Korean J Gastrointest Endosc > Volume 28(5); 2004 > Article
Korean Journal of Gastrointestinal Endoscopy 2004;28(5): 242-246.
위와 십이지장에 발생한 원발성 말초성 T-세포성 림프종
김원석·이기명·고보람·송영준·최준혁·김재근*·한재호·함기백·김진홍·조성원
아주대학교 의과대학 소화기내과학교실, *진단방사선학교실, 병리학교실
Primary Peripheral T-Cell Lymphoma of the Stomach and Duodenum
Won Seok Kim, M.D., Kee Myung Lee, M.D., Bo Ram Koh, M.D., Young Jun Song, M.D.,Joon Hyuck Choi, M.D., Jai Keun Kim, M.D.*, Jae Ho Hahn, M.D., Ki Baik Hahm, M.D.,Jin Hong Kim, M.D. and Sung Won Cho, M.D.
Departments of Gastroenterology, *Diagnostic Radiology and Pathology, Ajou University College of Medicine, Suwon, Korea
Abstract
About 90% of primary gastrointestinal lymphomas originate from the B-cell and less than 10% from the T-cell. In respect of anatomical location, the stomach is the most common site of gastrointestinal lymphomas followed by the ileum, colon, and rectum. However, esophagus and duodenal lymphomas are infrequently involved. Primary T-cell lymphoma of the duodenum is not common and peripheral T-cell lymphoma of the duodenum is very rare. In Korea, there has been no case report of peripheral T-cell lymphoma which simultaneously involved the stomach and duodenum. In this report, we present a case of primary peripheral T-cell lymphoma of the duodenum and stomach. A 63-year-old man was hospitalized complaining of weight loss of 15 kg and dyspepsia for 2 months. Esophagogastroduodenoscopy showed a large annular infiltrative lesion in the descending portion of the duodenum. At the posterior side of the upper body of the stomach, an ill-defined, broad, flat, and infiltrative lesion was also noted. Microscopic examination of the biopsy specimen showed that atypical bizzare lymphocytes infiltrated the mucosa of the duodenum and stomach. The lymphocyte was positive for CD3, CD5 and negative for CD20, CD23, and CD56 by immunohistochemistry. We made a diagnosis of primary peripheral T-cell lymphoma of the stomach and duodenum. We report a case of peripheral T-cell lymphoma of the stomach and duodenum with a review of the literature. (Korean J Gastrointest Endosc 2004;28:242⁣246)
Key Words: Peripheral T-cell lymphoma, Stomach, Duodenum
주요어: 말초성 T-세포성 림프종, 위장, 십이지장
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