Clinical Endoscopy

Review

Endoscopic activity in inflammatory bowel disease: clinical significance and application in practice: Kyeong Ok Kim; Clin Endosc 2022;55(4):480-488. Published online July 28, 2022; DOI: https://doi.org/10.5946/ce.2022.108

Endoscopy is vital for diagnosing, assessing treatment response, and monitoring surveillance in patients with inflammatory bowel disease (IBD). With the growing importance of mucosal healing as a treatment target, the assessment of disease activity by endoscopy has been accepted as the standard of care for IBD. There are many endoscopic activity indices for facilitating standardized reporting of the gastrointestinal mucosal appearance in IBD, and each index has its strengths and weaknesses. Although most endoscopic indices do not have a clear-cut validated definition, endoscopic remission or mucosal healing is associated with favorable outcomes, such as a decreased risk of relapse. Therefore, experts suggest utilizing endoscopic indices for monitoring disease activity and optimizing treatment to achieve remission. However, the regular monitoring of endoscopic activity is limited in practice owing to several factors, such as the complexity of the procedure, time consumption, inter-observer variability, and lack of a clear-cut, validated definition of endoscopic response or remission. Although experts have recently suggested consensus-based definitions, further studies are needed to define the values that can predict long-term outcomes.

Citations

Citations to this article as recorded by

Treatment targets in IBD: is it time for new strategies?
Fabrizio Fanizzi, Ferdinando D'Amico, Laurent Peyrin-Biroulet, Silvio Danese, Axel Dignass
Best Practice & Research Clinical Gastroenterology.2025; : 101990. CrossRef
Laboratory Tests in Inflammatory Bowel Disease: An Evidence-Based Approach to Daily Practice
Katelin Durham, Tyler Atagozli, David E. Elliott, M. Nedim Ince
Biomedicines.2025; 13(2): 491. CrossRef
Combining mechanistic modeling with machine learning as a strategy to predict inflammatory bowel disease clinical scores
Jaehee V. Shim, Markus Rehberg, Britta Wagenhuber, Piet H. van der Graaf, Douglas W. Chung
Frontiers in Pharmacology.2025;[Epub] CrossRef
Endoscopic healing in IBD: Still the target to achieve?
Andrea Buda, Tommaso Pessarelli, Giovanni Aldinio, Manuela De Bona, Marietta Iacucci, Gian Eugenio Tontini
Digestive and Liver Disease.2025; 57(5): 519. CrossRef
Plasminogen Activator Inhibitor 1 Is a Novel Faecal Biomarker for Monitoring Disease Activity and Therapeutic Response in Inflammatory Bowel Diseases
Boldizsár Jójárt, Tamás Resál, Diána Kata, Tünde Molnár, Péter Bacsur, Viktória Szabó, Árpád Varga, Kata Judit Szántó, Petra Pallagi, Imre Földesi, Tamás Molnár, József Maléth, Klaudia Farkas
Journal of Crohn's and Colitis.2024; 18(3): 392. CrossRef
Ocular endothelial dysfunction in pediatric inflammatory bowel disease
Giovanni Di Nardo, Mariachiara Di Pippo, Letizia Zenzeri, Maurizio Mennini, Marisa Piccirillo, Silvia Furio, Giovanna Quatrale, Melania Evangelisti, Pasquale Parisi, Livia Lucchini, Alessandro Ferretti, Maria Pia Villa, Gianluca Scuderi, David Sarzi Amadè
Journal of Pediatric Gastroenterology and Nutrition.2024; 78(6): 1297. CrossRef
Consenso de endoscopia en enfermedad inflamatoria intestinal de la Organización Panamericana de Crohn y Colitis (PANCCO) y la Sociedad Interamericana de endoscopia (SIED)
Viviana Parra-Izquierdo, Fabio Leonel Gil-Parada, Fabian Juliao-Baños, Carolina Pavez-Ovalle, William Otero-Regino, Juan Sebastian Frías-Ordoñez, Asadur Tchekmedyian, Juan Eloy Paredes Mendez, Rodrigo Dorelo, Kenneth Ernest-Suarez, Marcos Leites Madera, M
Revista de Gastroenterología del Perú.2024;[Epub] CrossRef
Crohn’s disease management: translating STRIDE-II for UK clinical practice
Karen Kemp, Mark A. Samaan, Ajay M. Verma, Alan J. Lobo
Therapeutic Advances in Gastroenterology.2024;[Epub] CrossRef
Different levels of healing in inflammatory bowel diseases: mucosal, histological, transmural, barrier and complete healing
Markus F Neurath, Michael Vieth
Gut.2023; 72(11): 2164. CrossRef
Use of Standardized Inflammatory Bowel Disease Endoscopy Scores in Clinical Practice
Jill K J Gaidos, Badr Al Bawardy, Francis A Farraye, Miguel Regueiro
Crohn's & Colitis 360.2023;[Epub] CrossRef
Evaluation of Disease Activity in Inflammatory Bowel Disease: Diagnostic Tools in the Assessment of Histological Healing
Alina Ecaterina Jucan, Otilia Gavrilescu, Mihaela Dranga, Iolanda Valentina Popa, Ioana-Ruxandra Mihai, Vasile-Claudiu Mihai, Gabriela Stefanescu, Vasile Liviu Drug, Cristina Cijevschi Prelipcean, Radu-Alexandru Vulpoi, Oana-Bogdana Barboi, Irina Ciortesc
Biomedicines.2023; 11(11): 3090. CrossRef
Active Assessment of Inflammatory Bowel Disease
金良肖
Advances in Clinical Medicine.2022; 12(12): 11023. CrossRef

11,060 View
524 Download
10 Web of Science
12 Crossref

First
Prev
Page of 1
Next
Last

Search