Clinical Endoscopy

Original Articles

Efficacy and safety of endoscopic submucosal dissection versus endoscopic papillectomy for managing laterally spreading duodenal papillary tumors: Yuki Kano, Ken Ohata, Toshifumi Iida, Susumu Banjoya, Tomoya Kimura, Koichi Furuta, Shinya Nagae, Yohei Ito, Hiroshi Yamazaki, Nao Takeuchi, Shunya Takayanagi, Yoshiaki Kimoto, Yuji Koyama, Seitaro Tsujino, Takashi Sakuno, Kohei Ono, Yohei Minato, Yuji Fujita, Eiji Sakai, Hideyuki Chiba; Clin Endosc 2025;58(5):712-721. Published online August 26, 2025; DOI: https://doi.org/10.5946/ce.2025.066

Graphical Abstract Abstract PDF Supplementary Material PubReader ePub

Background
/Aim: Endoscopic submucosal dissection (ESD) can be performed to treat laterally spreading duodenal papillary tumors (LSPTs). However, no studies have been conducted on the outcomes of ESDs for LSPTs.
Methods
We retrospectively compared 47 patients who underwent endoscopic papillectomies (EPs) for papillary tumors (PTs) between June 2007 and July 2023 (EP group) and eight patients who underwent ESDs for LSPTs between February 2022 and July 2023 (ESD group). In the subgroup analysis, five patients who underwent EPs for LSPTs were compared with eight patients who underwent ESDs for LSPTs.
Results
Procedure times and tumor diameters were significantly greater in the ESD group than in the EP group. The positive or unclear vertical margin (VM1/X) rate was significantly higher in the ESD group. Additional therapies were administered for patients with VM1/X in the ESD group, and no local recurrence was observed. No delayed adverse events occurred in the ESD group; however, delayed bleeding and perforation occurred in the EP group. In the subgroup analysis, the en bloc resection rate was significantly higher in the ESD group than in the EP group. The VM1/X rate did not differ significantly between groups.
Conclusions
We suggest that ESD is both feasible and safe for LSPTs.

Citations

Citations to this article as recorded by

Reducing post-endoscopic submucosal dissection pancreatitis in periampullary duodenal lesions: the role of prophylactic pancreatic duct stenting
Ari Fahrial Syam
Clinical Endoscopy.2026; 59(1): 70. CrossRef

2,220 View
98 Download
1 Web of Science
1 Crossref

Efficacy of Hypertonic Saline-Epinephrine Local Injection Around the Anal Side before Endoscopic Papillectomy for Ampullary Tumors: Naoki Okano, Yoshinori Igarashi, Ken Ito, Saori Mizutani, Hiroki Nakagawa, Kouji Watanabe, Yuuto Yamada, Kensuke Yoshimoto, Yuusuke Kimura, Susumu Iwasaki, Kensuke Takuma, Seiichi Hara, Yuui Kishimoto; Clin Endosc 2021;54(5):706-712. Published online March 10, 2021; DOI: https://doi.org/10.5946/ce.2020.208

Abstract PDF PubReader ePub

Background
/Aims: Bleeding is a complication of endoscopic snare papillectomy for ampullary tumors. This study aimed to investigate the clinical efficacy of hypertonic saline-epinephrine (HSE) local injection before endoscopic papillectomy for prevention of bleeding.
Methods
We retrospectively reviewed the data of 107 consecutive patients with ampullary tumors who underwent endoscopic papillectomy. The rates of en bloc resection, pathological resection margins, and prevention of immediate or delayed bleeding in the simple snaring resection group (Group A) and the HSE injection group (Group B) were compared.
Results
A total of 44 and 63 patients were enrolled in Groups A and B, respectively. The total complete resection rate was 89.7% (96/107); the clinical complete resection rates in Group A and Group B were 86.3% (38/44) and 92.1% (58/63), respectively (p=0.354). Post-papillectomy bleeding occurred in 22 patients. In Groups A and B, the immediate bleeding rates were 20.5% (9/44) and 4.8% (3/63), respectively (p=0.0255), while the delayed bleeding rates were 7% (3/44) and 11% (7/63), respectively (p=0.52). The rates of positive horizontal and vertical pathological margin in both groups were 27% and 16%, respectively.
Conclusions
HSE local injection was effective in preventing immediate bleeding and was useful for safely performing endoscopic papillectomy for ampullary tumors.

