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2 "Young Chul Choi"
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Original Article
Peroral Endoscopic Myotomy for Treating Achalasia in an Animal Model: A Feasibility Study
Byoung Wook Bang, Young Chul Choi, Hyung Gil Kim, Kye Sook Kwon, Yong Woon Shin, Don Haeng Lee, Joon Mee Kim
Clin Endosc 2013;46(1):54-58.   Published online January 31, 2013
DOI: https://doi.org/10.5946/ce.2013.46.1.54
AbstractAbstract PDFPubReaderePub
Background/Aims

Laparoscopic Heller myotomy with antireflux procedure is considered to be a standard treatment for achalasia. Recently, peroral endoscopic myotomy (POEM) was developed and performed on patients with achalasia. However, there is no report on POEM use in South Korea. The aim of this study was to evaluate the technical feasibility of POEM in a porcine model.

Methods

POEM was performed on two mini pigs. We performed upper endoscopy under general anesthesia. A submucosal tunnel was created and the circular muscle layer was incised using several knives. The mucosal entry was closed using resolution clips. We performed a follow-up endoscopy and sacrificed the pigs 2 weeks after the POEM. The myotomy site was evaluated grossly and histologically.

Results

POEM was successfully performed on the two mini pigs. No injuries to any abdominal or mediastinal structures occurred. Two weeks after the POEM, the esophageal mucosa healed without any endoscopic evidence of complications. Necropsy revealed that the circular muscle layer was completely lost and replaced with fibrotic tissue.

Conclusions

We found that POEM is a technically feasible method which can be performed on an animal model. However, to ensure safe use on patients with achalasia, further studies on technical methods and long-term follow-up examinations are required.

Citations

Citations to this article as recorded by  
  • Pilot prospective study on formal training in per-oral endoscopic myotomy (POEM) during advanced endoscopy fellowship
    Salmaan Jawaid, Peter V. Draganov, Hiroyuki Aihara, Mouen A. Khashab, Dennis Yang
    Endoscopy International Open.2021; 09(12): E1890.     CrossRef
  • Miotomía endoscópica peroral, experiencia in vivo : imprescindible para desarrollo de la técnica en humanos
    A. Peñaloza-Ramírez, J. Suárez-Correa, J. Báez-Blanco, C. Sabogal-Gómez, H. Kuan-Casas, C. Sánchez-Pignalosa, P. Aponte-Ordóñez
    Revista de Gastroenterología de México.2018; 83(2): 86.     CrossRef
  • In vivo experience with peroral endoscopic myotomy: An essential activity for developing the technique in humans
    A. Peñaloza-Ramírez, J. Suárez-Correa, J. Báez-Blanco, C. Sabogal-Gómez, H. Kuan-Casas, C. Sánchez-Pignalosa, P. Aponte-Ordóñez
    Revista de Gastroenterología de México (English Edition).2018; 83(2): 86.     CrossRef
  • Factors predicting the technical difficulty of peroral endoscopic myotomy for achalasia
    Xiaowei Tang, Yutang Ren, Zhengjie Wei, Jieqiong Zhou, Zhiliang Deng, Zhenyu Chen, Bo Jiang, Wei Gong
    Surgical Endoscopy.2016; 30(9): 3774.     CrossRef
  • Peroral endoscopic myotomy for treatment of achalasia in children and adolescents
    Chenjie Li, Yuyong Tan, Xuehong Wang, Deliang Liu
    Journal of Pediatric Surgery.2015; 50(1): 201.     CrossRef
  • The Ideal Experimental Training Session for Minimally Invasive Endoluminal Techniques
    Sakai P
    Gastroenterology & Hepatology: Open Access.2015;[Epub]     CrossRef
  • International Digestive Endoscopy Network 2014: Turnpike to the Future
    Eun Young Kim, Kwang An Kwon, Il Ju Choi, Ji Kon Ryu, Ki Baik Hahm
    Clinical Endoscopy.2014; 47(5): 371.     CrossRef
  • Training for peroral endoscopic myotomy
    Daniel von Renteln, Melina C. Vassiliou, Thomas Rösch
    Techniques in Gastrointestinal Endoscopy.2013; 15(3): 153.     CrossRef
  • Peroral Endoscopic Myotomy for the Treatment of Achalasia: An Analysis
    Dennis Yang, Mihir S. Wagh
    Diagnostic and Therapeutic Endoscopy.2013; 2013: 1.     CrossRef
  • Peroral Endoscopic Myotomy in a Porcine Model: A Step to Achalasia Patients
    Su Jin Hong
    Clinical Endoscopy.2013; 46(1): 1.     CrossRef
  • 6,284 View
  • 59 Download
  • 10 Crossref
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Case Report
Two Cases of Ileal Dieulafoy Lesion with Massive Hematochezia Treated by Single Balloon Enteroscopy
Young Chul Choi, Sang Hyun Park, Byoung Wook Bang, Kye Sook Kwon, Hyung Gil Kim, Yong Woon Shin
Clin Endosc 2012;45(4):440-443.   Published online November 30, 2012
DOI: https://doi.org/10.5946/ce.2012.45.4.440
AbstractAbstract PDFPubReaderePub

Ileal Dieulafoy lesion is an unusual vascular abnormality that can cause gastrointestinal bleeding. It can be associated with massive, life-threatening hemorrhage and requires urgent angiographic intervention or surgery. Ileal Dieulafoy lesion is hard to recognize due to inaccessibility and normal-appearing mucosa. With advances in endoscopy, aggressive diagnostic and therapeutic approaches including enteroscopy have recently been performed for small bowel bleeding. We report two cases of massive ileal Dieulafoy lesion bleeding diagnosed and treated successfully by single balloon enteroscopy with a review of the literature.

Citations

Citations to this article as recorded by  
  • A diagnostic dilemma: a case report of concomitant duodenal Dieulafoy lesion and gastric ulcer
    Lauren Wallace, Peter J Gallagher
    Journal of Surgical Case Reports.2024;[Epub]     CrossRef
  • Stitch in time saves nine
    Aisha Rummaan, Irene Lee, Deepa Rattehalli, Prajesh Kumar, Sauid Ishaq
    Frontline Gastroenterology.2023; 14(3): 265.     CrossRef
  • Ileal Dieulafoy Lesion: a rare case report
    Aleena Jain, Manjusha Karegar, Amita Joshi, Amey Rojekar
    Surgical and Experimental Pathology.2018;[Epub]     CrossRef
  • The Role of Emergency Endoscopy in Small Bowel Bleeding: A Review
    Enrique Pérez-Cuadrado-Robles, Enrique Pérez-Cuadrado-Martínez
    GE Portuguese Journal of Gastroenterology.2016; 23(2): 84.     CrossRef
  • An Unusual Cause of Torrential Lower Gastrointestinal Hemorrhage
    Terence C. Chua, Anthony J. Gill, Jaswinder S. Samra
    Gastroenterology.2015; 148(5): e10.     CrossRef
  • 7,959 View
  • 41 Download
  • 5 Crossref
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