Korean J Gastrointest Endosc > Volume 27(4); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;27(4): 244-248.
장결핵과 연관된 속발성 유전분증 1예
울산대학교 의과대학 서울아산병원 소화기내과, *진단병리과
A Case of Secondary Amyloidosis Associated with Intestinal Tuberculosis
Jungkwon Kim, M.D., Seung-Jae Myung, M.D., Jungjoon Choi, M.D., Gideog Kim, M.D., Dongryoul Oh, M.D., Sujin Koh, M.D., Won-Jang Kim, M.D., Jintae Park, M.D., Ginhyuk Lee, M.D., Suk-Kyun Yang, M.D., Weon-Seon Hong, M.D., Jin-Ho Kim, M.D., Young-Il Min, M.D
Departments of Internal Medicine and *Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
The secondary amyloidosis (AA type), a complication of inflammation or infection, is caused by the deposition of serum amyloid protein A in various organs. The clinical manifestations of amyloidosis are various according to involved organs. The gastrointestinal tract is one of the commonly affected organs. However, the endoscopic findings of gastrointestinal amyloidosis are nonspecific, and symptoms are diverse. Hepatic involvement of amyloidosis rarely leads to hepatic dysfunction, threfore is not a clinical concern. We report a 54-year-old women with intestinal tuberculosis whose major symptom was watery diarrhea lasting several months. The amyloid deposits were histologically proven in the rectum of which mucosa showed redness and swelling endoscopically and hepatic involvement of amyloidosis was suspected on abdominopelvic CT scan. After anti-tuberculosis medication for 6 months, abdominopelvic CT scan showed resolution of hepatic involvement and colonoscopy revealed improvement of redness and loss of vascularity of the rectum.
Key Words: Amyloidosis, Intestinal tuberculosis
주요어: 유전분증, 장결핵
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