Citations

Citations to this article as recorded by

Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis
Marcus Hollenbach, Christian Heise, Einas Abou-Ali, Aiste Gulla, Francesco Auriemma, Kevin Soares, Galen Leung, Mark A Schattner, William R Jarnagin, Tiegong Wang, Fabrice Caillol, Marc Giovannini, Yanis Dahel, Thilo Hackert, Woo Hyun Paik, Alessandro Zer
Gut.2025; 74(3): 397. CrossRef
A Novel Clip Device for Safer and Faster Suturing in Endoscopic Papillectomy: A Retrospective Study of 241 Procedures
Kohei Takano, Kentaro Yamao, Takuya Ishikawa, Yoshihisa Takada, Yasuyuki Mizutani, Tadashi Iida, Kota Uetsuki, Takeshi Yamamura, Yoji Ishizu, Kazuhiro Furukawa, Takashi Honda, Masanao Nakamura, Hiroki Kawashima
Journal of Gastroenterology and Hepatology.2025; 40(5): 1238. CrossRef
Endoscopic papillectomy for ampullary lesions of minor papilla
Kien Vu Trung, Christian Heise, Einas Abou-Ali, Francesco Auriemma, Elias Karam, Sophia E. van der Wiel, Marco J. Bruno, Fabrice Caillol, Marc Giovannini, Viliam Masaryk, Uwe Will, Andrea Anderloni, Enrique Pérez-Cuadrado-Robles, Ana Dugic, Benjamin Meier
Gastrointestinal Endoscopy.2024; 99(4): 587. CrossRef
Endoscopic papillectomy for ampullary lesions in patients with familial adenomatous polyposis compared with sporadic lesions: a propensity score-matched cohort
Kien Vu Trung, Einas Abou-Ali, Fabrice Caillol, Woo H. Paik, Bertrand Napoleon, Viliam Masaryk, Sophia E. van der Wiel, Enrique Pérez-Cuadrado-Robles, Nicolas Musquer, Asif Halimi, Kevin Soares, Francois R. Souche, Steffen Seyfried, Maria C. Petrone, Stef
Endoscopy.2023; 55(08): 709. CrossRef
Updates in endoscopic management of ampullary and duodenal adenomas
Pravallika Chadalavada, Tilak Upendra Shah
Current Opinion in Gastroenterology.2023; 39(6): 496. CrossRef
Submucosal Epinephrine Injection Before Endoscopic Papillectomy: Less is More?
Roy L.J. van Wanrooij, Jeanin E. van Hooft
Clinical Endoscopy.2021; 54(5): 627. CrossRef

6,439 View
117 Download
6 Web of Science
6 Crossref

Focused Review Series: Cutting Edge of Advanced Therapeutic Endoscopy

Management of Remnant or Recurrent Lesions after Endoscopic Papillectomy: Ichiro Yasuda, Saito Kobayashi, Kosuke Takahashi, Sohachi Nanjo, Hiroshi Mihara, Shinya Kajiura, Takayuki Ando, Kazuto Tajiri, Haruka Fujinami; Clin Endosc 2020;53(6):659-662. Published online December 3, 2019; DOI: https://doi.org/10.5946/ce.2019.171

Abstract PDF PubReader ePub

Endoscopic papillectomy (EP) for ampullary adenomas achieves cure rates ranging from 76% to 90%, and recurrence rates are as high as 33%. If remnant or recurrent lesions after prior EP are endoscopically visible and are not suspected of intraductal extension into the biliary or pancreatic duct, repeated snaring and cutting can be performed until all visible lesions are completely resected. However, endoscopic ablative therapies, particularly argon plasma coagulation, can be attempted for tiny or uncertain remnant and recurrent lesions. In addition, intraductal radiofrequency ablation has recently been attempted for residual intraductal lesions after EP at several institutions. Although still under investigation, it has shown some promise. It might be offered as an alternative to surgery, particularly in patients who are unfit for surgery or those who refuse to undergo surgery.

