Korean J Gastrointest Endosc > Volume 27(6); 2003 > Article
Korean Journal of Gastrointestinal Endoscopy 2003;27(6): 515-520.
경구용 Sodium Phosphate 일 회 복용 시 대장내시경 전처치 효과
곽병원 내과
Effectiveness of Single-dose Sodium Phosphate on Bowel Preparation
Kang-Wook Chung, M.D., Jin-Il Park, M.D., Jong-Hyuk Park, M.D., Do-Yeon Hwang, M.D., Hyung-Hwa Lee, M.D., Dong-Soo Lee, M.D., Dong-Hoon Kwack, M.D., Ji-Young Seo, M.D., Jae-Jin Jung, M.D., Young-Hak Lee, M.D., Young-Sung Kim, M.D. and Dong-Hyup Kwak, M.D
Department of Internal Medicine, Kwak's Hospital, Daegu, Korea

Oral sodium phosphate has been shown to be effective and safe but causes intravascular volume contraction, changes in serum calcium and phopshate level, and sleep disturbance when given two doses every 12 hours. Because the evening dose is inconvenient for many patients, we gave single morning dose, and compared it with conventional 12-hour-split dose.
Sixty one patients drank 90 mL of sodium phosphate at 7:00 AM and 58 patients drank 45 mL of sodium phosphate at 7:00 PM and 7:00 AM respectively.
There was no statistical difference in bowel cleansing between two groups (p=0.871). There was no significant difference in patient's tolerance and symptoms between two groups except sleep deprivation which was more frequent in the split dose group. None of the patients complained of postural dizziness or presyncope in both groups. Serum phosphate levels were increased and serum calcium levels were decreased after preparation in both groups, but patients showed no significant clinical symptoms such as tetany.
This study suggests that giving a single morning dose of sodium phosphate is effective, well tolerated and safe in most patients for precolonoscopic cleansing, compared to conventional split dose of 12-hour interval. (Korean J Gastrointest Endosc 2003;27:515⁣520)
Key Words: Colonoscopy, Bowel preparation, Sodium phophsphate, Single dose
주요어: 대장내시경, 전처치, 인산나트륨, 일 회 복용
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