Clinical Endoscopy

Focused Review Series: Image-Enhanced Endoscopy: Update on Clinical Practice

Clinical Efficacy of Endocytoscopy for Gastrointestinal Endoscopy: Masashi Misawa, Shin-ei Kudo, Yuki Takashina, Yoshika Akimoto, Yasuharu Maeda, Yuichi Mori, Toyoki Kudo, Kunihiko Wakamura, Hideyuki Miyachi, Fumio Ishida, Haruhiro Inoue; Clin Endosc 2021;54(4):455-463. Published online July 7, 2021; DOI: https://doi.org/10.5946/ce.2021.165

Abstract PDF Supplementary Material PubReader ePub

Endocytoscopy (EC) is a contact-type optical endoscope that allows in vivo cellular observation during gastrointestinal endoscopy and is now commercially available not only in Japan but also in Asian, European Union, and Middle Eastern countries. EC helps conduct a highly accurate pathological prediction without biopsy. Initially, EC was reported to be effective for esophageal diseases. Subsequently, its efficacy for stomach and colorectal diseases has been reported. In this narrative review, we searched for clinical studies that investigated the efficacy of EC. EC seems to accurately diagnose gastrointestinal diseases without biopsy. Most of the studies aimed to clarify the relationship between endocytoscopic findings of gastrointestinal neoplasia and pathological diagnosis. Some studies have investigated non-epithelial lesions or diseases, such as inflammatory bowel disease or infectious diseases. However, there are few high-level pieces of evidence, such as randomized trials; thus, further studies are needed.

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Advanced Endoscopic Imaging for Assessing Mucosal Healing and Histologic Remission in Inflammatory Bowel Diseases
Tommaso Pessarelli, Gian Eugenio Tontini, Helmut Neumann
Gastrointestinal Endoscopy Clinics of North America.2025; 35(1): 159. CrossRef
Automated Endoscopic Diagnosis in IBD
Yasuharu Maeda, Shin-ei Kudo, Takanori Kuroki, Marietta Iacucci
Gastrointestinal Endoscopy Clinics of North America.2025; 35(1): 213. CrossRef
Endocitoscopia de la muscular propia en acalasia de rápida evolución y recidiva de acalasia post-Heller
Hugo Uchima, Raquel Muñoz-González, Íngrid Marín, Noemí Caballero, Claudia Cepero, Ignacio Iborra, Juan Colán-Hernández, Edgar Castillo, Vicente Moreno
Gastroenterología y Hepatología.2024; 47(7): 761. CrossRef
Endocytoscopy of muscularis propria in rapidly evolving achalasia and recurrence of post-Heller achalasia
Hugo Uchima, Raquel Muñoz-González, Íngrid Marín, Noemí Caballero, Claudia Cepero, Ignacio Iborra, Juan Colán-Hernández, Edgar Castillo, Vicente Moreno
Gastroenterología y Hepatología (English Edition).2024; 47(7): 761. CrossRef
The diagnostic utility of endocytoscopy for the detection of gastric cancer: a systematic review and meta-analysis
Andrew CANAKIS, Shivanand BOMMAN, Benjamin TWERY, Nevin VARGHESE, Byung JI, Justin CANAKIS, Eric M. GOLDBERG
Minerva Gastroenterology.2024;[Epub] CrossRef
The diagnostic utility of endocytoscopy for the detection of esophageal lesions: A systematic review and meta-analysis
Lu Wang, Bofu Tang, Feifei Liu, Zhenyu Jiang, Xianmei Meng
Gastroenterology & Endoscopy.2023; 1(1): 12. CrossRef
A Review of Colonoscopy in Intestinal Diseases
Seung Hong, Dong Baek
Diagnostics.2023; 13(7): 1262. CrossRef
Endoscopic Imaging for the Diagnosis of Neoplastic and Pre-Neoplastic Conditions of the Stomach
Bruno Costa Martins, Renata Nobre Moura, Angelo So Taa Kum, Carolina Ogawa Matsubayashi, Sergio Barbosa Marques, Adriana Vaz Safatle-Ribeiro
Cancers.2023; 15(9): 2445. CrossRef
A comparative study of magnifying endoscopy with narrow-band image and endocytoscopy in the diagnosis of gastric neoplasm: a pilot study
In Kyung Yoo, Jun Chul Park, Hyuk Lee, Abdullah Ozgur Yeniova, Jeong Hoon Lee, Dong Keon Yon, Joo Young Cho, Wan-Sik Lee
European Journal of Gastroenterology & Hepatology.2023; 35(5): 530. CrossRef
Advances and challenges in gastrointestinal endoscopy: a comprehensive review
Sun Gyo Lim
Journal of Innovative Medical Technology.2023; 1(1): 10. CrossRef
The development and clinical application of microscopic endoscopy for in vivo optical biopsies: Endocytoscopy and confocal laser endomicroscopy
Huahui Zhang, Zhongyu He, Ziyi Jin, Qinglai Yan, Peng Wang, Xuesong Ye
Photodiagnosis and Photodynamic Therapy.2022; 38: 102826. CrossRef
Risk factors for early gastric cancer: focus on Helicobacter pylori gastritis
Hee Seok Moon
Journal of the Korean Medical Association.2022; 65(5): 259. CrossRef

