Korean Journal of Gastrointestinal Endoscopy 2003;27(4): 211-215.
Candida glabrata에 의한 식도염 1예
이정훈ㆍ이옥재ㆍ민현주ㆍ강도연ㆍ문인규ㆍ이기동ㆍ김현진ㆍ김태효ㆍ정운태
경상대학교 의과대학 내과학교실
A Case of Candida glabrata Esophagitis
Jung Hoon Lee, M.D., Ok Jae Lee, M.D., Hyun Joo Min, M.D., Do Yeon Kang, M.D., In Gyu Moon, M.D., Kee Dong Lee, M.D., Hyun Jeen Kim, M.D., Tae Hyo Kim, M.D. and Woon Tae Jung, M.D.
Departments of Internal Medicine, Gyeongsang National University College of Medicine, Jinju, Korea
Abstract
Candida species are the most common cause of all cases of infectiousesophagitis, and Candida albicans is the main causative organism of these infections. Candida glabrata has been considered a relatively nonpathogenic saprophyte of the normal flora of healthy individuals, rarely causing serious infection in human. However, following the widespread and increased use of broad-spectrum antibiotics and immunosuppressive therapy, the frequency of infections caused by C. glabrata has increased significantly. C. glabrata is of special importance because C. glabrata infections are associated with a highest mortality rate and resistant to azole antifungal agents, especially fluconazole. We report a case of C. glabrata esophagitis resistant to fluconazole but treated effectively with amphotericin B.
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