging for head and neck squamous cell carcinoma detection: a prospective study
    X-G Ni, Q-Q Zhang, G-Q Wang
    The Journal of Laryngology & Otology.2016; 130(11): 1001.     CrossRef
  • 13,095 View
  • 188 Download
  • 12 Web of Science
  • 11 Crossref
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Case Report
Endoscopic Treatment of Various Gastrointestinal Tract Defects with an Over-the-Scope Clip: Case Series from a Tertiary Referral Hospital
Woong Cheul Lee, Weon Jin Ko, Jun-Hyung Cho, Tae Hee Lee, Seong Ran Jeon, Hyun Gun Kim, Joo Young Cho
Clin Endosc 2014;47(2):178-182.   Published online March 31, 2014
AbstractAbstract PDFPubReaderePub

Recently, increasingly invasive therapeutic endoscopic procedures and more complex gastrointestinal surgeries such as endoscopic mucosal resection, endoscopic submucosal dissection, and novel laparoscopic approaches have resulted in endoscopists being confronted more frequently with perforations, fistulas, and anastomotic leakages, for which nonsurgical closure is desired. In this article, we present our experiences with the use of over-the-scope clip (OTSC) for natural orifice transluminal endoscopic surgery (NOTES) closure, prevention of perforation, anastomotic leakages, and fistula closures. The OTSC is a valuable device for closing intestinal perforations and fistulas, for NOTES closure, and for the prevention of perforation after the excision of a tumor from the proper muscle layer. Furthermore, it seems to be quite safe to perform, even by endoscopists with little experience of the technique.


Citations to this article as recorded by  
  • Experimental Evaluation of the Optimal Suture Pattern With a Flexible Endoscopic Suturing System
    Peter Halvax, Michele Diana, Yoshihiro Nagao, Jacques Marescaux, Lee Swanström
    Surgical Innovation.2017; 24(3): 201.     CrossRef
  • Management of non-acute gastrointestinal defects using the over-the-scope clips (OTSCs): a retrospective single-institution experience
    Joshua S. Winder, Afif N. Kulaylat, Jane R. Schubart, Hassan M. Hal, Eric M. Pauli
    Surgical Endoscopy.2016; 30(6): 2251.     CrossRef
  • Early endoscopic closure of colocutaneous fistula adjacent to unmatured low colorectal anastomosis with the Over-The-Scope Clip (OTSC)
    Constantinos Avgoustou, K. Paraskeva
    Hellenic Journal of Surgery.2016; 88(3): 193.     CrossRef
  • Endoscopic Closure for Full-Thickness Gastrointestinal Defects: Available Applications and Emerging Innovations
    Nobuyoshi Takeshita, Khek Yu Ho
    Clinical Endoscopy.2016; 49(5): 438.     CrossRef
  • 6,196 View
  • 59 Download
  • 3 Web of Science
  • 4 Crossref
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Brief Report
White Esophageal Mucosa and Black Gastric Mucosa: Upper Gastrointestinal Injury Due to Hydrochloric Acid Ingestion
Woong Cheul Lee, Tae Hee Lee, Jun-Hyung Cho
Clin Endosc 2014;47(1):119-120.   Published online January 24, 2014


Citations to this article as recorded by  
  • Severe Intentional Corrosive (Nitric Acid) Acute Poisoning: A Case Report and Literature Review
    Alexandra Stoica, Cătălina Lionte, Mădălina Palaghia, Irina Gîrleanu, Victoriţa Şorodoc, Alexandr Ceasovschih, Oana Sîrbu, Raluca Haliga, Cristina Bologa, Ovidiu Petriş, Vlad Nuţu, Ana Trofin, Gheorghe Bălan, Andreea Catana, Adorata Coman, Mihai Constanti
    Journal of Personalized Medicine.2023; 13(6): 987.     CrossRef
  • 5,224 View
  • 54 Download
  • 2 Web of Science
  • 1 Crossref
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Evidence-Based Recommendations on Upper Gastrointestinal Tract Stenting: A Report from the Stent Study Group of the Korean Society of Gastrointestinal Endoscopy
Sam Ryong Jee, Joo Young Cho, Kyung Ho Kim, Sang Gyun Kim, Jun-Hyung Cho, The Stent Study Group of the Korean Society of Gastrointestinal Endoscopy
Clin Endosc 2013;46(4):342-354.   Published online July 31, 2013
AbstractAbstract PDFPubReaderePub

Endoscopic stents have evolved dramatically over the past 20 years. With the introduction of uncovered self-expanding metal stents in the early 1990s, they are primarily used to palliate symptoms of malignant obstruction in patients with inoperable gastrointestinal (GI) cancer. At present, stents have emerged as an effective, safe, and less invasive alternative for the treatment of malignant GI obstruction. Clinical decisions about stent placement should be made based on the exact understanding of the patient's condition. These recommendations based on a critical review of the available data and expert consensus are made for the purpose of providing endoscopists with information about stent placement. These can be helpful for management of patients with inoperable cancer or various nonmalignant conditions in the upper GI tract.


