Korean J Gastrointest Endosc > Volume 26(6); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;26(6): 405-409.
심한 임상경과를 보이는 Mallory-Weiss 증후군의 임상적 특징
한양대학교 의과대학 내과학교실
A Study on Clinical Characteristics of Mallory-Weiss Syndrome with Complicated Course
Hang Lak Lee, M.D., Dong Soo Han, M.D., Jong Pyo Kim, M.D., Jin Bae Kim, M.D., Joon Yong Park, M.D., Joo Hyun Sohn, M.D. and Joon Soo Hahm, M.D.
Department of Internal Medicine, Hanyang University Kuri Hospital, Gyeonggi-do, Korea

Mallory-Weiss syndrome is a benign and self-limiting disease, but occasionally cases with complications are encountered. The aim of this study was to identify the risk factors for complicated course and predisposing factors of Mallory-Weiss syndrome, and its associated conditions.
Fifty-nine patients diagnosed as having Mallory-Weiss syndrome were subjects of this study. Patients' medical records were reviewed retrospectively. A complicated course was defined if there was a need for transfusion of >6 pints, evidence of shock, rebleeding or angiographic or surgical interventions.
Risk factors for a complicated Mallory-Weiss syndrome in univariate analysis were the followings; low hemoglobin, melena, presence of visible vessel or active bleeding on initial endoscopy. In multivariate analysis, the presence of visible vessel and active bleeding on initial endoscopy were the only significant risk factors. Predisposing factors of Mallory-Weiss syndrome were as follows: vomiting after alcohol intake (62.7%), vomiting without alcohol (18.6%), nausea (1%), cough (1%), seizure (1%) and unknown etiology (13.6%). Associated medical conditions were as follows: alcoholic liver disease (45.8%), hiatal hernia (27.1%) and liver cirrhosis (18.6%).
We suggest that the presence of visible vessel and active bleeding on initial endoscopy are a independent risk factors of Mallory-Weiss syndrome with a complicated course. In such patients, aggressive treatment and careful observations are essential. (Korean J Gastrointest Endosc 2003;26:405⁣409)
Key Words: Mallory-Weiss syndrome, Complication, Risk factors
주요어: Mallory-Weiss 증후군, 합병증, 위험 인자
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