Korean J Gastrointest Endosc > Volume 28(6); 2004 > Article
Korean Journal of Gastrointestinal Endoscopy 2004;28(6): 307-311.
원발성 위 소세포암 1예
배상석·최재홍·채희복·박선미·윤세진·이기형·김석형*·성노현*
충북대학교 의과대학 내과, *해부병리과
A Case of Small Cell Carcinoma in the Stomach
Sang Seok Bae, M.D., Jae Hong Choi, M.D., Hee Bock Chae, M.D., Seon Mee Park, M.D.,
Departments of Internal Medicine and *Pathology, Chungbuk National University College of Medicine, Chungbuk, Korea
Abstract
Small cell carcinoma (SmCC) of stomach is a very rare and aggressive malignancy with extremely poor prognosis. Most patients with gastric SmCC die within 1 year of diagnosis. A standard treatment for gastric SmCC has not been established, but surgical excision and/or combination chemotherapy should be considered to promote long term survival. We report a case of small cell carcinoma of stomach in a 66-year-old woman with dysphagia. A gastroscopic examination revealed a polypoid mass with ulceration on the lesser curvature of the gastric body extending to the gastro-esophageal junction. An endoscopic biopsy showed a solid proliferation of small, monotonous tumor cells with hyperchromatic nuclei and scanty cytoplasm. Immunohistochemically, the neoplastic cells were positive for chromogranin, synaptophysin and NSE, and negative for CD45. No tumor was detected on examination of the chest. Therefore, primary SmCC was diagnosed preoperatively. (Korean J Gastrointest Endosc 2004;28:307⁣311)
Key Words: Dysphagia, Gastric small cell carcinoma
주요어: 연하곤란, 위 소세포암
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