Korean J Gastrointest Endosc > Volume 17(1); 1997 > Article
Korean Journal of Gastrointestinal Endoscopy 1997;17(1): 79-84.
증례 : 식도 위장관 ; 교원성 대장염 1예 ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Collagenous Colitis )
최재홍, 나병규, 오상우, 이지현, 정상무, 박선미, 윤세진, 이복희, 정화숙, 성노현 (Jae Hong Choi, Byoung Ku Na, Sang Woo Oh, Jee Hyun Lee, Moo Sang Jung, Seun Mee Park, Sae Jin Youn, Bok Hee Lee, Hwa Sook Jung and No Hyun Sung)
The term "collagenous colitis" was coined by Lindstrom in 1976 to describe the patient with chronic watery diarrhea who had normal rectal mucosa by proctoscopy but who had a thick subepithelial collagenous deposit on biopsy, and now collagenous colitis is recognized as one of the more common causes of chronic diarrhea of obscure origin. But in this country only a few case has been reported. We have seen a 68-year-old man with chronic watery diarrhea with abdominal pain. Physical examination, laboratory and radiologic studies were no abnormal finding. Colonoscopy disclosed grossly normal mucosa through the entire colon but by histologic examination there are chronic inflammation in the lamina propria and thickened subepithelial collagen layer. Symptoms and pathologic findings of patient improved after treatment with sulfasalazine and prednisolone. (Korean J Castraintest Endosc 17: 79-84, 1997)
Key Words: Collagenous colitis , Sulfasalazine
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