Korean J Gastrointest Endosc > Volume 27(2); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;27(2): 70-75.
만성 위축성 위염과 고가스트린혈증에 동반된 다발성 위유암종 1예
울산대학교 의과대학 서울아산병원 소화기내과학교실, *병리학교실
A Case of Multiple Gastric Carcinoids Associated with Chronic Atrophic Gastritis and Hypergastrinemia
Myoung Kuk Jang, M.D., Gin Hyug Lee, M.D., Sung Sook Lee, M.D., Chan Sun Park, M.D., Jeong Sik Byeon, M.D., Yun Jung Lee, M.D., Seung Jae Myung, M.D., Hwoon Yong Jung, M.D., Suk Kyun Yang, M.D., Weon Seon Hong, M.D., Jin Ho Kim, M.D., Young Il Min, M.D. a
Division of Gastroenterology, Departments of Internal Medicine and *Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Gastric carcinoid tumors are so rare that they constitute less than 1% of total primary gastric tumors. They are classified into 3 types: (1) gastric carcionoid associated with chronic atrophic gastritis (type I), (2) gastric carcinoids associated with Zollinger-Ellison syndrome (ZES) or multiple endocrine neoplasm (MEN) type 1 (type II), and (3) sporadic gastric carcinoid (type III). A 55-year-old man underwent a medical check-up. Five polypoid masses were incidentally detected in the cardia, fundus and midbody whose size ranged from 0.5 cm to 1.6 cm in diameter. Tumor cells were strongly positive for cytokeratin, synaptophysin and chromogranin staining. Biopsies from the body and fundus showed severe atrophy. Fasting serum gastrin level was highly increased, 1,098 pg/mL. There was, however, no evidence of the presence of ZES or MEN type 1. The patient underwent total gastrectomy for complete resection and has remained free of any complications with normal serum gastrin level. (Korean J Gastrointest Endosc 2003;27:70⁣75)
Key Words: Carcinoid tumor, Chronic atrophic gastritis, Gastrin
주요어: 위유암종, 만성 위축성 위염, 가스트린
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