Korean Journal of Gastrointestinal Endoscopy 2000;20(3): 213-217.
궤양성 대장염에 병발한 비전형적 유암종 1예 ( A Case of an Atypical Carcinoid Tumor Arising in Ulcerative Colitis )
정용희(Yong Hee Joung),김효종(Hyo Jong Kim),김경진(Kyeong Jin Kim),동석호(Seok Ho Dong),김윤화(Yun Hwa Kim),김병호(Byung Ho Kim),장영운(Young Woon Chang),이정일(Jung Il Lee),이주희(Ju Hue Lee),장린(Ring Chang)
Abstract
Ulcerative colitis is a chronic inflammatory bowel disease manifested by diffuse continuous mucosal and submucosal inflammation. Adenocarcinoma of the colon may be complicated in the long-standing, extensive ulcerative colitis. But the case of an atypical carcinoid tumor arising in the chronic ulcerative colitis has been very rarely reported. A case was experienced involving a 54-year-old woman with chronic ulcerative pancolitis that was complicated by an atypical carcinoid tumor of the sigmoid colon. A small, flat, elevated lesion was found at the sigmoid colon, 8 years after the initial diagnosis of ulcerative colitis had been made. The microscopic finding of the lesion showed the nest of moderately differentiated, medium sized cells with large nuclei. The immunohistochemical stains for cytokeratin, NSE, chromogranin A, and synaptophysin were positive.The patient was treated with a total colectomy accompanied with an ileostomy, and is now in a very favor able state of recovery.
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