Citations

Citations to this article as recorded by

Feasibility of performing cryoballoon ablation for treatment of residual ampullary neoplastic lesions using a duodenoscope
Tammy Tran, Anand Kumar
VideoGIE.2025; 10(6): 319. CrossRef
Kaizen: Perpetual improvement in biliary ablation – From technical validation to clinical translation
Eisuke Iwasaki, Fateh Bazerbachi
Digestive Endoscopy.2025; 37(9): 955. CrossRef
Follow-up and Management of Recurrent Nonmalignant Ampullary Neoplasms
Dae Jung Kim, Min Jae Yang
The Korean Journal of Gastroenterology.2025; 85(4): 431. CrossRef
Successful treatment of recurrent ampullary adenoma after endoscopic papillectomy using intraductal radiofrequency ablation
Jonghyun Lee
Journal of Innovative Medical Technology.2025; 3(2): 86. CrossRef
The timing of recurrence after endoscopic papillectomy
Samuel Han, Joshua A. Turkeltaub, Daniel Jonas, Augustin R. Attwell, Anna M. Duloy, Steven A. Edmundowicz, Hazem T. Hammad, Mihir S. Wagh, Sachin Wani, Raj J. Shah
Surgical Endoscopy.2024; 38(2): 688. CrossRef
Outcomes of rescue procedures in the management of locally recurrent ampullary tumors: A Pancreas 2000/EPC study
Elias Karam, Marcus Hollenbach, Einas Abou Ali, Francesco Auriemma, Aiste Gulla, Christian Heise, Sara Regner, Sébastien Gaujoux, Jean M. Regimbeau, Georg Kähler, Steffen Seyfried, Jean C. Vaillant, Charles De Ponthaud, Alain Sauvanet, David Birnbaum, Nic
Surgery.2023; 173(5): 1254. CrossRef
The first Russian experience of radiofrequency ablation in the treatment of adenoma of the major duodenal papilla with intraductal growth in the common bile duct
L.R. Tigiyev, Yu.S. Teterin, P.A. Yartsev, S.S. Petrikov
Pirogov Russian Journal of Surgery.2023; (8): 70. CrossRef
The Significance of Histopathological Findings on Clinical Outcomes in Endoscopic Papillectomy with Endocut
Sayaka Miyamoto, Masahiro Serikawa, Yasutaka Ishii, Yumiko Tatsukawa, Shinya Nakamura, Juri Ikemoto, Yosuke Tamura, Kazuki Nakamura, Masaru Furukawa, Yumiko Yamashita, Noriaki Iijima, Koji Arihiro, Shiro Oka
Journal of Clinical Medicine.2023; 12(21): 6853. CrossRef
Clinical outcomes of endoscopic papillectomy of ampullary adenoma: A multi-center study
Seong Ji Choi, Hong Sik Lee, Jiyeong Kim, Jung Wan Choe, Jae Min Lee, Jong Jin Hyun, Jai Hoon Yoon, Hyo Jung Kim, Jae Seon Kim, Ho Soon Choi
World Journal of Gastroenterology.2022; 28(17): 1845. CrossRef
Endoscopic papillectomy for ampullary adenoma and early adenocarcinoma: Analysis of factors related to treatment outcome and long‐term prognosis
Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Tadashi Iida, Hiroyuki Tanaka, Kazuhiro Furukawa, Masanao Nakamura, Takashi Honda, Senju Hashimoto, Akihiro Itoh, Masatoshi Ishigami, Yoshiki Hirooka, Mitsuhiro Fujishiro
Digestive Endoscopy.2021; 33(5): 858. CrossRef
Predictive factor of recurrence after endoscopic papillectomy for ampullary neoplasms
Kosuke Takahashi, Eisuke Ozawa, Ichiro Yasuda, Naohiro Komatsu, Hisamitsu Miyaaki, Ken Ohnita, Takuji Yamao, Kazuo Oba, Tatsuki Ichikawa, Kazuhiko Nakao
Journal of Hepato-Biliary-Pancreatic Sciences.2021; 28(7): 625. CrossRef
Management of obstructive jaundice in patients with neoplasms of the major duodenal papilla
Yu.S. Teterin, L.R. Tigiev, P.A. Yartsev, E.V. Stepan, M.L. Rogal, Yu.D. Kulikov
Khirurgiya. Zhurnal im. N.I. Pirogova.2021; (7): 49. CrossRef
Underwater endoscopic papillectomy for residual tumor after endoscopic papillectomy: First report
Yuki Mori, Akira Kurita, Shujiro Yazumi
Digestive Endoscopy.2020;[Epub] CrossRef
Diagnosis and treatment of benign neoplasms of the major duodenal papilla
Yu.S. Teterin, P.A. Yartsev, M.L. Rogal, L.R. Tigiev, N.V. Shavrina, K.A. Nugumanova, E.V. Stepan
Khirurgiya. Zhurnal im. N.I. Pirogova.2020; (11): 32. CrossRef

8,324 View
236 Download
9 Web of Science
14 Crossref

Case Report

Tranexamic Acid-Induced Acute Renal Cortical Necrosis in Post-Endoscopic Papillectomy Bleeding: Doo Hyun Ko, Tae Hyung Kim, Jong Wook Kim, Ja Joong Gu, Baek Hyun Yoon, Ji Hong Oh, Seung Goun Hong; Clin Endosc 2017;50(6):609-613. Published online August 9, 2017; DOI: https://doi.org/10.5946/ce.2017.021

