KSGE
Search
- Page Path
- HOME > Search
Brief Report
- Awareness of green endoscopy is low among healthcare professionals performing gastrointestinal endoscopy
- Tae Joo Jeon, Jae Myung Cha
- Clin Endosc 2024;57(6):836-838. Published online July 25, 2024
- DOI: https://doi.org/10.5946/ce.2024.004
- 2,728 View
- 96 Download
Original Article
- Factors Associated with Malignant Biliary Strictures in Patients with Atypical or Suspicious Cells on Brush Cytology
- Ji Young Park, Tae Joo Jeon
- Clin Endosc 2019;52(2):168-174. Published online January 9, 2019
- DOI: https://doi.org/10.5946/ce.2018.105
-
Abstract
PDF
PubReader
ePub - Background
/Aims: Pathological diagnosis of biliary strictures with atypical or suspicious cells on endoscopic retrograde brush cytology and indeterminate strictures on imaging is challenging. The aim of this study was to identify markers for malignant strictures in such cases.
Methods
We retrospectively analyzed data collected from 146 consecutive patients with indeterminate biliary strictures on imaging who underwent endoscopic retrograde brush cytology from 2007 to 2013. Factors associated with malignant strictures in patients with atypical or suspicious cells on brush cytology were identified.
Results
Among the 67 patients with a malignant disease (48 cholangiocarcinoma, 6 gallbladder cancer, 5 pancreatic cancer, 5 ampulla of Vater cancer, and 3 other types), 36 (53.7%) had atypical or suspicious cells on brush cytology. Among these, the factors that independently correlated with malignant strictures were stricture length (odds ratio [OR], 5.259; 95% confidence interval [CI], 1.802– 15.294) and elevated carbohydrate antigen 19-9 (CA19-9) (OR, 3.492; 95% CI, 1.242–9.815), carcinoembryonic antigen (CEA) (OR, 4.909; 95% CI, 1.694–14.224), alkaline phosphatase (ALP) (OR, 3.362; 95% CI, 1.207–9.361), and gamma-glutamyl transpeptidase (rGT) (OR, 4.318; 95% CI, 1.512–12.262).
Conclusions
Elevated levels of CA19-9, CEA, ALP, and rGT and stricture length are associated with malignant strictures in patients with indeterminate biliary strictures on imaging and atypical or suspicious cells on brush cytology. -
Citations
Citations to this article as recorded by
- High Diagnostic Yield of Endoscopic Retrograde Cholangiopancreatography Brush Cytology for Indeterminate Strictures
Abdulsemed M Nur, Misbah Salim, Scott Boerner, Suqing Li, Cindy C Y Law, Leanne Edwards, Kaitlin Ryan, Paul D James
Journal of the Canadian Association of Gastroenterology.2022; 5(5): 234. CrossRef - Digital Image Analysis has an Additive Beneficial Role to Conventional Cytology in Diagnosing the Nature of Biliary Ducts Stricture
Ahmed Helmy, Heba Mohamed Saad Eldien, Gehan Sayed Seifeldein, Ahmed Mohammed Abu-Elfatth, Adnan Ahmed Mohammed
Journal of Clinical and Experimental Hepatology.2021; 11(2): 209. CrossRef - Predicting Malignancy of Biliary Stricture with a Nomogram in Patients with a Non-Malignant Endoscopic Tissue Diagnosis: A Retrospective Study
Yizhen Zhang, Qingwei Jiang, Qiang Wang, Yunlu Feng, Dongsheng Wu, Tao Guo, Shengyu Zhang, Xi Chen, Yingyun Yang, Wen Shi, Xi Wu, Aiming Yang
Cancer Management and Research.2021; Volume 13: 7735. CrossRef - Tips and tricks for the diagnosis and management of biliary stenosis-state of the art review
Giovanna Del Vecchio Blanco, Michelangela Mossa, Edoardo Troncone, Renato Argirò, Andrea Anderloni, Alessandro Repici, Omero Alessandro Paoluzi, Giovanni Monteleone
World Journal of Gastrointestinal Endoscopy.2021; 13(10): 473. CrossRef - How Can We Differentiate Malignant Biliary Strictures from Clinically Indeterminate Biliary Strictures?
Eui Joo Kim, Jae Hee Cho
Clinical Endoscopy.2019; 52(2): 95. CrossRef
- High Diagnostic Yield of Endoscopic Retrograde Cholangiopancreatography Brush Cytology for Indeterminate Strictures
- 6,051 View
- 92 Download
- 5 Web of Science
- 5 Crossref
First
Prev
