Korean J Gastrointest Endosc > Volume 28(1); 2004 > Article
Korean Journal of Gastrointestinal Endoscopy 2004;28(1): 18-24.
단분절 바렛식도에서 발생한 식도선암 2예
정영걸·박종재·김정한·유상균·이지연·윤 익·박기호 김진용·김재선·박영태·정운용*·김철환*·이창홍
고려대학교 의과대학 구로병원 내과학교실, *해부병리학교실
Two Cases of Adenocarcinoma Arising from Short Segment Barrett's Esophagus
Young Kul Jung, M.D., Jong-Jae Park, M.D., Jeong Han Kim, M.D., Sang Kyun Yu, M.D., Ji Yeon Lee, M.D., Ik Yoon, M.D., Ki Ho Park, M.D., Jin Yong Kim, M.D., Jae Seon Kim, M.D., Young-Tae Bak, M.D., Woon Yong Jeong, M.D.*, Chul Hwan Kim, M.D.* and Chang Hon
Departments of Internal Medicine and *Pathology, Korea University College of Medicine, Seoul, Korea
Barrett's esophagus is considered as a premalignant condition in which columnar epithelium replaces the normal esophageal squamous epithelium. The diagnosis of Barrett's esophagus is based on the endoscopic finding of columnar epithelium lining the distal esophagus and histologic confirmation of the presence of specialized intestinal metaplasia. According to the extent of the metaplastic lining from the esophagogastric junction, Barrett's esophagus has been divided into long-segment (≥3 cm in length) and short-segment (<3 cm in length). Long- segment Barrett's esophagus can be easily identified at endoscopy, but it is difficult to separate short-segment Barrett's esophagus from intestinal metaplasia of cardia. It has been reported that Barrett's CK 7/20 pattern is an objective marker of Barrett's mucosa, and can differentiate Barrett's mucosa from gastric intestinal metaplasia. We report here two cases of adenocarcinoma of esophagus arising from short-segment Barrett's esophagus, diagnosed by endoscopic and histologic findngs, and treated by endoscopic mucosal resection. (Korean J Gastrointest Endosc 2004;28:18⁣24)
Key Words: Esophagus, Adenocarcinoma, Short segment Barrett's esophagus, Cytokeratin 7/20
주요어: 식도선암, 단분절 바렛식도, CK 7/20
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