Background /Aims: Small bowel malignancies often present a diagnostic challenge due to their relative rarity and nonspecific clinical symptoms. However, technical developments in endoscopic instruments, including video capsule endoscopy (VCE) and enteroscopy, have allowed for the visualization of the entire small bowel. This study aimed to investigate the clinicopathological features of small bowel malignant tumors diagnosed by VCE and double-balloon enteroscopy (DBE) in a single tertiary center.
Methods We retrospectively analyzed VCE and DBE findings from Korea University Guro Hospital from January 2010 through September 2018.
Results A total of 510 VCE and 126 DBE examinations were performed in 438 patients. Small bowel malignancies were diagnosed in 28 patients (15 males; mean age, 61.0 years; range, 42 to 81 years). Among them, 8 had lymphoma, 8 had primary adenocarcinoma, 7 had gastrointestinal stromal tumor (GIST) and 5 had metastatic cancer. Abdominal pain and obstructive symptoms were the most common findings in metastatic cancers (4/5, 80%). On the other hand, obscure gastrointestinal bleeding was the most common symptom of GIST (6/7, 85.7%) and adenocarcinoma (3/8, 37.5%).
Conclusions Approximately 6% of the patients who underwent either VCE or DBE were diagnosed with small bowel malignancy. These findings demonstrated the different clinical characteristics among small bowel malignancies and merit further study.
Citations
Citations to this article as recorded by
Balloon-assisted enteroscopy in the management of adult small-bowel intussusception: a comparative analysis of with and without double-balloon enteroscopy Won Shik Kim, Beom Jae Lee, Moon Kyung Joo, Seung Han Kim, Jong-Jae Park Surgical Endoscopy.2025;[Epub] CrossRef
Prognostic factors for liver metastasis in patients with small intestinal stromal tumor: A retrospective analysis of surveillance, epidemiology, and end results Luojie Liu, Rufa Zhang, Zhenguo Qiao, Ye Ye, Kaijian Xia, Yunfu Feng, Xiaodan Xu World Journal of Surgery.2024; 48(3): 598. CrossRef
Primitive Resectable Small Bowel Cancer Clinical–Pathological Analysis: A 10-Year Retrospective Study in a General Surgery Unit Cosmin Vasile Obleagă, Costin Teodor Streba, Cecil Sorin Mirea, Ionică Daniel Vîlcea, Dan Nicolae Florescu, Mihai Călin Ciorbagiu, Tudor Turcu, Mirela Marinela Florescu, Mircea Sebastian Șerbănescu, Alina-Maria Mehedințeanu, Cristin Constantin Vere Cancers.2024; 16(21): 3713. CrossRef
A practical approach for small bowel bleeding Sung Eun Kim, Hyun Jin Kim, Myeongseok Koh, Min Cheol Kim, Joon Sung Kim, Ji Hyung Nam, Young Kwan Cho, A Reum Choe Clinical Endoscopy.2023; 56(3): 283. CrossRef
Clinicopathological characteristics and prognostic factors of small bowel lymphomas: a retrospective single-center study Emanuel Dias, Renato Medas, Margarida Marques, Patrícia Andrade, Hélder Cardoso, Guilherme Macedo Porto Biomedical Journal.2023;[Epub] CrossRef
Small Bowel Capsule Endoscopy and Enteroscopy: A Shoulder-to-Shoulder Race Ana-Maria Singeap, Catalin Sfarti, Horia Minea, Stefan Chiriac, Tudor Cuciureanu, Robert Nastasa, Carol Stanciu, Anca Trifan Journal of Clinical Medicine.2023; 12(23): 7328. CrossRef
Symptoms Contributing to the Diagnosis of Small Bowel Tumors Kozo Tsuruta, Hidetoshi Takedatsu, Shinichiro Yoshioka, Masahiro Yoshikai, Kensuke Tomiyasu, Masaru Morita, Kotaro Kuwaki, Keiichi Mitsuyama, Takumi Kawaguchi Digestion.2023; 104(6): 430. CrossRef
Small bowel lymphoma: clinical update and challenges for the gastroenterologist Priya Oka, Reena Sidhu Current Opinion in Gastroenterology.2022; 38(3): 270. CrossRef
Indication, Location of the Lesion, Diagnostic Yield, and Therapeutic Yield of Double-Balloon Enteroscopy: Seventeen Years of Experience Sang Pyo Lee, Hyun Joo Jang, Sea Hyub Kae, Jae Gon Lee, Ji Hye Kwon Diagnostics.2022; 12(9): 2224. CrossRef
Minimally invasive surgery with adenocarcinoma of jejunum diagnosed pathologically before surgery: A case report Sung Chul Lee International Journal of Surgery Case Reports.2021; 79: 354. CrossRef
Predictors of Positive Video Capsule Endoscopy Findings for Chronic Unexplained Abdominal Pain: Single-Center Retrospective Study and Meta-Analysis Wonshik Kim, Beomjae Lee, Ahyoung Yoo, Seunghan Kim, Moonkyung Joo, Jong-Jae Park Diagnostics.2021; 11(11): 2123. CrossRef
Small Bowel Malignancies in Patients Undergoing Capsule Endoscopy for Iron Deficiency Anemia Su Hwan Kim, Ji Won Kim Diagnostics.2021; 12(1): 91. CrossRef
Melanocytic nevus is the benign proliferation of melanocytes. The most common location of melanocytic nevus is the skin of the extremities; however, there are few case reports of melanocytic nevus at the rectal mucosa. No prior case of malignant melanoma from melanocytic nevus at the rectal mucosa has been reported; therefore, it is unclear whether resection should be performed or close observation is sufficient. However, the potential malignant transformation of melanocytic nevus should be considered, including melanocytic nevus on the rectum. Melanocytic nevus of the skin can be removed by surgical excision; however, due to rare incidence on the mucosa of the gastrointestinal tract, the optimal treatment for rectal melanocytic nevus remains controversial. Here, we report the first case of melanocytic nevus on the rectal mucosa that was removed by endoscopic submucosal dissection. This case report provides useful information about the optimal management of rectal melanocytic nevus.