Abstract PDF PubReader ePub

Acute renal failure can be the result of acute renal cortical necrosis (RCN), which commonly occurs from complications occurring during pregnancy. RCN is rarely caused by medications, although tranexamic acid, which is used in patients with acute bleeding for its antifibrinolytic effects, reportedly causes acute RCN in rare cases. An 82-year-old woman experienced gastrointestinal bleeding after endoscopic papillectomy of an ampullary adenoma. The bleeding was controlled with tranexamic acid administration; however, 4 days later, her urine volume decreased and she developed pulmonary edema and dyspnea. Serum creatinine levels increased from 0.8 to 3.9 mg/dL and dialysis was performed. Abdominal pelvic computed tomography with contrast enhancement revealed bilateral RCN with no renal cortex enhancement. Renal dysfunction and oliguria persisted and hemodialysis was continued. Clinicians must be aware that acute RCN can occur after tranexamic acid administration to control bleeding.

Citations

Citations to this article as recorded by

The Effects of Tranexamic Acid on Renal Outcomes in Patients Undergoing Cardiovascular Surgery: A Systematic Review and Meta-Analysis Compliant With Preferred Reporting Items for Systematic Reviews and Meta-Analyses
Bo Zhang, Li-xian He, Yun-tai Yao
Journal of Cardiothoracic and Vascular Anesthesia.2026; 40(3): 844. CrossRef
Efficacy and Safety of Tranexamic Acid in Solid Cancer Surgeries: A Systematic Review and Meta-analysis of Randomized Controlled Trials with GRADE Assessment
Asmaa Soliman, Ahmed Adel Abdel Azim, Abdullrahman Elgarawany, Ahmed S.A Osman, Ahmed Rezk, Sally Muhamed Seliem, Elsayed S. Moubarak, Suliman Hassan Abdalaziz, Israa Ahmed Qutob
Annals of Surgical Oncology.2026;[Epub] CrossRef
Tranexamic acid-induced acute bilateral renal cortical necrosis in a young trauma patient: a case report and literature review
Jérémy Berri, Moglie Le Quintrec Donnette, Ingrid Millet, Leila Chenine, Jean-Emmanuel Serre, Manal Mazloum
BMC Nephrology.2025;[Epub] CrossRef
The safety of tranexamic acid administration in total knee arthroplasty: a population‐based study from Taiwan
L.‐I. Hsu, H.‐W. Hsu, J.‐W. Chen, S.‐T. Wei, S.‐M. Hou
Anaesthesia.2023; 78(3): 303. CrossRef
Tranexamic acid in total knee arthroplasty
C. R. Bailey
Anaesthesia.2023; 78(3): 275. CrossRef
Intraoperative use of tranexamic acid to reduce blood loss during cytoreductive surgery for advanced ovarian cancer: A randomized controlled clinical trial
Xijun Yang, Mao Chai, Lingfang Xia, Zhiyong He, Xiaohua Wu, Jun Zhang
Acta Obstetricia et Gynecologica Scandinavica.2023; 102(7): 950. CrossRef
Safe and Effective Blood Preservation Through Acute Normovolemic Hemodilution and Low-Dose Tranexamic Acid in Open Partial Hepatectomy
Jian Yang, Jing Zhang, Jiayan Luo, Jie Ouyang, Qicai Qu, Qitao Wang, Yongyu Si
Journal of Pain Research.2023; Volume 16: 3905. CrossRef
Systematic review of hematuria and acute renal failure with tranexamic acid
Stephanie G. Lee, John Fralick, Christopher J. D. Wallis, Monica Boctor, Michelle Sholzberg, Michael Fralick
European Journal of Haematology.2022; 108(6): 510. CrossRef
Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients
Jashvant Poeran, Jimmy J. Chan, Nicole Zubizarreta, Madhu Mazumdar, Leesa M. Galatz, Calin S. Moucha
Anesthesiology.2021; 135(1): 57. CrossRef
N-methylamphetamine (“Crystal Meth”)−Associated Acute Renal Cortical Necrosis
Anu Gupta, Michael Kuperman, Silvi Shah
Kidney International Reports.2018; 3(6): 1473. CrossRef

9,812 View
199 Download
11 Web of Science
10 Crossref

Focused Review Series: Advanced Endoscopic Treatment for Pancreaticobiliary Diseases

Recent Advances in Endoscopic Papillectomy for Ampulla of Vater Tumors: Endoscopic Ultrasonography, Intraductal Ultrasonography, and Pancreatic Stent Placement: Jimin Han, Dong Wook Lee, Ho Gak Kim; Clin Endosc 2015;48(1):24-30. Published online January 31, 2015; DOI: https://doi.org/10.5946/ce.2015.48.1.24

