Korean Journal of Gastrointestinal Endoscopy 1999;19(4): 574-580.
대장암 주변에서 관찰되는 백색반점의 병리조직학적 특성과 임상적 의의 ( Histopathological Features and the Clinical Significance of White Spots around Colon Cancer )
조진만(Jin Man Cho),김효종(Hyo Jong Kim),장영운(Yeong-Woon Chang),박일랑(Il-Lang Park),동석호(Seok Ho Dong),김윤화(Yoon Hwa Kim),김병호(Byong-Ho Kim),이정일(Jeong-Il Lee),장린(Rin Chang)
Abstract
Background/Aims: To investigate the difference between colorectal adenocarcinomas with white spots (foamy cells) and those without white spots, clinically and histopathologically, were examined 37 cases of colorectal adenocarcinomas were classified in this study. Methods: Two groups: those with white spots and those without. In each case, evidence of lymph node and liver metastasis was sought. Immunoreactive staining for macrophage was performed. Results: Increased incidence of exophytic tumors was found (73%, p=0.028) in the group with white spots. The incidences of lymph node metastasis were 33% vs. 45% between the group with white spots and the group of without, but the difference was not statistically significant. Conclusions: These results suggested that foamy cells might have a beneficial role in colorectal cancer, although they were not statistically significant. Therefore, further prospective study be warranted. (Korean J Gastrointest Endosc 19: 574∼577, 1999)
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