Korean J Gastrointest Endosc > Volume 27(4); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;27(4): 239-243.
직장에 발생한 원발성 신경내분비 소세포암 1예
김정환·김영호·정재홍·송봉근·최성철·이풍렬·김재준·이종철
성균관대학교 의과대학 삼성서울병원 내과학교실
A Case of Primary Small Cell Neuroendocrine Carcinoma of the Rectum
Jeong Hwan Kim, M.D., Young-Ho Kim, M.D., Jae Hong Jung, M.D., Bong Geun Song, M.D., Sung Chul Choi, M.D., Poong-Lyul Rhee, M.D., Jae J. Kim, M.D. and Jong Chul Rhee, M.D.
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Abstract
Neuroendocrine carcinoma of the colon is a very rare entity. However, this type of tumor is known to have aggressive progression and poor prognosis. A case of a 72-year-old male is presented in this report. A 3 cm sized tumor was found on the rectum with multiple liver metastases. The pathological findings including a positive immunohistochemical staining for synaptophysin and cytokeratin done with colonoscopic biopsy and liver biopsy confirmed the tumor as a neuroendocrine carcinoma. The nomenclature and definition of this disease still remains somewhat unclear, and not a small population of this disease may thus have been misdiagnosed and treated as other less aggressive entities, such as carcinoid tumor. The necessity to make an accurate differential diagnosis in such cases is thus emphasized because of different treatments and clinical courses. For its rarity and clinical significance, we report this case with a review of the literatures. (Korean J Gastrointest Endosc 2003;27:239-243)
Key Words: Neuroendocrine carcinoma, Rectum
주요어: 신경내분비 소세포암, 직장
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