Abstract PDF PubReader ePub

Since it was first described nearly three decades ago, endoscopic papillectomy (EP) has been utilized as a less invasive, alternative therapy for adenoma of the major duodenal papilla. In this article, we review the recent advances in EP, especially those pertaining to endoscopic ultrasonography (EUS), intraductal ultrasonography (IDUS), and pancreatic stent placement for the prevention of postpapillectomy pancreatitis. Because EUS and IDUS have similar diagnostic accuracies, either modality can be used for the preprocedural evaluation of ampullary tumors. Nevertheless, further technical refinements are required for a more precise evaluation. Given the paucity of data on the usefulness of EUS and/or IDUS during follow-up after EP, a well-designed study is warranted. Furthermore, pancreatic stent placement appears to have a protective effect against postpapillectomy pancreatitis; however, a prospective, randomized, controlled study with a larger number of patients is needed to assess this finding. Moreover, since pancreatic stent placement after EP is not always successful, various novel techniques have been developed to ensure reliable stent placement. Despite the recent advances in EP, further technical refinements and studies are needed to confirm their efficacy.

Citations

Citations to this article as recorded by

International Digestive Endoscopy Network consensus on the management of antithrombotic agents in patients undergoing gastrointestinal endoscopy
Seung Joo Kang, Chung Hyun Tae, Chang Seok Bang, Cheol Min Shin, Young-Hoon Jeong, Miyoung Choi, Joo Ha Hwang, Yutaka Saito, Philip Wai Yan Chiu, Rungsun Rerknimitr, Christopher Khor, Vu Van Khien, Kee Don Choi, Ki-Nam Shim, Geun Am Song, Oh Young Lee
Clinical Endoscopy.2024; 57(2): 141. CrossRef
IDEN Consensus on Management of Antithrombotic Agents in Patients Undergoing Gastrointestinal Endoscopy
Seung Joo Kang, Chung Hyun Tae, Chang Seok Bang, Cheol Min Shin, Young-Hoon Jeong, Miyoung Choi, Joo Ha Hwang, Yutaka Saito, Philip Wai Yan Chiu, Rungsun Rerknimitr, Christopher Khor, Vu Van Khien, Kee Don Choi, Ki-Nam Shim, Geun Am Song, Oh Young Lee
The Korean Journal of Gastroenterology.2024; 83(6): 217. CrossRef
International Digestive Endoscopy Network Consensus on the Management of Antithrombotic Agents in Patients Undergoing Gastrointestinal Endoscopy
Seung Joo Kang, Chung Hyun Tae, Chang Seok Bang, Cheol Min Shin, Young-Hoon Jeong, Miyoung Choi, Joo Ha Hwang, Yutaka Saito, Philip Wai Yan Chiu, Rungsun Rerknimitr, Christopher Khor, Vu Van Khien, Kee Don Choi, Ki-Nam Shim, Geun Am Song, Oh Young Lee
Gut and Liver.2024; 18(5): 764. CrossRef
Effect of prophylactic endoscopic clipping for prevention of delayed bleeding after endoscopic papillectomy for ampullary neoplasm: a multicenter randomized trial
Se Woo Park, Tae Jun Song, Jin Seok Park, Jae Hyuk Jun, Tae Young Park, Dong Wook Oh, Sang Soo Lee, Myung-Hwan Kim
Endoscopy.2022; 54(08): 787. CrossRef
Efficacy analysis of hemostatic spray following endoscopic papillectomy: A multicenter comparative study
Kyong Joo Lee, Tae Hoon Lee, Jae Hee Cho, Jong Jin Hyun, Sung Ill Jang, Seok Jeong, Jin‐Seok Park, Jae Kook Yang, Don Haeng Lee, Dong Ki Lee, Sang Heum Park
Journal of Gastroenterology and Hepatology.2022; 37(11): 2138. CrossRef

13,035 View
172 Download
5 Web of Science
5 Crossref

Original Article

Endosonographic Preoperative Evaluation for Tumors of the Ampulla of Vater Using Endoscopic Ultrasonography and Intraductal Ultrasonography: Naoki Okano, Yoshinori Igarashi, Seiichi Hara, Kensuke Takuma, Itaru Kamata, Yui Kishimoto, Takahiko Mimura, Ken Ito, Yasukiyo Sumino; Clin Endosc 2014;47(2):174-177. Published online March 31, 2014; DOI: https://doi.org/10.5946/ce.2014.47.2.174

Abstract PDF PubReader ePub

Background/Aims

In recent years, endoscopic snare papillectomy has been performed to treat tumors of the ampulla of Vater. This procedure requires accurate preoperative evaluation. In this study, we diagnosed the focal extension of such tumors by using endoscopic ultrasonography (EUS) and intraductal ultrasonography (IDUS), and examined the indications for endoscopic snare papillectomy.

