Korean Journal of Gastrointestinal Endoscopy 1996;16(5): 793-799.
증례 : 식도 위장관 ; Formalin 도포요법으로 치료한 출혈성 방사선 직장염 1예 - 증례 보고 - ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Formalin Therapy for Hemorrhagic Radiation Proctitis )
이상인, 박인서, 박효진, 손승국, 송종원, 정준근, 안태완 (Sang In Lee, In Suh Park, Hyo Jin Park, Seung Kook Sohn, Jong Won Song, Jun Keun Jung and Tae Wan Ahn)
Abstract
Hemorrhagic radiation proctitis is infrequently seen in patients receiving pelvic irradiation. The treatment of hemorrhagic ralation proctitis is often difficult. Many patients need reyeated hospitalizations and blood transfusions. Occasionally patiets will develop severe or recurrent rectal bleeding. In case of massive bleeding requiring excessive transfusion, colonic diversion by construction of a colostomy or excision of the diseased segment may be inevitable. However, surgical procedures in these patients are associated with a high mortality and morbidity. Moreover, medical therapy is usually ineffective. Recently formalin therapy has been introduced as a simple and effective treatment for hemorrhagic radiation proctitis. We experienced a 69 year-old woman patient who developed severe homorrhagic proctitis 1 year after radiotherapy for carcinoma of the cervix. She had not improved by conservative management and required blood tranafusions and repetitive hospitalizations. After local application of a 4% formalin solution in the diseased rectum under caudal anesthesia, the bleeding immediately stopped and the patient was discharged from the hospital, and no recurrence has been observed until now. (Korean J Gastrointest Endosc 16: 793~ 798, 1996)
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