Korean Journal of Gastrointestinal Endoscopy 2000;20(1): 68-72.
위 전정부 및 십이지장에 비용종성 선종을 동반한 가족성 선종성 용종증 1예 ( A Case of Antral and Duodenal Nonpolypoid Adenomas in a Patient with Familial Adenomatous Polyposis )
이영석(Young Suk Lee),최소진(So Jean Choi),이창렬(Chang Ryoul Lee),이준호(Jun Ho Lee),이동석(Dong Suk Lee),김우성(Woo Seung Kim),박희승(Hee Seung Park),최성호(Seong Ho Choi)
Abstract
Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited colon cancer-predisposing disorder, characterized by the development of innumerable adenomas in the large intestine. Polyps are present in the upper gastrointestinal tract in almost all FAP patients and there is a peculiar predilection for adenomatous change in the duodenum. Colonic adenomas in FAP are commonly observed as polyps but nonpolypoid adenomas can also be seen in the upper gastrointestinal tract. Careful endoscopic examination is needed for detecting such nonpolypoid lesions. At present, the adenoma-carcinoma sequence is thought to exist also in the duodenum, and malignancy of the duodenum represents one of the most common causes of mortality among patients with FAP. Therefore, careful periodic follow-up of upper intestinal endoscopies are recommended in patients with this disease, in consideration to the possible development of duodenal nonpolypoid adenomatous lesions. A case involving an experience of antral and duodenal nonpolypoid adenomas in a patient with FAP is herein reported. (Korean J Gastrointest Endosc 2000;20:68 72)
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