Methods

The subjects were 48 patients with a papillary tumor (13 patients, surgical resection; 35 patients, endoscopic snare papillectomy) who were evaluated preoperatively with EUS and IDUS. The tumor-node-metastasis classification was used for the endosonographic evaluation and pathological diagnosis of these tumors.

Results

The diagnostic accuracy of EUS was 97% for diagnosing adenomas and pTis tumors, 73% for pT1 tumors, 50% for pT2 tumors, and 50% for pT3-4 tumors, for an overall accuracy of 85% for T-staging. The diagnostic accuracy of IDUS was 94% for adenomas and pTis tumors, 73% for pT1 tumors, 50% for pT2 tumors, and 100% for pT3-4 tumors, for an overall accuracy of 80% for T-staging.

Conclusions

EUS and IDUS are highly capable of evaluating tumors of the ampulla of Vater preoperatively. However, these techniques are not sufficient for evaluating the focal extension of carcinomas preoperatively. Currently, endoscopic snare papillectomy is adequate for treating adenomas and pTis tumors.

Citations

Citations to this article as recorded by

Diagnostic Work-up and Evaluation of Nonmalignant Ampullary Neoplasms
Il Sang Shin, Yun Nah Lee, Jong Ho Moon
The Korean Journal of Gastroenterology.2025; 85(3): 253. CrossRef
The Role of Endoscopic Ultrasound in Ampullary Lesion Management
Caterina Stornello, Chiara Cristofori, Davide Checchin, Maria Grazia de Palo, Sabina Grillo, Giulia Peserico, Dario Quintini, Mario Gruppo, Ottavia De Simoni, Alberto Fantin
Diagnostics.2024; 14(17): 1855. CrossRef
Clinical practice guidelines for endoscopic papillectomy
Takao Itoi, Shomei Ryozawa, Akio Katanuma, Hiroki Kawashima, Eisuke Iwasaki, Shinichi Hashimoto, Kenjiro Yamamoto, Toshiharu Ueki, Yoshinori Igarashi, Kazuo Inui, Naotaka Fujita, Kazuma Fujimoto
Digestive Endoscopy.2022; 34(3): 394. CrossRef
Diagnostic accuracy of endoscopic ultrasound and intraductal ultrasonography for assessment of ampullary tumors: a meta-analysis
Xiaohua Ye, Lei Wang, Zhendong Jin
Scandinavian Journal of Gastroenterology.2022; 57(10): 1158. CrossRef
The Long-Term Outcomes of Endoscopic Papillectomy and Management of Cases of Incomplete Resection: A Single-Center Study
Shinichiro Muro, Hironari Kato, Akihiro Matsumi, Yuki Ishihara, Yosuke Saragai, Shuntaro Yabe, Saimon Takata, Daisuke Uchida, Takeshi Tomoda, Kazuyuki Matsumoto, Shigeru Horiguchi, Hiroyuki Okada
Journal of Gastrointestinal Surgery.2021; 25(5): 1247. CrossRef
Endoscopic papillectomy for ampullary adenoma and early adenocarcinoma: Analysis of factors related to treatment outcome and long‐term prognosis
Hiroki Kawashima, Eizaburo Ohno, Takuya Ishikawa, Tadashi Iida, Hiroyuki Tanaka, Kazuhiro Furukawa, Masanao Nakamura, Takashi Honda, Senju Hashimoto, Akihiro Itoh, Masatoshi Ishigami, Yoshiki Hirooka, Mitsuhiro Fujishiro
Digestive Endoscopy.2021; 33(5): 858. CrossRef
Endoscopic management of ampullary tumors: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Geoffroy Vanbiervliet, Marin Strijker, Marianna Arvanitakis, Arthur Aelvoet, Urban Arnelo, Torsten Beyna, Olivier Busch, Pierre H. Deprez, Lumir Kunovsky, Alberto Larghi, Gianpiero Manes, Alan Moss, Bertrand Napoleon, Manu Nayar, Enrique Pérez-Cuadrado-Ro
Endoscopy.2021; 53(04): 429. CrossRef
Endoscopic Mucosal Resection of Adenocarcinoma at the Minor Duodenal Papilla: A Case Report and Suggestions for the Optimal Treatment Strategy
Takao Sato, Ryota Sagami, Hidefumi Nishikiori, Hiroaki Tsuji, Keiji Sato, Tsutomu Daa, Kazunari Murakami
Internal Medicine.2021; 60(16): 2593. CrossRef
Management of obstructive jaundice in patients with neoplasms of the major duodenal papilla
Yu.S. Teterin, L.R. Tigiev, P.A. Yartsev, E.V. Stepan, M.L. Rogal, Yu.D. Kulikov
