Korean Journal of Gastrointestinal Endoscopy 2001;22(1): 21-26.
궤양성 대장염에서 확대색소내시경술 (Magnifying Chromoscopy)의 유용성 ( Usefulness of Magnifying Chromoscopy in Ulcerative Colitis )
신정우(Jung Woo Shin),임창영(Chang Young Lim),최유식(You Sik Choi)
Abstract
Background/Aims: Ulcerative colitis is an inflammatory bowel disease with unknown etiology, which has waxed and waned course. It is diagnosed by colon study, pathology, and especially colonoscopy. It is difficult to differentiate between ulcerative colitis and other infectious colitis, especially amebic colitis, and to confirm of remnant lesion by endoscopic findings. Methods: Magnifying colonoscopy has 100 time magnifying power compared to 30 time of conventional colonoscopy, By spraying 0,2% indigo carmine dye, we evaluated the magnifying and microscopic findings of 31 colonic mucosa of 23 patients with ulcerative colitis. Results: Initial and magnifying chromoscopic findings in ulcerative colitis were loss of cryptal opening 72% (13/18), loss of submucosal vessel 89% (16/18), mucosal denudation (or microscopic erosion) 83% (15/1S), and mucosal unevenness 94% (17/18). Recovery rate of magnifying chromoscopic findings after treatment in ulcerative colitis were in crytal opening S0% (+8/10), submucosal vascularity 60% (6/10), mucosal denudation (microscopic erosion) 30% (3/10), and in mucosal unevenness 40% (4/10). Conclusions: It is suggested that magnifying chromoscopic findings in ulcerative colitis may be useful in initial diagnosis and confirmation of remnant lesion, but, not in prediction of clinical severity. (Korean J Gastrointest Endosc 2001;22:21 - 26)