Korean J Gastrointest Endosc > Volume 13(2); 1993 > Article
Korean Journal of Gastrointestinal Endoscopy 1993;13(2): 335-339.
자연소실된 원발성 식도 악성 림프종 1예 ( Spontaneous Regression of Primary Malignant Lymphoma of the Esophagus )
함기백, 신용준, 임대순, 김원호, 문영명, 강진경, 박인서, 조장환, 임현이, 박찬일 (Ki Baik Hahm, Yong Joon Shim, Dae Soon Yim, Won Ho Kim, Young Myung Moon, Jin Kyung Kang, In Suh Park, Jang Whan Cho, Hyun Yi Yim and Chan Il Park)
Gastrointestinal involvement has been reported to occur in about 5 to l0% of patients with lymphoma. The most common gastrointestinal site for a lymphoma is the stomach, followed by the small intestine and ileocecal region. When lymphoma is found in the esap us, generally it is with contiguous involvement of the gastric fundus, the cervical node, secondary to mediastinal lymph node compression, or a late manifestation of advanced desease. Such cases cannot be labeled as primary esophageal lymphoma. A search of the literature reveals that there have been about 20 or more published cases classified as esophageal lymphoma. However, more than ten cases are indistingishable from the case of distal esophageal involvement by gastric lymphoma. In 1935, Chiolero described a case of midesophageal stricture, which at autopsy was consistent with Hodgkin's disease for the first time. Berman reported an authentic case of primary histiocytic lymphoma confined to the lower esophagus. Only six or more cases were reported in literature until the present time. Here, a 30-year-old man with substernal discomfort was shown to have a mass lesion on the esophagus. The mass was proved to be malignant lymphoma on the histologic examination. This may be the first report dealing with spontaneous regression of maligant lymphoma of the esophagus possibly associated with the use of cimetidine.
Key Words: Primary esophageal lymphoma , Regression
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