Khirurgiya. Zhurnal im. N.I. Pirogova.2021; (7): 49. CrossRef
A duodenal ampullary tumor with malignant transformation of papillary polyps: a case report and literature review
Wenhui Mo, Jingjing Li, Ying Dai, Jianqing Chen, Xuanfu Xu
Journal of International Medical Research.2021;[Epub] CrossRef
Methods and outcome of the endoscopic treatment of ampullary tumors
Jan-Werner Poley, Sara Campos
Therapeutic Advances in Gastrointestinal Endoscopy.2020; 13: 263177451989978. CrossRef
Insights and updates on endoscopic papillectomy
Kenjiro Yamamoto, Eisuke Iwasaki, Takao Itoi
Expert Review of Gastroenterology & Hepatology.2020; 14(6): 435. CrossRef
A Comprehensive Approach to the Management of Benign and Malignant Ampullary Lesions: Management in Hereditary and Sporadic Settings
Donald R. Campbell, Jeffrey H. Lee
Current Gastroenterology Reports.2020;[Epub] CrossRef
Preliminary experience of hybrid endoscopic submucosal dissection by duodenoscope for recurrent laterally spreading papillary lesions
Zi-Kai Wang, Fang Liu, Yun Wang, Xiang-Dong Wang, Ping Tang, Wen Li
World Journal of Gastroenterology.2020; 26(37): 5673. CrossRef
Clinical outcomes of ampullary neoplasms in resected margin positive or uncertain cases after endoscopic papillectomy
Arata Sakai, Masahiro Tsujimae, Atsuhiro Masuda, Takao Iemoto, Shigeto Ashina, Kohei Yamakawa, Takeshi Tanaka, Shunta Tanaka, Yasutaka Yamada, Ryota Nakano, Yu Sato, Manabu Kurosawa, Takuya Ikegawa, Seiji Fujigaki, Takashi Kobayashi, Hideyuki Shiomi, Yosh
World Journal of Gastroenterology.2019; 25(11): 1387. CrossRef
Surgical method choice and coincidence rate of pathological diagnoses in transduodenal ampullectomy: A retrospective case series study and review of the literature
Feng Liu, Jia-Lin Cheng, Jing Cui, Zong-Zhen Xu, Zhen Fu, Ju Liu, Hu Tian
World Journal of Clinical Cases.2019; 7(6): 717. CrossRef
Endoscopic management of ampullary neoplasm
Sunguk Jang
International Journal of Gastrointestinal Intervention.2019; 8(3): 110. CrossRef
Comparison of postoperative early and late complications between pancreas-sparing duodenectomy and pancreatoduodenectomy
Yusuke Nakayama, Masaru Konishi, Naoto Gotohda, Yuichiro Kato, Hidetoshi Aizawa, Masashi Kudo, Satoshi Okubo, Daigoro Takahashi, Yasunori Nishida, Kazuhiko Kitaguchi, Shinichiro Takahashi
Surgery Today.2017; 47(6): 705. CrossRef
Traitement endoscopique du cancer superficiel de l’ampoule de Vater
P. Ah-Soune, J. -M. Gonzalez, A. Benezech, M. Barthet
Acta Endoscopica.2017; 47(1): 11. CrossRef
Endoscopic versus surgical treatment of ampullary adenomas: a systematic review and meta-analysis
Ernesto Quaresma Mendonça, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura, Dalton Marques Chaves, André Kondo, Leonardo Zorrón Cheng Tao Pu, Felipe Iankelevich Baracat
Clinics.2016; 71(1): 28. CrossRef
Recent Advances in Endoscopic Papillectomy for Ampulla of Vater Tumors: Endoscopic Ultrasonography, Intraductal Ultrasonography, and Pancreatic Stent Placement
Jimin Han, Dong Wook Lee, Ho Gak Kim
Clinical Endoscopy.2015; 48(1): 24. CrossRef
The role of endoscopy in ampullary and duodenal adenomas
Krishnavel V. Chathadi, Mouen A. Khashab, Ruben D. Acosta, Vinay Chandrasekhara, Mohamad A. Eloubeidi, Ashley L. Faulx, Lisa Fonkalsrud, Jenifer R. Lightdale, John R. Saltzman, Aasma Shaukat, Amy Wang, Brooks D. Cash, John M. DeWitt
Gastrointestinal Endoscopy.2015; 82(5): 773. CrossRef
Endoscopic Diagnosis of Ampullary Tumors Using Conventional Endoscopic Ultrasonography and Intraductal Ultrasonography in the Era of Endoscopic Papillectomy: Advantages and Limitations
Jong Ho Moon
Clinical Endoscopy.2014; 47(2): 127. CrossRef

