Korean J Gastrointest Endosc > Volume 23(2); 2001 > Article
Korean Journal of Gastrointestinal Endoscopy 2001;23(2): 93-99.
악성 담관협착에서 Niti - S 스텐트 및 Wallstent 의 비교 ( A New Covered Biliary Metal Stent versus Uncovered Wallstent for Malignant Biliary Obstruction )
서정훈(Jeong Hun Suh),송시영(Si Young Song),박승우(Seung Woo Park),이세준(Se Joon Lee),정준표(Jun Pyo Chung),정재복(Jae Bock Chung),강진경(Jin Kyung Kang)

In order to provide a complete ob- stacle to tumoral growth, we designed a new self- expandible metal stent fully covered with polyurethane membrane. The purpose cf the study was to compare the safety and effectiveness of a new membrane-covered Niti-S stent versus conventional uncovered Wallstent.
In a prospective trial, 59 patients with malignant extrahepatic biliary obstruction received either a newly developed covered metal stent (Niti-S stent, 30 cases) or an uncovered metal stent (Wallstent, 29 cases) by the endoscopic trans-papillary route.
Effective biliary decompression was achieved in all patients initially, and short-term results were similar in both groups. Stent failure was observed in 4 of the 30 patients (13%) after a median period of 165 days in the Niti-S group and in 8 of the 29 patients (28%) after a median period of 152 days in the Wallstent group. The reasons of stent failure were occlusion (n=3) and migration (n=l) in the covered Niti-S stent group and occlusion (n=8) in uncovered Wallstent group. According to the Kaplan-Meier life table analysis, the patency rates after 90, 180, and 360 days were 100%, 90%, and 74% in covered Niti-S stent group and 100%, 73%, and 61% in uncovered Wallstent group respectively. The occluded membrane-covered Niti-S stent was easily removed endoscopically and a new Niti-S stent was reinserted in one patient.
The new, membrane-covered Niti-S stent has a lower stent failure rate and a tendency toward long-term patency rate compared to uncovered Wallstent. The covering may effectively prevent tumor ingrowth and it is sometimes possible to remove an occluded Niti-S stent. (Korean J Gastrointest Endosc 2001;23:93-99)
Key Words: 악성 담관협착 , 막을 부착한 Niti - S 스텐트 , 막을 부착하지 않은 Wallstent , Malignant biliary obstruction , Membrane - covered Niti - S stent , Uncovered Wallstent
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