Korean J Gastrointest Endosc > Volume 15(1); 1995 > Article
Korean Journal of Gastrointestinal Endoscopy 1995;15(1): 12-25.
원저 : 소화성궤양에 의한 출혈에서 내시경적 Fibrin Glue 및 Hypertonic Saline Epinephrine ( Original Articles : Comparison of Hemostatic Effect of Endoscopic Injection with Fibrin Glue ( FG ) and Hypertonic Saline - epinephrine ( HSE ) for Peptic Ulcer Bleeding - A prospective randomized trial - )
문영명, 강진경, 박인서, 전재윤, 정재복, 한광협, 김원호, 송시영, 원욱희 (Young Myung Moon, Jin Kyung Kang, In Suh Park, Chae Yoon Chon, Jae Bock Chung, Kwang Hyub Han, Won Ho Kim, Si Young Song and Wook Hee Won)
Endoscopic injection therapy using various different agents(ethanol, polidocanol, epinephrine with and without hypertonic saline, etc.) is considered as the least expensive and effective technique to obtain hemostasis in peptic ulcer bleeding, however most of these agents induce tissue necrosis or degeneration. Theoretically the injection of fibrin glue in peptic ulcer bleeding may be safer than that of other agents, however, to date, there have been no data from randomized clinical trials on the comparison of the efficacies between these agents. To compare the hemostatic efficacy between FG[Beriplast P, Behring, Germany] and HSE[3% saline and epinephrine(1: 10,000)], we conducted a prospective, randomized, clinical trial among one hundred twenty-seven patients with peptic ulcer bleeding from March, 1992 to December, 1993 and in whom a visible vessel or active bleeding was identified.
Key Words: Fibrin glue , Hypertonic saline - epinephrine , Endoscopic injection therapy , Peptic ulcer bleeding
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