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Recently, increasingly invasive therapeutic endoscopic procedures and more complex gastrointestinal surgeries such as endoscopic mucosal resection, endoscopic submucosal dissection, and novel laparoscopic approaches have resulted in endoscopists being confronted more frequently with perforations, fistulas, and anastomotic leakages, for which nonsurgical closure is desired. In this article, we present our experiences with the use of over-the-scope clip (OTSC) for natural orifice transluminal endoscopic surgery (NOTES) closure, prevention of perforation, anastomotic leakages, and fistula closures. The OTSC is a valuable device for closing intestinal perforations and fistulas, for NOTES closure, and for the prevention of perforation after the excision of a tumor from the proper muscle layer. Furthermore, it seems to be quite safe to perform, even by endoscopists with little experience of the technique.

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Endoscopic stents have evolved dramatically over the past 20 years. With the introduction of uncovered self-expanding metal stents in the early 1990s, they are primarily used to palliate symptoms of malignant obstruction in patients with inoperable gastrointestinal (GI) cancer. At present, stents have emerged as an effective, safe, and less invasive alternative for the treatment of malignant GI obstruction. Clinical decisions about stent placement should be made based on the exact understanding of the patient's condition. These recommendations based on a critical review of the available data and expert consensus are made for the purpose of providing endoscopists with information about stent placement. These can be helpful for management of patients with inoperable cancer or various nonmalignant conditions in the upper GI tract.

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  Journal of Neurogastroenterology and Motility.2015; 22(1): 14.     CrossRef
• Effect of Peroral Endoscopic Myotomy on Esoph ageal Motor Function
  Su Jin Hong
  Journal of Neurogastroenterology and Motility.2015; 22(1): 1.     CrossRef
• Achalasia: current treatment options
  Pietro Familiari, Santi Greco, Ance Volkanovska, Giovanni Gigante, Anna Cali, Ivo Boškoski, Guido Costamagna
  Expert Review of Gastroenterology & Hepatology.2015; 9(8): 1101.     CrossRef
• Systematic review and meta‐analysis: Efficacy and safety of POEM for achalasia
  Lavinia A Barbieri, Cesare Hassan, Riccardo Rosati, Uberto Fumagalli Romario, Loredana Correale, Alessandro Repici
  United European Gastroenterology Journal.2015; 3(4): 325.     CrossRef
• Per-oral endoscopic myotomy white paper summary
  Stavros N. Stavropoulos, David J. Desilets, Karl-Hermann Fuchs, Christopher J. Gostout, Gregory Haber, Haruhiro Inoue, Michael L. Kochman, Rani Modayil, Thomas Savides, Daniel J. Scott, Lee L. Swanstrom, Melina C. Vassiliou
  Surgical Endoscopy.2014; 28(7): 2005.     CrossRef
• Peroral endoscopic myotomy for achalasia
  A. J. Bredenoord, T. Rösch, P. Fockens
  Neurogastroenterology & Motility.2014; 26(1): 3.     CrossRef
• Peroral Endoscopic Myotomy: Establishing a New Program
  Nikhil A. Kumta, Shivani Mehta, Prashant Kedia, Kristen Weaver, Reem Z. Sharaiha, Norio Fukami, Hitomi Minami, Fernando Casas, Monica Gaidhane, Arnon Lambroza, Michel Kahaleh
  Clinical Endoscopy.2014; 47(5): 389.     CrossRef
• Introduction of the per-oral endoscopic myotomy technique to pediatric surgical practice
  Stephanie Chao, Michael Russo, Robert Wright, Homero Rivas, James Wall
  Journal of Pediatric Surgery Case Reports.2014; 2(6): 313.     CrossRef
• International Digestive Endoscopy Network 2014: Turnpike to the Future
  Eun Young Kim, Kwang An Kwon, Il Ju Choi, Ji Kon Ryu, Ki Baik Hahm
  Clinical Endoscopy.2014; 47(5): 371.     CrossRef
• Per-oral endoscopic myotomy white paper summary
  Stavros N. Stavropoulos, David J. Desilets, Karl-Hermann Fuchs, Christopher J. Gostout, Gregory Haber, Haruhiro Inoue, Michael L. Kochman, Rani Modayil, Thomas Savides, Daniel J. Scott, Lee L. Swanstrom, Melina C. Vassiliou
  Gastrointestinal Endoscopy.2014; 80(1): 1.     CrossRef
• Effectiveness of peroral endoscopic myotomy in the treatment of achalasia: A pilot trial in Chinese Han population with a minimum of one‐year follow‐up
  Ting Sheng Ling, Hui Min Guo, Tian Yang, Chun Yan Peng, Xiao Ping Zou, Rui Hua Shi
  Journal of Digestive Diseases.2014; 15(7): 352.     CrossRef
• Jackhammer Esophagus Treated by a Peroral Endoscopic Myotomy
  Weon Jin Ko, Byoung Moo Lee, Won Young Park, Jin Nyoung Kim, Jun-Hyung Cho, Tae Hee Lee, Su Jin Hong, Joo Young Cho
  The Korean Journal of Gastroenterology.2014; 64(6): 370.     CrossRef
• Effect of peroral endoscopic myotomy in achalasia patients with failure of prior pneumatic dilation: A prospective case–control study
  Tingsheng Ling, Huimin Guo, Xiaoping Zou
  Journal of Gastroenterology and Hepatology.2014; 29(8): 1609.     CrossRef
• Medical and Endoscopic Management of Achalasia
  Jae Pil Han, Su Jin Hong
  The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2014; 14(2): 82.     CrossRef
• EndoFLIP system for the intraoperative evaluation of peroral endoscopic myotomy
  Pietro Familiari, Giovanni Gigante, Michele Marchese, Ivo Boskoski, Vincenzo Bove, Andrea Tringali, Vincenzo Perri, Graziano Onder, Guido Costamagna
  United European Gastroenterology Journal.2014; 2(2): 77.     CrossRef
• Per Oral Endoscopic Myotomy (POEM): Review of Current Techniques and Outcomes (Including Postoperative Reflux)
  David Friedel, Rani Modayil, Stavros N. Stavropoulos
  Current Surgery Reports.2013; 1(4): 203.     CrossRef
• Peroral Endoscopic Myotomy for the Treatment of Achalasia: An Analysis
  Dennis Yang, Mihir S. Wagh
  Diagnostic and Therapeutic Endoscopy.2013; 2013: 1.     CrossRef
• Therapeutic flexible endoscopy replacing surgery: Part 3—Peroral esophageal myotomy
  Ezra N. Teitelbaum, Eric S. Hungness
  Techniques in Gastrointestinal Endoscopy.2013; 15(4): 211.     CrossRef
• Highlights of International Digestive Endoscopy Network 2013
  Kwang An Kwon, Il Ju Choi, Eun Young Kim, Seok Ho Dong, Ki Baik Hahm
  Clinical Endoscopy.2013; 46(5): 425.     CrossRef
• Perorale endoskopische Myotomie zur Therapie der Achalasie
  B.H.A. von Rahden, J. Filser, S. Reimer, H. Inoue, C.-T. Germer
  Der Chirurg.2013;[Epub]     CrossRef