Citations to this article as recorded by  
  • Endoscopic Procedures for Upper Gastrointestinal Tract Lesions and a Brief Review of Literature
    Selim Doğan, Ekrem Çakar, Bünyamin Gürbulak, Şükrü Çolak, Hasan Bektaş, Cihad Tatar
    Istanbul Medical Journal.2022; 23(2): 154.     CrossRef
  • Endoscopic Treatment of a Twisted Small Bowel Obstruction after Laparoscopic Proximal Gastrectomy with Double Tract Reconstruction
    Ki Bum Park, Seong Woo Jeon
    The Korean Journal of Gastroenterology.2020; 75(5): 296.     CrossRef
  • Temporary self-expandable metallic stent placement in post-gastrectomy complications
    Hyun Jin Oh, Chul-Hyun Lim, Seung Bae Yoon, Han Hee Lee, Jin Su Kim, Yu Kyung Cho, Jae Myung Park, Myung-Gyu Choi
    Gastric Cancer.2019; 22(1): 231.     CrossRef
  • Peptic Ulcer-related Stenosis
    Cheol Woong Choi
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2019; 19(1): 10.     CrossRef
  • Clinical Feasibility and Safety of Endoscopic Self-Expandable Metal Stent Placement for Upper Gastrointestinal Pathologies
    Bünyamin Gürbulak, Esin Kabul Gürbulak, Hasan Bektaş, İsmail Ethem Akgün, Hızır Yakup Akyildiz, Özgür Segmen, Fevzi Celayir, Muharrem Battal, Kenan Büyükaşık
    International Surgery.2018; 103(11-12): 605.     CrossRef
  • Endoscopic management of complications of self-expandable metal stents for treatment of malignant esophageal stenosis and tracheoesophageal fistulas
    Renáta Bor, Anna Fábián, Anita Bálint, Klaudia Farkas, Mónika Szűcs, Ágnes Milassin, László Czakó, Mariann Rutka, Tamás Molnár, Zoltán Szepes
    Therapeutic Advances in Gastroenterology.2017; 10(8): 599.     CrossRef
  • Gastroduodenal Outlet Obstruction and Palliative Self-Expandable Metal Stenting: A Dual-Centre Experience
    Nik S. Ding, Sina Alexander, Michael P. Swan, Christopher Hair, Patrick Wilson, Emma Clarebrough, David Devonshire
    Journal of Oncology.2013; 2013: 1.     CrossRef
  • 7,987 View
  • 52 Download
  • 7 Crossref
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Original Article
Peroral Endoscopic Myotomy for Treatment of Achalasia: Initial Results of a Korean Study
Byung Hoo Lee, Kwang Yeun Shim, Su Jin Hong, Gene Hyun Bok, Jun-Hyung Cho, Tae Hee Lee, Joo Young Cho
Clin Endosc 2013;46(2):161-167.   Published online March 31, 2013
AbstractAbstract PDFPubReaderePub

Achalasia is a rare esophageal motility disorder. Recently, a novel endoscopic technique, peroral endoscopic myotomy (POEM), was introduced as an alternative treatment for achalasia. We report the results and short term outcomes of POEM for patients with achalasia.


POEM was performed in 13 patients with achalasia. The procedure consisted of creating a submucosal tunnel followed by endoscopic myotomy of circular muscle bundles. The mucosal entry was closed by conventional hemostatic clips. A validated clinical symptom score (Eckardt score) and high resolution manometry were used to evaluate the outcomes.


Both the clinical score of achalasia, as well as the resting lower esophageal sphincter (LES) pressure, were significantly reduced after POEM. Mean posttreatment Eckardt score was 0.4±0.7, compared to 6.4±1.9 prior to the treatment (p=0.001). The mean pretreatment and posttreatment LES pressure was 30.3 and 15.3 mm Hg, respectively (p=0.007). Following POEM, symptomatic relief from dysphagia without reflux symptoms was observed in all patients (13/13). No serious complications related to POEM were encountered.


