Korean Journal of Gastrointestinal Endoscopy 1995;15(3): 495-500.
증례 : 식도 소세포암과 위선암이 병발한 원발성 중복암 1예 ( Case Reports : Synchronous Double Primary Cancer of Esophageal Small Cell Carcinoma and Gastric Adenocarcinoma )
정준모, 최용환, 권영오, 윤영미, 안병철, 김성국 (Joon Mo Chung, Yong Hwan Choi, Young Oh Kweon, Young Mee Yun, Byeong Cheal Ahn and Sung Kook Kim)
Abstract
Double primary cancer means that more than two cancers with different origin exist independently in an individual. The diagnosis of double primary cancer was determined by following criteria. Each of the tumors must present a definite picture of malignancy, and each must be distinct, and the probability of one being a metastasis of the other must be excluded. Small cell carcinoma has a distinct biological behavior such as, early invasion and metastasis, a rapid clinical course, and significant sensitivity to chemotherapy. Small cell carcinoma in the esophagus is relatively rare, and rarer when it is combined with other malignant disease. We have experienced a case of double primary cancer, a 70-year-old man with esophageal small cell carcinoma and gastric adenocarcinoma, which were diagnosed by gastrointestinal endoscopic biopsy. A review of the Korean medical literature failed to reveal any previously described case of esophageal small cell carcinoma with gastric adenocareinoma. We report this case with review of literatures.
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