Abstract

Candida species are the most common cause of all cases of infectious esophagitis, and Candida albicans is the main causative organism of these infections. Candida glabrata has been considered a relatively nonpathogenic saprophyte of the normal flora of healthy individuals, rarely causing serious infection in human. However, following the widespread and increased use of broad-spectrum antibiotics and immunosuppressive therapy, the frequency of infections caused by C. glabrata has increased significantly. C. glabrata is of special importance because C. glabrata infections are associated with a highest mortality rate and resistant to azole antifungal agents, especially fluconazole. We report a case of C. glabrata esophagitis resistant to fluconazole but treated effectively with amphotericin B.

• Keywords: Candidial esophagitis, Candida glabrata