Korean J Gastrointest Endosc > Volume 42(6); 2011 > Article
Korean Journal of Gastrointestinal Endoscopy 2011;42(6): 341-348.
Endoscopic Treatment of Primary Esophageal Motility Disorders
Joon Seong Lee, M.D., Ph.D.
Department of Internal Medicine, Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea
Abstract
Treatment of primary esophageal motility disorders, particularly achalasia, has developed enormously. The proven treatments for these patients include mostly endoscopic methods. Currently, pneumatic dilatation and laparoscopic myotomy with partial fundoplication are both useful for treating achalasia. A young man with high lower esophageal sphincter pressure might be best indicated for a laparoscopic myotomy with fundoplication, whereas an older patient with a high risk for surgery or vigorous achalasia may for a candidate for an endoscopic botulinum toxin injection. Pneumatic balloon dilatation is the choice of treatment for other cases of achalasia. The best treatment option for a nonachalasia spastic motor disorder of the esophagus may be endoscopic injection of botulinum toxin. In the future, endoscopic injection of neuronal stem cells could be the best treatment option for achalasia.
Key Words: Esophageal motility disorder, Esophageal achalasia, Balloon dilatation
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