Korean J Gastrointest Endosc > Volume 27(4); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;27(4): 234-238.
Amoxicillin에 의해 유발된 국소 출혈성 대장염 1예
을지의과대학 노원을지병원 내과학교실, *해부병리학교실
A Case of Amoxicillin-induced Segmental Hemorrhagic Colitis
Chung Hyeon Kim, M.D., Yun Ju Jo, M.D., Jeong Soo Cho, M.D., Eun Gyu Lee, M.D., Won Wook Choi, M.D., Tae Hun Kim, M.D., Yeon Ho Joo, M.D., Young Sook Park, M.D. and Wan Seop Kim, M.D.*
Departments of Internal Medicine and *Pathology, Eulji Hospital, Eulji College of Medicine, Seoul, Korea
Clinically, we often encounter patients who have symptoms of loose stool or diarrhea due to the use of antibiotics. Psuedomembranous colitis is the most frequent, but hemorrhagic colitis is rare. Penicillin-like-antibiotics-induced hemorrhagic colitis was infrequently reported in abroad, but in Korea, quinolone-induced colitis was reported. We found a case that the patient had the hematochezia after use of amoxicillin for eradication of H. pylori. Colonoscopic abnormalities showed superficial ulceration and mucosal edematous change without pseudomembrane on the ascending and transverse colon. We diagnosed the amoxicillin- induced hemorrhagic colitis by clinical course, colonoscopic findings, histologic findings and other laboratory results for differential diagnosis. This disease is rare but rapidly recovered after the withdrawal of the antibiotics and has a good prognosis. Therefore, we should differentiate this disease from hemorrhagic colitis of other causes by history taking.
Key Words: Hemorrhagic colitis, Antibiotic-associated colitis, Amoxicillin
주요어: 출혈성 대장염, 항생제 기인성 대장염, Amoxicillin
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