Korean Journal of Gastrointestinal Endoscopy 1996;16(4): 608-613.
증례 : 식도 위장관 ; 위장관 출혈을 보였던 독성표피융해 1예 ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Toxic Epidermal Necrolysis Concomittantly Presented with GI Bleeding and Its Gastrofiberscopic Findings )
김나영, 이계희, 임선희, 이규현, 박용주, 안경주, 임병철, 신준우 (Na Young Kim, Kye Heui Lee, Seon Hee Lim, Gyu Hyun Lee, Yong Ju Park, Kyung Ju Ahn, Byung Chul Lim and Joon Woo Shin)
Abstract
Toxic epidermal necrolysis (T~EN) is a severe mucocutaneous disease characterized by epidermal necrosis possibly extended to the entire body surface and involving multiple internal organs. Digestive tract may be involved too, but there is few report about gastrointestinal lesion in patient with TEN. Recently we experienced a case of TEN with gastrointestinal bleeding in previously healthy 32-year-old woman. The condition developed three days after the initiation of treatment with NSAID and progressed caudally, involving 60 percent of the skin surfaces. During a period of admission gastrointestinal bleeding was noticed. The gastrofiberscopy showed diffuse superficial mucosal lesion with oozing from swollen friable and erythematous mucosa. The skin lesion was progressed inspite of withdrawal of causative agents. The patient was expired due to combined septic shock 10 days later. We report this case with gastrofiberscopic findings and a brief review of literature. (Korean J Gastrointest Endosc 16: 608~ 612, 1996)
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