8,143 View
97 Download
25 Web of Science
23 Crossref

A Case of Ampullary Adenomyoma Associated with Dilatations of Pancreatic and Biliary Ducts: Byung Uk Lee, M.D., Jei So Bang, M.D., Soo Hyun Yang, M.D., Ji Ho Kim, M.D., Jong Hoon Byun, M.D., Won Keun Si, M.D., Moon Hyung Lee, M.D. and Bo Kyoung Choi, M.D.; Korean J Gastrointest Endosc 2010;40(6):391-395. Published online June 30, 2010

Abstract PDF: Adenomyoma is a nonneoplastic lesion that can be found anywhere in the gastrointestinal tract, but it's rarely found in the ampulla of Vater. To the best of our knowledge, it is a benign lesion, but most cases are misdiagnosed as carcinoma or adenoma by a preoperative endoscopic or radiologic procedure, and this leads to unnecessarily extensive surgical resection. We report here on a case of ampulla of Vater adenomyoma that resulted in biliary and pancreatic duct dilatation. The tumor was diagnosed by endoscopic papillectomy. (Korean J Gastrointest Endosc 2010;40:391-395)

2,906 View
19 Download

Pancreatic and Biliary Strictures Associated with Cholangitis and Bile Reflux Following Endoscopic Papillectomy of Ampullary Adenoma: Dae-Geun Song, M.D., Jei So Bang, M.D., Won Hyeong Park, M.D., Tae Gyoon Kim, M.D., Hyun Gyung Park, M.D., Bo Young Min, M.D., Su Hyun Yang, M.D. and Jong Hoon Byun, M.D.; Korean J Gastrointest Endosc 2009;39(1):50-54. Published online July 30, 2009

Abstract PDF: Ampullary adenoma is rare but clinically important because it is a premalignant lesion. Use of endoscopic gastroduodenoscopy has increased detection of adenoma of the major duodenal papilla. Endoscopic papillectomy is a promising technique to supplant surgical ampullectomy, because it is less aggressive and more stable. However, various complications include bleeding, perforation, pancreatitis and cholangitis. We describe pancreatic and biliary strictures associated with cholangitis, and bile reflux through the pancreatic duct to the minor duodenal papilla after endoscopic papillectomy. Pancreatic and biliary strictures have not been hitherto reported complications. We performed endoscopic papillary balloon dilatation, minor papilla papillotomy and inserted a drain tube through the accessory pancreatic duct. (Korean J Gastrointest Endosc 2009;39: 50-54)

2,491 View
14 Download

Endoscopic Papillectomy for Tumors of the Duodenal Major Papilla: Myoung Hwan Kim, M.D., Chang Mo Moon, M.D., Seungmin Bang, M.D., Byung Kyu Park, M.D., Seung Woo Park, M.D., Si Young Song, M.D. and Jae Bock Chung, M.D.; Korean J Gastrointest Endosc 2006;32(2):87-93. Published online February 27, 2006

Abstract PDF: Background
/Aims: A surgical resection has traditionally been used to treat tumors of the duodenal major papilla. However, radical surgery may cause significant morbidity and mortality. Endoscopic papillectomy has been reported in patients with benign papillary tumors. We evaluated the safety and outcomes of endoscopic papillectomy in patients with a papillary tumor. Methods: Between January 1994 and December 2003, fifteen patients with ampullary tumors underwent an endoscopic papillectomy using a snare resection. Endoscopic papillectomy was performed in 13 patients diagnosed with an adenoma and in 2 patients diagnosed with an adenocarcinoma, who were contraindicated for surgery. Results: Endoscopic papillectomy was performed in fifteen patients (11 men, 4 women: median age 61.7 years). All the tumors were removed either "en bloc" (14 tumors) or in a "piecemeal" fashion (one tumor). Ten patients were available for follow-up (median, 20.9 months: range, 1∼62 months). The procedure-related complications were bleeding (n=1), pancreatitis (n=3), and a duodenal perforation (n=1). The follow-up endoscopy revealed a recurrent adenocarcinoma in 2 patients after 13 months (20%). Conclusions: Endoscopic papillectomy is a useful alternative for treating a papillary adenoma. The relatively high incidence of pancreatitis this study suggests that stenting into the pancreatic duct will be needed to prevent postprocedure pancreatitis. (Korean J Gastrointest Endosc 2006;32:87⁣93)

2,324 View
9 Download

First
Prev
Page of 1
Next
Last

Search