Korean Journal of Gastrointestinal Endoscopy 2000;21(6): 909-916.
메네트리어병 국내 보고 16예의 임상적 고찰 ( Clinical Features of Menetrier's Disease in Korea - A report of sixteen cases - )
임윤정(Yoon Jung Lim),이풍렬(Poong Ryul Lee),김영호(Young Ho Kim),이순진(Soon Jin Lee),이미숙(Mi Sook Lee),강태욱(Tae Wook Kang),박동일(Dong Il Park),이준행(Joon Haeng Lee),장재권(Jae Gwon Jang),손희정(Hee Jung Son),김재준(Jae Joon Kim),백승운(Seung Woon Baek),이종철(Jong Chul Lee),최규완(Gyu Wan Choi)
Abstract
Background/Aims: Menetrier's disease is a poorly defined condition that is f unknown origin, characterized by giant folds in the stomach. The histoiogic fentures are foveolar hyperplasia and cystic dilatation of the gland. We presented the characteristic findings of Menetirer's disease in Korea with a review of literatures to understand the Menetirer's disease more precisely, Methods: The sixteen cases of Menetrier's disease was reported in Korea. We analyzed their age, sex, symptoms, signs, laboratory findings and treatments, retrospectively, Results: The average age was 46 years. There were 11 men and 4 women. The most common symptom was epigastric pain (94%). The most common sign were epigastric tenderness (69%) and pretibial pitting edema (63%). Patients were often associated with the hypoalbuminemia (73%). All patients showed hypertrophic folds on either gastrofiberscopy or upper gastrointestinal series, All patients showed foveolar hyperplasia histologically. Three patients were operated to control a massive upper gastrointesinal bleeding. Two patients were operated to control the intractable edema. Two patients were operated to exclude gastrie malignancy, Conclusions: Menetrier's disease showed broad clinical features such as epigastric pain, hypoalbuminemia, massive hematemesis and mimicking gastric malignancy. The giant gastric folds and foveolar hyperplasia were the most commom and important findings in the Menetrier's disease.
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