김명임(Myung Im Kim),장영운(Young Woon Chang),동석호(Seok Ho Dong),박경분(Kyoung Bun Park),이동근(Dong Kuen Lee),김경진(Kyeong Jin Kim),김효종(Hyo Jong Kim),김병호(Byung Ho Kim),이정일(Joung Il Lee),장린(Rin Chang)
Abstract
The terms "gastrointestinal stromal tumor" (GIST) have been applied to mesenchymal tumos that represent neither typical leiomyoma nor schwannoma. The majority of GISTs are Located in the stomach and small intestine, and only 4% of GISTs are found in duodenum. The most important characteristic is their indolent, slow-growing nature, rendering the most common definitions of malignancy invalid and inapplicable. Clinical and pathological criteria to differentiate benign from malignant GISTs are not well established. Tumor size and mitoic activity are commonly considered as important features, allowing for the prediction of biological behaviour and outcome. The case of a 87-year-old male patient who was presented with melena and acute anemia is herein reported. Esophagogastroduodenoscopy and computed tomography of the abdomen revealed two submucosal tumors in the stomach and duodenum. Histological and immunohistochemical studies on the surgical resection specimen revealed a gastrointestinal stromal tumor of an uncommiteed type, with no evidence of increased mitotic activity. The patient was treated with local excision of the tumors and is now in a favorable state. (Korean J Gastrointest Endosc 2000;21:554-558)
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