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Focused Review Series: Current Status of Endoscopy in the Management of Inflammatory Bowel Disease

Role of Advanced Endoscopic Imaging Techniques in the Management of Inflammatory Bowel Disease: Eun Soo Kim; Clin Endosc 2017;50(5):424-428. Published online September 29, 2017; DOI: https://doi.org/10.5946/ce.2017.143

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Endoscopy plays a crucial role in the management of inflammatory bowel disease (IBD) in terms of diagnosis, monitoring of mucosal status, and surveillance of colitis-associated neoplasia. Mucosal healing evaluated by endoscopy has been recognized as the target of treatment in the era of powerful biologics therapy. The optimal modality for identifying dysplasia in IBD has yet to be well defined. Increasing progress has recently been made in endoscopic technologies to more accurately assess mucosal inflammation and more effectively detect dysplasia. Here we review the data of advanced endoscopic imaging techniques such as chromoendoscopy, virtual chromoendoscopy, endocytoscopy, and confocal laser endomicroscopy in the management of IBD.

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Yingtong Chen, Xiaoyi Xu, Min Wang, Xiang Wang, Yan Wang, Yong Zhang, Jin Huang, Yuwen Tao, Wentao Fan, Lili Zhao, Li Liu, Zhining Fan
Photodiagnosis and Photodynamic Therapy.2024; 48: 104220. CrossRef
Meta-analysis of Virtual-based Chromoendoscopy Compared With Dye-spraying Chromoendoscopy Standard and High-definition White Light Endoscopy in Patients With Inflammatory Bowel Disease at Increased Risk of Colon Cancer
Mohammed El-Dallal, Ye Chen, Qianyun Lin, Shana Rakowsky, Lindsey Sattler, Joshua Foromera, Laurie Grossberg, Adam S Cheifetz, Joseph D Feuerstein
Inflammatory Bowel Diseases.2020; 26(9): 1319. CrossRef
Artificial intelligence‐assisted endoscopy changes the definition of mucosal healing in ulcerative colitis
Hiroshi Nakase, Takehiro Hirano, Kohei Wagatsuma, Tadashi Ichimiya, Tsukasa Yamakawa, Yoshihiro Yokoyama, Yuki Hayashi, Daisuke Hirayama, Tomoe Kazama, Shinji Yoshii, Hiro‐o Yamano
Digestive Endoscopy.2020;[Epub] CrossRef
Advanced neoplasia detection using chromoendoscopy and white light colonoscopy for surveillance in patients with inflammatory bowel disease
Kyeong Ok Kim, Michael V. Chiorean
Intestinal Research.2020; 18(4): 438. CrossRef
Surgical Management of Dysplasia and Cancer in Inflammatory Bowel Disease
James Ansell, Fabian Grass, Amit Merchea
Surgical Clinics of North America.2019; 99(6): 1111. CrossRef

7,170 View
181 Download
6 Web of Science
5 Crossref

Review

Application and Efficacy of Super-Magnifying Endoscopy for the Lower Intestinal Tract: Naoki Hosoe, Haruhiko Ogata; Clin Endosc 2016;49(1):37-40. Published online January 28, 2016; DOI: https://doi.org/10.5946/ce.2016.49.1.37

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Endoscopy plays a significant role in the diagnosis, management, and surveillance of colorectal cancer (CRC) and inflammatory bowel diseases (IBDs). Moreover, magnifying endoscopy and image-enhanced endoscopy has a crucial role in the clinical setting. Recently, a super-magnifying endoscope has been developed, and two devices, confocal laser endomicroscopy (CLE) and an endocytoscopy system (ECS), which allow in vivo microscopic inspection of the microstructural mucosal features of the gastrointestinal tract, are currently available. Studies on the use of ECS in CRC were reported by a Japanese group. Additionally, a few studies on the use of ECS in IBD have been reported. CLE has been shown to be reliable in assessing the activity of the disease in IBDs in both ulcerative colitis and Crohn’s disease. Various published studies evaluated the use of CLE during colonoscopy to distinguish colorectal polyp pathology and neoplasia. However, these studies are heterogeneous, and further evidence is necessary to confirm the efficacy of CLE.

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From clinical uncertainties to precision medicine: the emerging role of the gut barrier and microbiome in small bowel functional diseases
Wojciech Marlicz, Diana E Yung, Karolina Skonieczna-Żydecka, Igor Loniewski, Saskia van Hemert, Beata Loniewska, Anastasios Koulaouzidis
Expert Review of Gastroenterology & Hepatology.2017; 11(10): 961. CrossRef

7,652 View
99 Download
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