Based upon our initial experience, the authors believe that POEM is a feasible, safe, and effective treatment and may possibly substitute established treatments of refractory achalasia.


Citations to this article as recorded by  
  • Achalasia: Current therapeutic options
    Sebastien Rolland, William Paterson, Robert Bechara
    Neurogastroenterology & Motility.2023;[Epub]     CrossRef
  • Long versus short peroral endoscopic myotomy for the treatment of achalasia: results of a non-inferiority randomised controlled trial
    Pietro Familiari, Federica Borrelli de Andreis, Rosario Landi, Francesca Mangiola, Ivo Boskoski, Andrea Tringali, Vincenzo Perri, Guido Costamagna
    Gut.2023; 72(8): 1442.     CrossRef
  • Efficacy and Safety of Peroral Endoscopic Myotomy (POEM) in Achalasia: An Updated Meta-analysis
    Afshin Khaiser, Muhammad Baig, David Forcione, Matthew Bechtold, Srinivas R. Puli
    Middle East Journal of Digestive Diseases.2023; 15(4): 235.     CrossRef
  • Type II achalasia is associated with a comparably favorable outcome following per oral endoscopic myotomy
    Yutaka Tomizawa, Nadim Mahmud, Kevin Dasher, Joseph R Triggs, Monica Saumoy, Gary W Falk, Gregory G Ginsberg
    Diseases of the Esophagus.2021;[Epub]     CrossRef
  • Miotomía endoscópica peroral para el tratamiento de acalasia y otros trastornos motores del esófago. Resultados a corto y mediano plazo en un centro de referencia en México
    O.V. Hernández-Mondragón, O.M. Solórzano-Pineda, M.A. González-Martínez, J.M. Blancas-Valencia, C. Caballero-Luengas
    Revista de Gastroenterología de México.2019; 84(1): 1.     CrossRef
  • Peroral endoscopic myotomy for the treatment of achalasia and other esophageal motor disorders: Short-term and medium-term results at a Mexican tertiary care center
    O.V. Hernández-Mondragón, O.M. Solórzano-Pineda, M.A. González-Martínez, J.M. Blancas-Valencia, C. Caballero-Luengas
    Revista de Gastroenterología de México (English Edition).2019; 84(1): 1.     CrossRef
  • Bridging the Gap between Advancements in the Evolution of Diagnosis and Treatment towards Better Outcomes in Achalasia
    Seng-Kee Chuah, Chee-Sang Lim, Chih-Ming Liang, Hung-I Lu, Keng-Liang Wu, Chi-Sin Changchien, Wei-Chen Tai
    BioMed Research International.2019; 2019: 1.     CrossRef
  • Preliminary study of 1940 nm thulium laser usage in peroral endoscopic myotomy for achalasia
    J Liu, Y Jiao, Y Niu, L Yu, M Ji, S Zhang
    Diseases of the Esophagus.2018;[Epub]     CrossRef
  • POEM in the Treatment of Esophageal Disorders
    Nasim Parsa, Mouen A. Khashab
    Current Treatment Options in Gastroenterology.2018; 16(1): 27.     CrossRef
  • Current Status of Peroral Endoscopic Myotomy
    Young Kwan Cho, Seong Hwan Kim
    Clinical Endoscopy.2018; 51(1): 13.     CrossRef
  • Safety and efficacy of POEM for treatment of achalasia: a systematic review of the literature
    Oscar M. Crespin, Louis W. C. Liu, Ambica Parmar, Timothy D. Jackson, Jemila Hamid, Eran Shlomovitz, Allan Okrainec
    Surgical Endoscopy.2017; 31(5): 2187.     CrossRef
  • Early adverse events of per-oral endoscopic myotomy
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    Gut and Liver.2017; 11(5): 642.     CrossRef
  • Peroral endoscopic myotomy for the treatment of esophageal achalasia: systematic review and pooled analysis
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  • Gastroesophageal reflux disease after peroral endoscopic myotomy: Analysis of clinical, procedural and functional factors, associated with gastroesophageal reflux disease and esophagitis
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    Medicine.2016; 95(10): e3001.     CrossRef
  • Prospective evaluation of CT esophagram findings after peroral endoscopic myotomy
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    Gut.2016; 65(6): 899.     CrossRef
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